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Protein
Submitted name:

STEAP2 metalloreductase

Gene

Steap2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-917977 Transferrin endocytosis and recycling

Names & Taxonomyi

Protein namesi
Submitted name:
STEAP2 metalloreductaseImported
Submitted name:
Six transmembrane epithelial antigen of prostate 2 (Predicted), isoform CRA_bImported
Gene namesi
Name:Steap2Imported
Synonyms:Steap2_predictedImported
ORF Names:rCG_41006Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1307050 Steap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei210 – 231HelicalSequence analysisAdd BLAST22
Transmembranei260 – 283HelicalSequence analysisAdd BLAST24
Transmembranei304 – 325HelicalSequence analysisAdd BLAST22
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei390 – 411HelicalSequence analysisAdd BLAST22
Transmembranei431 – 453HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000006076

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007977

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 117F420_oxidoredInterPro annotationAdd BLAST87
Domaini259 – 404Ferric oxidoreductaseInterPro annotationAdd BLAST146

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IF4F Eukaryota
COG2085 LUCA
GeneTreeiENSGT00390000008042
KOiK14738
OMAiTHHEDAV
OrthoDBiEOG091G0F9X
TreeFamiTF332031

Family and domain databases

InterProiView protein in InterPro
IPR013130 Fe3_Rdtase_TM_dom
IPR036291 NAD(P)-bd_dom_sf
IPR028939 P5C_Rdtase_cat_N
PfamiView protein in Pfam
PF03807 F420_oxidored, 1 hit
PF01794 Ferric_reduct, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

D4A6H3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESISMMGSP KTLETFLPNG INGIKDARKV TVGVIGSGDF AKSLTIRLIR
60 70 80 90 100
CGYHVVIGSR NPKFASEFFP HVVDVTHHED ALTKTNIIFV AIHREHYTSL
110 120 130 140 150
WDLRHLLVGK VLIDVSNNMR VNQYPESNAE YLASLFPDSL IVKGFNVISA
160 170 180 190 200
WALQLGPKDA SRQVYICSNN IQARQQVIEL ARQLNFIPVD LGSLSSAKEI
210 220 230 240 250
ENLPLRLFTL WRGPVVVAIS LATFFFIYSF VRDVIHPYAR NQQSDFYKIP
260 270 280 290 300
IEIVNKTLPI VAITLLSLVY LAGLLAAAYQ LYYGTKYRRF PPWLDTWLQC
310 320 330 340 350
RKQLGLLSFF FAVVHVAYSL CLPMRRSERY LFLNMAYQQV HANIENAWNE
360 370 380 390 400
EEVWRIEMYI SFGIMSLGLL SLLAVTSIPS VSNALNWREF SFIQSTLGYV
410 420 430 440 450
ALLITTFHVL IYGWKRAFAE EYYRFYTPPN FVLALVLPSI VLLGKMMLLL
460 470 480
PCIGRKLKRI KKGWEKSQFL EEGMGGTVPH LSPERVTVM
Length:489
Mass (Da):55,792
Last modified:April 20, 2010 - v1
Checksum:i604FC17BCD76BBD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108334 Genomic DNA No translation available.
CH474013 Genomic DNA Translation: EDL84336.1
RefSeqiNP_001101316.1, NM_001107846.1
XP_006236094.1, XM_006236032.3
XP_006236096.1, XM_006236034.3
XP_006236097.1, XM_006236035.2
XP_006236098.1, XM_006236036.3
XP_008760925.1, XM_008762703.2
UniGeneiRn.203614

Genome annotation databases

EnsembliENSRNOT00000007977; ENSRNOP00000007977; ENSRNOG00000006076
GeneIDi312052
KEGGirno:312052
UCSCiRGD:1307050 rat

Similar proteinsi

Entry informationi

Entry nameiD4A6H3_RAT
AccessioniPrimary (citable) accession number: D4A6H3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health