Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Interleukin 7 receptor

Gene

Il7r

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Enzyme and pathway databases

ReactomeiR-RNO-1266695 Interleukin-7 signaling
R-RNO-8856825 Cargo recognition for clathrin-mediated endocytosis
R-RNO-8856828 Clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 7 receptorImported
Submitted name:
Interleukin 7 receptor (Predicted)Imported
Gene namesi
Name:Il7rImported
Synonyms:Il7r_predictedImported
ORF Names:rCG_50960Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1309776 Il7r

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei241 – 264HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501408782121 – 457Sequence analysisAdd BLAST437

Expressioni

Gene expression databases

BgeeiENSRNOG00000058446

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023422

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini131 – 232Fibronectin type-IIIInterPro annotationAdd BLAST102

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGXR Eukaryota
ENOG410YWZG LUCA
GeneTreeiENSGT00510000048500
KOiK05072
OMAiMYEIKVR
OrthoDBiEOG091G0N4J

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR003531 Hempt_rcpt_S_F1_CS
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF00041 fn3, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit
PS01355 HEMATOPO_REC_S_F1, 1 hit

Sequencei

Sequence statusi: Complete.

D4A3X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMALGRAFAI VFCLLQAASG ESGNAQDGDL EDAEPDDHSF WCHSQLEVDG
60 70 80 90 100
NQHSLTCAFN DPDIKTTNLE FQICGALLGI DCLTLNKLRE MYFIKTSKFL
110 120 130 140 150
LIGNSSVCVK LGKMDVICKI LDISTIVKPE APSNLKVVYR KEANDFLVTF
160 170 180 190 200
NTSHSTKKYV TALKHDVAYR PERGESNWTH VYLFHTRTTI LQRKLQPKAV
210 220 230 240 250
YEIKVRSIPN HEYFKGFWSE WSPSSTFETP DSKYQGGWDP VLPSIILLSL
260 270 280 290 300
FSMVLLVILA HVLWKKRIKP VVWPSLPDHK KTLEQLCKKP KKNLNVSFNP
310 320 330 340 350
ESFLDCQIHE VNGIQARDEV ESFLQNDLPP RPGELEKQGH RATVHGANWP
360 370 380 390 400
SEISGSTPET FRRESPLRCL ARNLSTCNTP AFLSSRSPDY REGDGNRSHV
410 420 430 440 450
YQDLLPSSRN TNGTVPQPFP LQSGILIPVS QGQPISTSSV LNQEEAYVTM

SSFYQNK
Length:457
Mass (Da):51,533
Last modified:April 20, 2010 - v1
Checksum:i1686221399272672
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH474048 Genomic DNA Translation: EDL75666.1
RefSeqiNP_001099888.1, NM_001106418.1
XP_017457944.1, XM_017602455.1
UniGeneiRn.224662

Genome annotation databases

EnsembliENSRNOT00000090309; ENSRNOP00000070236; ENSRNOG00000058446
GeneIDi294797
KEGGirno:294797

Similar proteinsi

Entry informationi

Entry nameiD4A3X8_RAT
AccessioniPrimary (citable) accession number: D4A3X8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 25, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health