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D4A6H3

- D4A6H3_RAT

UniProt

D4A6H3 - D4A6H3_RAT

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Protein
Submitted name:

Protein Steap2

Gene

Steap2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. cupric reductase activity Source: Ensembl
  2. ferric-chelate reductase (NADPH) activity Source: Ensembl
  3. transporter activity Source: Ensembl

GO - Biological processi

  1. copper ion import Source: Ensembl
  2. endocytosis Source: Ensembl
  3. ferric iron import into cell Source: Ensembl
  4. Golgi to plasma membrane transport Source: Ensembl
  5. regulated secretory pathway Source: Ensembl
  6. response to hormone Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Steap2Imported
Submitted name:
Six transmembrane epithelial antigen of prostate 2 (Predicted), isoform CRA_bImported
Gene namesi
Name:Steap2Imported
Synonyms:Steap2_predictedImported
ORF Names:rCG_41006Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 4

Organism-specific databases

RGDi1307050. Steap2.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. early endosome Source: Ensembl
  3. integral component of Golgi membrane Source: Ensembl
  4. plasma membrane Source: Ensembl
  5. trans-Golgi network transport vesicle Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

TransmembraneImported

Phylogenomic databases

GeneTreeiENSGT00390000008042.
KOiK14738.
OMAiFFFASVH.
OrthoDBiEOG7Z0JWH.
TreeFamiTF332031.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR013130. Fe3_Rdtase_TM_dom.
IPR016040. NAD(P)-bd_dom.
IPR028939. ProC_N.
[Graphical view]
PfamiPF03807. F420_oxidored. 1 hit.
PF01794. Ferric_reduct. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4A6H3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESISMMGSP KTLETFLPNG INGIKDARKV TVGVIGSGDF AKSLTIRLIR
60 70 80 90 100
CGYHVVIGSR NPKFASEFFP HVVDVTHHED ALTKTNIIFV AIHREHYTSL
110 120 130 140 150
WDLRHLLVGK VLIDVSNNMR VNQYPESNAE YLASLFPDSL IVKGFNVISA
160 170 180 190 200
WALQLGPKDA SRQVYICSNN IQARQQVIEL ARQLNFIPVD LGSLSSAKEI
210 220 230 240 250
ENLPLRLFTL WRGPVVVAIS LATFFFIYSF VRDVIHPYAR NQQSDFYKIP
260 270 280 290 300
IEIVNKTLPI VAITLLSLVY LAGLLAAAYQ LYYGTKYRRF PPWLDTWLQC
310 320 330 340 350
RKQLGLLSFF FAVVHVAYSL CLPMRRSERY LFLNMAYQQV HANIENAWNE
360 370 380 390 400
EEVWRIEMYI SFGIMSLGLL SLLAVTSIPS VSNALNWREF SFIQSTLGYV
410 420 430 440 450
ALLITTFHVL IYGWKRAFAE EYYRFYTPPN FVLALVLPSI VLLGKMMLLL
460 470 480
PCIGRKLKRI KKGWEKSQFL EEGMGGTVPH LSPERVTVM
Length:489
Mass (Da):55,792
Last modified:April 20, 2010 - v1
Checksum:i604FC17BCD76BBD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06029373 Genomic DNA. No translation available.
CH474013 Genomic DNA. Translation: EDL84336.1.
RefSeqiNP_001101316.1. NM_001107846.1.
XP_006236094.1. XM_006236032.2.
XP_006236095.1. XM_006236033.2.
XP_006236096.1. XM_006236034.2.
XP_006236097.1. XM_006236035.1.
XP_006236098.1. XM_006236036.2.
UniGeneiRn.203614.

Genome annotation databases

EnsembliENSRNOT00000007977; ENSRNOP00000007977; ENSRNOG00000006076.
GeneIDi312052.
KEGGirno:312052.
UCSCiRGD:1307050. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06029373 Genomic DNA. No translation available.
CH474013 Genomic DNA. Translation: EDL84336.1 .
RefSeqi NP_001101316.1. NM_001107846.1.
XP_006236094.1. XM_006236032.2.
XP_006236095.1. XM_006236033.2.
XP_006236096.1. XM_006236034.2.
XP_006236097.1. XM_006236035.1.
XP_006236098.1. XM_006236036.2.
UniGenei Rn.203614.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000007977 ; ENSRNOP00000007977 ; ENSRNOG00000006076 .
GeneIDi 312052.
KEGGi rno:312052.
UCSCi RGD:1307050. rat.

Organism-specific databases

CTDi 261729.
RGDi 1307050. Steap2.

Phylogenomic databases

GeneTreei ENSGT00390000008042.
KOi K14738.
OMAi FFFASVH.
OrthoDBi EOG7Z0JWH.
TreeFami TF332031.

Miscellaneous databases

NextBioi 664552.
PROi D4A6H3.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR013130. Fe3_Rdtase_TM_dom.
IPR016040. NAD(P)-bd_dom.
IPR028939. ProC_N.
[Graphical view ]
Pfami PF03807. F420_oxidored. 1 hit.
PF01794. Ferric_reduct. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A6H3_RAT
AccessioniPrimary (citable) accession number: D4A6H3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3