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Protein
Submitted name:

Intraflagellar transport 57

Gene

Ift57

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-5610787. Hedgehog 'off' state.
R-RNO-5620924. Intraflagellar transport.
R-RNO-5632684. Hedgehog 'on' state.

Names & Taxonomyi

Protein namesi
Submitted name:
Intraflagellar transport 57Imported
Submitted name:
Intraflagellar transport 57 homolog (Chlamydomonas) (Predicted)Imported
Gene namesi
Name:Ift57Imported
Synonyms:Ift57_predictedImported
ORF Names:rCG_52737Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 11

Organism-specific databases

RGDi1305947. Ift57.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell projection, Cilium, FlagellumImported

Expressioni

Gene expression databases

BgeeiENSRNOG00000001958.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002684.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili339 – 366Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0972. Eukaryota.
ENOG410XT77. LUCA.
GeneTreeiENSGT00390000006307.
KOiK04638.
OMAiQTYRLDM.
OrthoDBiEOG091G0GDF.
TreeFamiTF106156.

Family and domain databases

InterProiView protein in InterPro
IPR019530. Intra-flagellar_transport_57.
PANTHERiPTHR16011. PTHR16011. 1 hit.
PfamiView protein in Pfam
PF10498. IFT57. 1 hit.

Sequencei

Sequence statusi: Complete.

D4A1V1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAAAVIPP SGLDDGVSRA RGEGAGEAVV ERGPGAAYHM FVVMEDLVEK
60 70 80 90 100
LKLLRYEEEL LRKSNLKPPS RHYFALPTNP GEQFYMFCTL AAWLINKTGR
110 120 130 140 150
AFEQPQEYDD PNATISNILS ELRSFGRTAD FPPSKLKSGY GEHVCYVLDC
160 170 180 190 200
LAEEALKYIG FTWKRPSYPV EELEEETVPE DDAELTLSKV DEEFVEEETD
210 220 230 240 250
NEENFIDLNV LKAQTYRLDT NESAKQEDIL ESTTDAAEWS LEVERVLPQL
260 270 280 290 300
KVTIRTDNKD WRIHVDQMHQ HKSGIESALK ETKGFLDKLH NEISRTLEKI
310 320 330 340 350
GSREKYINNQ LEHLVQEYRG AQAQLSEARE RYQQGNGGVT ERTRLLSEVT
360 370 380 390 400
EELEKVKQEM EEKGSSMTDG TPLVKIKQSL TKLKQETVQM DIRIGVVEHT
410 420
LLQSKLKEKC NMTRDMHAAV TPESAIGFY
Length:429
Mass (Da):48,781
Last modified:April 20, 2010 - v1
Checksum:i9660EE195F604F8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034113 Genomic DNA. No translation available.
AABR07034114 Genomic DNA. No translation available.
AABR07034115 Genomic DNA. No translation available.
CH473967 Genomic DNA. Translation: EDM11101.1.
RefSeqiNP_001100563.1. NM_001107093.1.
UniGeneiRn.63846.

Genome annotation databases

EnsembliENSRNOT00000002684; ENSRNOP00000002684; ENSRNOG00000001958.
GeneIDi303968.
KEGGirno:303968.
UCSCiRGD:1305947. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034113 Genomic DNA. No translation available.
AABR07034114 Genomic DNA. No translation available.
AABR07034115 Genomic DNA. No translation available.
CH473967 Genomic DNA. Translation: EDM11101.1.
RefSeqiNP_001100563.1. NM_001107093.1.
UniGeneiRn.63846.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002684.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000002684; ENSRNOP00000002684; ENSRNOG00000001958.
GeneIDi303968.
KEGGirno:303968.
UCSCiRGD:1305947. rat.

Organism-specific databases

CTDi55081.
RGDi1305947. Ift57.

Phylogenomic databases

eggNOGiKOG0972. Eukaryota.
ENOG410XT77. LUCA.
GeneTreeiENSGT00390000006307.
KOiK04638.
OMAiQTYRLDM.
OrthoDBiEOG091G0GDF.
TreeFamiTF106156.

Enzyme and pathway databases

ReactomeiR-RNO-5610787. Hedgehog 'off' state.
R-RNO-5620924. Intraflagellar transport.
R-RNO-5632684. Hedgehog 'on' state.

Gene expression databases

BgeeiENSRNOG00000001958.

Family and domain databases

InterProiView protein in InterPro
IPR019530. Intra-flagellar_transport_57.
PANTHERiPTHR16011. PTHR16011. 1 hit.
PfamiView protein in Pfam
PF10498. IFT57. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD4A1V1_RAT
AccessioniPrimary (citable) accession number: D4A1V1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 7, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.