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Protein

Hexosyltransferase

Gene

B3gnt4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotationSAAS annotationImported, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-2022854. Keratan sulfate biosynthesis.
R-RNO-913709. O-linked glycosylation of mucins.

Names & Taxonomyi

Protein namesi
Recommended name:
HexosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:B3gnt4Imported
Synonyms:B3gnt4_predictedImported
ORF Names:rCG_21387Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1309612. B3gnt4.

Subcellular locationi

  • Golgi apparatus membrane UniRule annotation; Single-pass type II membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatusUniRule annotationSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500816128820 – 349HexosyltransferaseSequence analysisAdd BLAST330

PTM databases

PhosphoSitePlusiD4A3H6.

Expressioni

Gene expression databases

BgeeiENSRNOG00000008544.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011286.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 31 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2287. Eukaryota.
ENOG410ZZ1B. LUCA.
GeneTreeiENSGT00760000118879.
KOiK07971.
OMAiHHAGFKT.
OrthoDBiEOG091G0AXM.
PhylomeDBiD4A3H6.
TreeFamiTF318639.

Family and domain databases

InterProiIPR002659. Glyco_trans_31.
[Graphical view]
PANTHERiPTHR11214. PTHR11214. 1 hit.
PfamiPF01762. Galactosyl_T. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4A3H6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRRLGCVLF CTLVVLLLGC LLFLKERTPA GSSEAHQHFL APPRPHHSQC
60 70 80 90 100
SPNLTVVNTS LSLPSRHRLF LTYRHCRNFS ILLEPSECAR DIFLLLVIKS
110 120 130 140 150
QPAHIEQRAA IRSTWGRGGS WARGRQLKLV FLLGVAGPVP PAQLLAYESW
160 170 180 190 200
QFDDILQWDF AEDFFNLTLK ELHVQRWIAA ACTQAHFILK GDDDVFIHVP
210 220 230 240 250
NVLEFLEGWD PAQDLLVGDV IRLARPNRNT KVKYFIPFSM YRARHYPPYA
260 270 280 290 300
GGGGYVMSQA TVRHLHTAME EAELFPIDDV FVGMCLRKLG VTPIHHAGFK
310 320 330 340
TFGIQQPLNP RDPCLYRGLL LVHRLSPLEM WTMWALVTDE RLECAARKP
Length:349
Mass (Da):39,778
Last modified:April 20, 2010 - v1
Checksum:iFB2DD12F94763F23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036323 Genomic DNA. No translation available.
CH473973 Genomic DNA. Translation: EDM13635.1.
RefSeqiNP_001099408.1. NM_001105938.1.
XP_006249398.1. XM_006249336.3.
UniGeneiRn.218458.

Genome annotation databases

EnsembliENSRNOT00000011286; ENSRNOP00000011286; ENSRNOG00000008544.
GeneIDi288752.
KEGGirno:288752.
UCSCiRGD:1309612. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036323 Genomic DNA. No translation available.
CH473973 Genomic DNA. Translation: EDM13635.1.
RefSeqiNP_001099408.1. NM_001105938.1.
XP_006249398.1. XM_006249336.3.
UniGeneiRn.218458.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011286.

PTM databases

PhosphoSitePlusiD4A3H6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000011286; ENSRNOP00000011286; ENSRNOG00000008544.
GeneIDi288752.
KEGGirno:288752.
UCSCiRGD:1309612. rat.

Organism-specific databases

CTDi79369.
RGDi1309612. B3gnt4.

Phylogenomic databases

eggNOGiKOG2287. Eukaryota.
ENOG410ZZ1B. LUCA.
GeneTreeiENSGT00760000118879.
KOiK07971.
OMAiHHAGFKT.
OrthoDBiEOG091G0AXM.
PhylomeDBiD4A3H6.
TreeFamiTF318639.

Enzyme and pathway databases

ReactomeiR-RNO-2022854. Keratan sulfate biosynthesis.
R-RNO-913709. O-linked glycosylation of mucins.

Gene expression databases

BgeeiENSRNOG00000008544.

Family and domain databases

InterProiIPR002659. Glyco_trans_31.
[Graphical view]
PANTHERiPTHR11214. PTHR11214. 1 hit.
PfamiPF01762. Galactosyl_T. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD4A3H6_RAT
AccessioniPrimary (citable) accession number: D4A3H6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 2, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.