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Protein
Submitted name:

Zinc finger protein, multitype 1

Gene

Zfpm1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationPROSITE-ProRule annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-8936459. RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function.
R-RNO-983231. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein, multitype 1Imported
Gene namesi
Name:Zfpm1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi1582810. Zfpm1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD4A168.
PeptideAtlasiD4A168.

Expressioni

Gene expression databases

BgeeiENSRNOG00000043077.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061082.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini249 – 282CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini303 – 332C2H2-typeInterPro annotationAdd BLAST30
Domaini333 – 360C2H2-typeInterPro annotationAdd BLAST28
Domaini586 – 619CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini692 – 725CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini832 – 865CCHC FOG-typeInterPro annotationAdd BLAST34
Domaini959 – 992CCHC FOG-typeInterPro annotationAdd BLAST34

Sequence similaritiesi

Belongs to the FOG (Friend of GATA) family.PROSITE-ProRule annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063823.
InParanoidiD4A168.
OMAiPTHPIII.
OrthoDBiEOG091G00RC.
TreeFamiTF331342.

Family and domain databases

InterProiView protein in InterPro
IPR034731. ZF_CCHC_FOG.
IPR013087. Znf_C2H2_type.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 9 hits.
SUPFAMiSSF57667. SSF57667. 6 hits.
PROSITEiView protein in PROSITE
PS51810. ZF_CCHC_FOG. 5 hits.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.

Sequencei

Sequence statusi: Complete.

D4A168-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRKQSKPR QIKRSLRDME AGEEAKGMDI SPMEQEATAP EAPAIEEPPS
60 70 80 90 100
PPREDVSLPT VSAPPESPDD PEDVEGQELE MRPQDEKKEE KEEESAMASP
110 120 130 140 150
WSGPEELELA LQDGQRCVRA RLSLTEGLSW GPFYGSIQTR ALSPEREEPG
160 170 180 190 200
PALTLMVDES CWLRMLPQAL TEEEANSEIY RKDDALWCRV TKAVPSGGLL
210 220 230 240 250
HVLLVAEPHG TPKHPVQEPE EAGSSGPVHT DIQLLPQQAG MASILATAVI
260 270 280 290 300
NKDVFPCKDC GIWYRSERNL QAHLLYYCAS RQRASSPVSA TEEKPKETYP
310 320 330 340 350
NERICPFPQC RKSCPSASSL EIHMRSHSGE RPFVCLICLS AFTTKANCER
360 370 380 390 400
HLKVHTDTLS GVCHNCGFIS TTRDILYSHL VTNHMVCQPG SKGEIYSPGA
410 420 430 440 450
GHPAAKLPSD SLTGFQQHSL RHSPLVPADK APTPSSGLDS KALAEVTNGE
460 470 480 490 500
TRVPPQNGGS SESPAAPRTI KVEAAEEPEA ARASGPGEPG PQAPSRTPSP
510 520 530 540 550
HSPNPVRVKA ELSSPTPGSS PGPGELTMAG TLFLPQYVFG PDAGTTTVPA
560 570 580 590 600
APQASEILAK MSELVHNRLQ QGAGSSGVAG TPTGLFPGTK GATCFECEIT
610 620 630 640 650
FNNINNFYVH KRLYCSGRRA PEDPPAVRRP KAATGSARAP AGVAAEPDPP
660 670 680 690 700
RSSPGPGPRE EEASGATTPE AETAGRGSEG SQSPGSSVDD AEDDPSRTLC
710 720 730 740 750
EACNIRFSRH ETYTVHKRYY CASRHDPPPR RPPVPTPAPG PAAPALTAPP
760 770 780 790 800
VRTRRRRKLY ELPAAGAPPP AAGPAPVPVV SSPTAELPSS PRPASASAGP
810 820 830 840 850
APTPSPGPVP DGPIDLSKRP RRQTPDTPTA LPALADYHEC TACRVSFHSL
860 870 880 890 900
EAYLAHKKYS CPAAPLRTTA LCPYCPPNGR VRGDLVEHLR QAHGLQVAKP
910 920 930 940 950
AASPGAEPRT AAERAPRDSP DGRAPRSPSP APENTPSDQA DQGARTSCKG
960 970 980 990
PPAPAPAPGG GGGHRYCRLC NIRFSSLSTF IAHKKYYCSS HAAEHVK
Length:997
Mass (Da):106,147
Last modified:July 22, 2015 - v3
Checksum:i44EBCF32175EF8D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07044068 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000068452; ENSRNOP00000061082; ENSRNOG00000043077.

Similar proteinsi

Entry informationi

Entry nameiD4A168_RAT
AccessioniPrimary (citable) accession number: D4A168
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: September 27, 2017
This is version 51 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported