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Protein
Submitted name:

COX15 homolog, cytochrome c oxidase assembly protein (Yeast), isoform CRA_a

Gene

Cox15

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-189451. Heme biosynthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
COX15 homolog, cytochrome c oxidase assembly protein (Yeast), isoform CRA_aImported
Submitted name:
Protein Cox15Imported
Gene namesi
Name:Cox15Imported
Synonyms:LOC100911779Imported
ORF Names:rCG_57483Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1312043. Cox15.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei76 – 9621HelicalSequence analysisAdd
BLAST
Transmembranei158 – 17619HelicalSequence analysisAdd
BLAST
Transmembranei188 – 20619HelicalSequence analysisAdd
BLAST
Transmembranei226 – 25025HelicalSequence analysisAdd
BLAST
Transmembranei271 – 29424HelicalSequence analysisAdd
BLAST
Transmembranei330 – 34718HelicalSequence analysisAdd
BLAST
Transmembranei359 – 38325HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

IntActiD4A414. 1 interaction.
STRINGi10116.ENSRNOP00000023215.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2725. Eukaryota.
COG1612. LUCA.
GeneTreeiENSGT00390000002223.
KOiK02259.
OMAiTALIYIV.
OrthoDBiEOG7X9G74.
PhylomeDBiD4A414.
TreeFamiTF105073.

Family and domain databases

HAMAPiMF_01665. HemeA_synth_type2.
InterProiIPR003780. COX15/CtaA_fam.
IPR023754. HemeA_Synthase_type2.
IPR009003. Peptidase_S1_PA.
[Graphical view]
PfamiPF02628. COX15-CtaA. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Complete.

D4A414-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRLFLPPLK ALMGSRNVGL LVPKAASRAQ CGGGSYGGRR PLRPGQYGTI
60 70 80 90 100
TEVALQSGKG TVSLPSRAAE RAVGRWLLVC SGTVAGAVIL GGVTRLTESG
110 120 130 140 150
LSMVDWHLIK EMKPPTSQEE WEAEFQKYQQ FPEFKILNHD MTLAEFKFIW
160 170 180 190 200
YMEYSHRMWG RAVGLAYILP AAYFWRKGWL NRGMKGRVLA LCGLVCFQGL
210 220 230 240 250
LGWYMVKSGL EEKPESYDIP RVSQYRLAAH LGSALILYCG SLWTSLSLLL
260 270 280 290 300
PQHKIPETRQ LLWLRRFAGG TAGLVFLTAL SGAFVAGLDA GLVYNSFPKM
310 320 330 340 350
GESWIPEDLL TFSPILKNVF ENPTMVQFDH RLLGVTSVTA ITMLYFLSRR
360 370 380 390 400
IPLPRRTKMA AVTLLALAYA QVALGISTLL MYVPTPLAAT HQSGSLALLS
410
GALWLMNELR RVPK
Length:414
Mass (Da):45,914
Last modified:April 20, 2010 - v1
Checksum:iB0B751AF5BB889BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099368 Genomic DNA. No translation available.
CH473986 Genomic DNA. Translation: EDL94260.1.
RefSeqiNP_001028871.2. NM_001033699.4.
UniGeneiRn.1309.

Genome annotation databases

EnsembliENSRNOT00000023215; ENSRNOP00000023215; ENSRNOG00000017230.
GeneIDi309391.
KEGGirno:309391.
UCSCiRGD:1312043. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099368 Genomic DNA. No translation available.
CH473986 Genomic DNA. Translation: EDL94260.1.
RefSeqiNP_001028871.2. NM_001033699.4.
UniGeneiRn.1309.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiD4A414. 1 interaction.
STRINGi10116.ENSRNOP00000023215.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000023215; ENSRNOP00000023215; ENSRNOG00000017230.
GeneIDi309391.
KEGGirno:309391.
UCSCiRGD:1312043. rat.

Organism-specific databases

CTDi1355.
RGDi1312043. Cox15.

Phylogenomic databases

eggNOGiKOG2725. Eukaryota.
COG1612. LUCA.
GeneTreeiENSGT00390000002223.
KOiK02259.
OMAiTALIYIV.
OrthoDBiEOG7X9G74.
PhylomeDBiD4A414.
TreeFamiTF105073.

Enzyme and pathway databases

ReactomeiR-RNO-189451. Heme biosynthesis.

Family and domain databases

HAMAPiMF_01665. HemeA_synth_type2.
InterProiIPR003780. COX15/CtaA_fam.
IPR023754. HemeA_Synthase_type2.
IPR009003. Peptidase_S1_PA.
[Graphical view]
PfamiPF02628. COX15-CtaA. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A414_RAT
AccessioniPrimary (citable) accession number: D4A414
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 8, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.