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Protein
Submitted name:

WD repeat domain 3

Gene

Wdr3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat domain 3Imported
Submitted name:
WD repeat domain 3 (Predicted), isoform CRA_cImported
Gene namesi
Name:Wdr3Imported
Synonyms:Wdr3_predictedImported
ORF Names:rCG_52071Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1307480. Wdr3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000019670.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026726.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 711WD_REPEATS_REGIONInterPro annotationAdd BLAST693
Repeati103 – 144WDPROSITE-ProRule annotationAdd BLAST42
Repeati145 – 186WDPROSITE-ProRule annotationAdd BLAST42
Repeati187 – 220WDPROSITE-ProRule annotationAdd BLAST34
Repeati410 – 450WDPROSITE-ProRule annotationAdd BLAST41
Repeati491 – 525WDPROSITE-ProRule annotationAdd BLAST35
Repeati586 – 627WDPROSITE-ProRule annotationAdd BLAST42
Repeati628 – 669WDPROSITE-ProRule annotationAdd BLAST42
Repeati670 – 702WDPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0306. Eukaryota.
ENOG410XR1C. LUCA.
GeneTreeiENSGT00890000139429.
KOiK14556.
OMAiDTMVKWW.
OrthoDBiEOG091G023R.
TreeFamiTF300427.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR020472. G-protein_beta_WD-40_rep.
IPR011047. Quinoprotein_ADH-like_supfam.
IPR007148. SSU_processome_Utp12.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF04003. Utp12. 1 hit.
PF00400. WD40. 7 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 11 hits.
SUPFAMiSSF50998. SSF50998. 2 hits.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 8 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

D4A106-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLTKQYLRY VASAVFGLIG SQKGNIVFVT LRGEKGRYVA VPACEHVFIW
60 70 80 90 100
DLRKGEKILI LQGLKQEVTC LCPSPDGLHL AVGYEDGAIR VFSLLSGEGN
110 120 130 140 150
ITFNGHRAAV TSLKYDQLGG RLASGSKDTD VIIWDVINES GLYRLKGHKD
160 170 180 190 200
AVTQALFLRE RNLLVTSGKD TMVKWWDLDN QHCFKTMVGH RTEVWGLVLV
210 220 230 240 250
SEETRLITGA ADSELRAWDI AYLQEIDDPE EPEPKKIKEC PGIQDTPEAE
260 270 280 290 300
DRTLEADDEK SEDRILSCRK AGSLMREGRD RVVNLAVDKT GRILACHGTD
310 320 330 340 350
SVLEVFCILS KAEVQKKMDK KLKKARKKAR LNSANEEEDP ETSVSMTLQD
360 370 380 390 400
EILRVTKIKT SAKIKSFDLI HSPQGELKAV FLLQNNLVEL YSLSTSLPNP
410 420 430 440 450
QPVRTSRITI GGHRSDVRTL SFSSDNIAVL SAAAESVKIW NRSTLQCIRT
460 470 480 490 500
MPCEYALCSF FVPGDRQVVI GTKTGNMQLY DLASGNLLET IAAHDGALWS
510 520 530 540 550
MSLSPDQRGF VTGGADKAVK FWDFELVTDK NSTQKRLSVK QTRILQLDED
560 570 580 590 600
VLYVCYSPDQ RLLAVSLLDC TVKIFYVDTL KFFLSLYGHK LPVICMDISH
610 620 630 640 650
DGALIATGSA DRNVKIWGLD FGDCHRSLFA HDDSVMHLRF VPKSHLFFTA
660 670 680 690 700
GKDHKIKQWD ADKFEHIQTL EGHHQEIWCL AVSPSGDYVV SASHDKSLRL
710 720 730 740 750
WERTREPLIL EEERELQREA EYEESVAKEE QPAVPGETQG DNYFTGKKTI
760 770 780 790 800
ETVKAAERIM EAIELYREET AKMKEHRAIC RAAGKEVPLP VNPILMAHGN
810 820 830 840 850
ISPSAYVLET FKGIRSSELE EALLVLPFSY VPDILTLFNG FIQTGSDVEL
860 870 880 890 900
LCRCLFFLLR IHFGQITSNQ MLVPVIEKLK ETTISKVRQV QDVIGFNMAG
910 920 930 940
LNYLKRECEA KSEVMFFAEA TSHLEEKKRK RKNRRKMILT LT
Length:942
Mass (Da):106,073
Last modified:April 20, 2010 - v1
Checksum:iD28B6729F1A3C23F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07012693 Genomic DNA. No translation available.
CH474015 Genomic DNA. Translation: EDL85541.1.
CH474015 Genomic DNA. Translation: EDL85542.1.
RefSeqiNP_001101175.1. NM_001107705.1.
UniGeneiRn.12973.

Genome annotation databases

EnsembliENSRNOT00000026726; ENSRNOP00000026726; ENSRNOG00000019670.
GeneIDi310720.
KEGGirno:310720.

Similar proteinsi

Entry informationi

Entry nameiD4A106_RAT
AccessioniPrimary (citable) accession number: D4A106
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: August 30, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported