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D4A5S1 (D4A5S1_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length827 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). RuleBase RU004435

Sequence similarities

Belongs to the peptidase C19 family.

Contains USP domain. SAAS SAAS001394

Sequences

Sequence LengthMass (Da)Tools
D4A5S1 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 0CDDBE1042A3022C

FASTA82794,128
        10         20         30         40         50         60 
MDPVLIHAQV QLWSAKAGMS KSRNAFIETF IGKREVKLIL YFSTGKIKAL QLYNNIKSVV 

        70         80         90        100        110        120 
LRTYGEDQNY LHLTFKNNDF LFVEKLTTMD ARRLKRFLDK IYQSNLRAAR RSGERPGDPS 

       130        140        150        160        170        180 
TSAQELSSSP PEGHLKASSA CFESAKESEM CLFRQLPLLP PSSASLNAVG LLESQFMKRK 

       190        200        210        220        230        240 
RFFLGAEKEK QNLKGSTREF ETNLVVSISN EKGKERGVRA VEISKAGFGF PFETNYPEEG 

       250        260        270        280        290        300 
SVNVRDLNDL ITKLFSPLLF ETHYIENGLD WHEYMETFLL DPEKSWQGLP NVGNTCYINV 

       310        320        330        340        350        360 
VLQSLCSIPL FVNDLFNQGF PWIKPPKDDF NMRLMQLLVL KDIYNARTRQ KLLIGITKAL 

       370        380        390        400        410        420 
PIFGEVFAAD RQNDAHEFLS LCLVQLKETV QRVNMMWQSE NESGDYYLLR EIFANYTSIN 

       430        440        450        460        470        480 
RTPVCPVTNN FEFELLSSIF CKACGLTVFK REPSRYLSIN IPQGMKDQNM SIQSSLDLFF 

       490        500        510        520        530        540 
RAEELEHRCE RCLYNKSVAL HKFGRLPRVI IVHLKRYSFS ESRIMNKDEQ HIVISKYLRL 

       550        560        570        580        590        600 
SCHCNKNTKP PQPLLPNEHV KNLDLLRPLE ELGSEILKLS SNSGRTSRSK VFPTVNIRSD 

       610        620        630        640        650        660 
KELEVQNGKR VSEVSSGSAQ QEDPGKGANV VRSELTNETE TIKHEKEYVL SDLDSGSISE 

       670        680        690        700        710        720 
ERSQKCQEAE KCNKEALPQS CPKPSSQEQT ENLGKPAVSH TQNGSLSSQG SSDSSKSPGC 

       730        740        750        760        770        780 
NDVFDKAKPT SKVEPQKLNQ KEDNIYRLVS IINHIGNSPN GGHYINDAFD FRKQSWFTYS 

       790        800        810        820 
DLQVTGIQED LVYKARLSTG YVFFYMHNDI FEELLAKEAW STSTSKG 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000047375.
[2]"Gene and alternative splicing annotation with AIR."
Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G.
Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL EDM10949.1.
[3]Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. expand/collapse author list , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL EDM10949.1.
[4]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000047375.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABR06108548 Genomic DNA. No translation available.
AABR06108549 Genomic DNA. No translation available.
AABR06108550 Genomic DNA. No translation available.
AABR06108551 Genomic DNA. No translation available.
AABR06108552 Genomic DNA. No translation available.
AABR06108553 Genomic DNA. No translation available.
CH473991 Genomic DNA. Translation: EDM10949.1.
RefSeqNP_001100418.1. NM_001106948.1.
XP_006257637.1. XM_006257575.1.
UniGeneRn.218652.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000047605; ENSRNOP00000047375; ENSRNOG00000029106.
GeneID302488.
KEGGrno:302488.
UCSCRGD:1563443. rat.

Organism-specific databases

CTD83844.
RGD1563443. Usp26.

Phylogenomic databases

GeneTreeENSGT00440000033542.
KOK11850.
OMADAYDFER.
OrthoDBEOG7HMS09.
PhylomeDBD4A5S1.
TreeFamTF323032.

Family and domain databases

InterProIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view]
PfamPF00443. UCH. 1 hit.
[Graphical view]
PROSITEPS00972. UCH_2_1. 1 hit.
PS00973. UCH_2_2. 1 hit.
PS50235. UCH_2_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio649707.
PROD4A5S1.

Entry information

Entry nameD4A5S1_RAT
AccessionPrimary (citable) accession number: D4A5S1
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 9, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)