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Protein
Submitted name:

Protein Zfpm2

Gene

Zfpm2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. nucleic acid binding Source: InterPro
  3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: GO_Central
  4. RNA polymerase II transcription factor binding Source: GO_Central
  5. transcription corepressor activity Source: Ensembl

GO - Biological processi

  1. cell differentiation Source: GO_Central
  2. embryonic organ development Source: Ensembl
  3. heart development Source: GO_Central
  4. in utero embryonic development Source: Ensembl
  5. lung development Source: Ensembl
  6. negative regulation of cell death Source: Ensembl
  7. negative regulation of fat cell differentiation Source: Ensembl
  8. negative regulation of female gonad development Source: Ensembl
  9. negative regulation of transcription from RNA polymerase II promoter Source: GO_Central
  10. outflow tract septum morphogenesis Source: Ensembl
  11. positive regulation of male gonad development Source: Ensembl
  12. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  13. right ventricular cardiac muscle tissue morphogenesis Source: Ensembl
  14. vasculogenesis Source: Ensembl
  15. ventricular septum morphogenesis Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_275619. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Zfpm2Imported
Gene namesi
Name:Zfpm2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1306021. Zfpm2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nucleus Source: RGD
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063823.
InParanoidiD4A0R1.
OMAiDPNKTTC.
OrthoDBiEOG74TWXR.
TreeFamiTF331342.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D4A0R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ELEVFQRDGE RKIQSRQQLP VGTTWGPFAG KMDLNNNSLK TKAQVSMVLT
60 70 80 90 100
AGPKWLLDVT WQGVEDSKNN CIVYSKGGQL WCTTTKAISE GEELIAFVVD
110 120 130 140 150
FDSRLQTASQ MTLTEGMYPA RLLDSIQLLP QQAAMASILP TAIVNKDIFP
160 170 180 190 200
CKSCGIWYRS ERNLQAHLMY YCSGRQREAA PVSEENEDST HQISSLCPFP
210 220 230 240 250
QCTKSFSNAR ALEMHLTSHS GVKMEEFLPP GASLKCTVCS YTADSVINFH
260 270 280 290 300
QHLFSHLTQA AFRCNHCHFG FQTQRELLQH QELHVPGGKL PRESDMEHSP
310 320 330 340 350
SGTEDSLQPA TDLLARSDLS QSQKAMPTKD ASSDTELDKC EKKTQLFLTN
360 370 380 390 400
QRPEMQPAAN KQNFSYTKIK SEPSSPRLAS SPVQPNLGPS FPVGPFLSQF
410 420 430 440 450
AFPQDITMVP QASEILAKMS ELVHRRLRHG SSSYPPVIYS PLMPKGATCF
460 470 480 490 500
ECNITFNNLD NYLVHKKHYC SSRWQQMAKS PEFPSVSEKI PEALSPNTGQ
510 520 530 540 550
TSINLLNPAA HPPDPENPLL QTSCINSSTV LDLIGPNGKG HEKDFSTQAK
560 570 580 590 600
KLPTSNNNDD KINGKPVDVK NPSGPLVDGE SDPNKTTCEA CNITFSRHET
610 620 630 640 650
YMVHKQYYCA TRHDPPLKRS ASNKVPAMQR TMRTRKRRKM YEMCLPEQEQ
660 670 680 690 700
RPPLVQQRFL DVANLSNPCS STQEPTEGLG ECYHPRCDIF PGIVSKHLET
710 720 730 740 750
SLAINKCVPV PKCDTTHSSV SCLEMDVPID LSKKCLSQSE RTTASPKRLL
760 770 780 790 800
DYHECTVCKI SFNKVENYLA HKQNFCPVTA HQRNDLGQLD GKVFPNPESE
810 820 830 840 850
RNSPEVSFER NMIKCEKNGN PKQPSPNGNL FSSHLATLQG LKVFSEAAQL
860 870 880 890 900
IATKEENKHL FLPQCLYPGA IKKTKGADQL SPYYGIKPSD YIAGSLVIHN
910 920 930 940 950
TDVEQNTNTE NESPKGQASS NGCAVPKKDS LPLLPKNRGM VIVNGGLKQD
960 970 980 990 1000
ERPTANPQQE NISQNAQHED GHKSPSWISE NPLAANENVS PGIPCAEEQL
1010 1020 1030 1040 1050
SSIAKGVNGS TQAPSSGKYC RLCDIQFNNL SNFITHKKFY CSSHAAEHVK
Length:1,050
Mass (Da):116,577
Last modified:April 3, 2013 - v2
Checksum:i9956039A24A4F6D0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06050559 Genomic DNA. No translation available.
AABR06050560 Genomic DNA. No translation available.
AABR06050561 Genomic DNA. No translation available.
AABR06050562 Genomic DNA. No translation available.
AABR06050563 Genomic DNA. No translation available.
AABR06050564 Genomic DNA. No translation available.
AABR06050565 Genomic DNA. No translation available.
AABR06050566 Genomic DNA. No translation available.
AABR06050567 Genomic DNA. No translation available.
AABR06050568 Genomic DNA. No translation available.
AABR06050569 Genomic DNA. No translation available.
AABR06050570 Genomic DNA. No translation available.
AABR06050571 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000029419; ENSRNOP00000035072; ENSRNOG00000004109.
UCSCiRGD:1306021. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06050559 Genomic DNA. No translation available.
AABR06050560 Genomic DNA. No translation available.
AABR06050561 Genomic DNA. No translation available.
AABR06050562 Genomic DNA. No translation available.
AABR06050563 Genomic DNA. No translation available.
AABR06050564 Genomic DNA. No translation available.
AABR06050565 Genomic DNA. No translation available.
AABR06050566 Genomic DNA. No translation available.
AABR06050567 Genomic DNA. No translation available.
AABR06050568 Genomic DNA. No translation available.
AABR06050569 Genomic DNA. No translation available.
AABR06050570 Genomic DNA. No translation available.
AABR06050571 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000029419; ENSRNOP00000035072; ENSRNOG00000004109.
UCSCiRGD:1306021. rat.

Organism-specific databases

RGDi1306021. Zfpm2.

Phylogenomic databases

GeneTreeiENSGT00530000063823.
InParanoidiD4A0R1.
OMAiDPNKTTC.
OrthoDBiEOG74TWXR.
TreeFamiTF331342.

Enzyme and pathway databases

ReactomeiREACT_275619. Factors involved in megakaryocyte development and platelet production.

Miscellaneous databases

NextBioi668387.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A0R1_RAT
AccessioniPrimary (citable) accession number: D4A0R1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: April 1, 2015
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.