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D4A0R1

- D4A0R1_RAT

UniProt

D4A0R1 - D4A0R1_RAT

Protein
Submitted name:

Protein Zfpm2

Gene

Zfpm2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 2 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metal ion binding Source: InterPro
    2. nucleic acid binding Source: InterPro
    3. nucleic acid binding transcription factor activity Source: Ensembl
    4. protein binding Source: RGD
    5. transcription corepressor activity Source: Ensembl

    GO - Biological processi

    1. embryonic organ development Source: Ensembl
    2. in utero embryonic development Source: Ensembl
    3. lung development Source: Ensembl
    4. negative regulation of cell death Source: Ensembl
    5. negative regulation of fat cell differentiation Source: Ensembl
    6. negative regulation of female gonad development Source: Ensembl
    7. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    8. outflow tract septum morphogenesis Source: Ensembl
    9. positive regulation of male gonad development Source: Ensembl
    10. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    11. right ventricular cardiac muscle tissue morphogenesis Source: Ensembl
    12. vasculogenesis Source: Ensembl
    13. ventricular septum morphogenesis Source: Ensembl

    Enzyme and pathway databases

    ReactomeiREACT_196232. Factors involved in megakaryocyte development and platelet production.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Zfpm2Imported
    Gene namesi
    Name:Zfpm2Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 7

    Organism-specific databases

    RGDi1306021. Zfpm2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. nucleus Source: RGD

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000063823.
    OMAiDPNKTTC.
    OrthoDBiEOG74TWXR.
    TreeFamiTF331342.

    Family and domain databases

    Gene3Di3.30.160.60. 1 hit.
    InterProiIPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    SMARTiSM00355. ZnF_C2H2. 8 hits.
    [Graphical view]
    PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
    PS50157. ZINC_FINGER_C2H2_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D4A0R1-1 [UniParc]FASTAAdd to Basket

    « Hide

    ELEVFQRDGE RKIQSRQQLP VGTTWGPFAG KMDLNNNSLK TKAQVSMVLT     50
    AGPKWLLDVT WQGVEDSKNN CIVYSKGGQL WCTTTKAISE GEELIAFVVD 100
    FDSRLQTASQ MTLTEGMYPA RLLDSIQLLP QQAAMASILP TAIVNKDIFP 150
    CKSCGIWYRS ERNLQAHLMY YCSGRQREAA PVSEENEDST HQISSLCPFP 200
    QCTKSFSNAR ALEMHLTSHS GVKMEEFLPP GASLKCTVCS YTADSVINFH 250
    QHLFSHLTQA AFRCNHCHFG FQTQRELLQH QELHVPGGKL PRESDMEHSP 300
    SGTEDSLQPA TDLLARSDLS QSQKAMPTKD ASSDTELDKC EKKTQLFLTN 350
    QRPEMQPAAN KQNFSYTKIK SEPSSPRLAS SPVQPNLGPS FPVGPFLSQF 400
    AFPQDITMVP QASEILAKMS ELVHRRLRHG SSSYPPVIYS PLMPKGATCF 450
    ECNITFNNLD NYLVHKKHYC SSRWQQMAKS PEFPSVSEKI PEALSPNTGQ 500
    TSINLLNPAA HPPDPENPLL QTSCINSSTV LDLIGPNGKG HEKDFSTQAK 550
    KLPTSNNNDD KINGKPVDVK NPSGPLVDGE SDPNKTTCEA CNITFSRHET 600
    YMVHKQYYCA TRHDPPLKRS ASNKVPAMQR TMRTRKRRKM YEMCLPEQEQ 650
    RPPLVQQRFL DVANLSNPCS STQEPTEGLG ECYHPRCDIF PGIVSKHLET 700
    SLAINKCVPV PKCDTTHSSV SCLEMDVPID LSKKCLSQSE RTTASPKRLL 750
    DYHECTVCKI SFNKVENYLA HKQNFCPVTA HQRNDLGQLD GKVFPNPESE 800
    RNSPEVSFER NMIKCEKNGN PKQPSPNGNL FSSHLATLQG LKVFSEAAQL 850
    IATKEENKHL FLPQCLYPGA IKKTKGADQL SPYYGIKPSD YIAGSLVIHN 900
    TDVEQNTNTE NESPKGQASS NGCAVPKKDS LPLLPKNRGM VIVNGGLKQD 950
    ERPTANPQQE NISQNAQHED GHKSPSWISE NPLAANENVS PGIPCAEEQL 1000
    SSIAKGVNGS TQAPSSGKYC RLCDIQFNNL SNFITHKKFY CSSHAAEHVK 1050
    Length:1,050
    Mass (Da):116,577
    Last modified:April 3, 2013 - v2
    Checksum:i9956039A24A4F6D0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06050559 Genomic DNA. No translation available.
    AABR06050560 Genomic DNA. No translation available.
    AABR06050561 Genomic DNA. No translation available.
    AABR06050562 Genomic DNA. No translation available.
    AABR06050563 Genomic DNA. No translation available.
    AABR06050564 Genomic DNA. No translation available.
    AABR06050565 Genomic DNA. No translation available.
    AABR06050566 Genomic DNA. No translation available.
    AABR06050567 Genomic DNA. No translation available.
    AABR06050568 Genomic DNA. No translation available.
    AABR06050569 Genomic DNA. No translation available.
    AABR06050570 Genomic DNA. No translation available.
    AABR06050571 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSRNOT00000029419; ENSRNOP00000035072; ENSRNOG00000004109.
    UCSCiRGD:1306021. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06050559 Genomic DNA. No translation available.
    AABR06050560 Genomic DNA. No translation available.
    AABR06050561 Genomic DNA. No translation available.
    AABR06050562 Genomic DNA. No translation available.
    AABR06050563 Genomic DNA. No translation available.
    AABR06050564 Genomic DNA. No translation available.
    AABR06050565 Genomic DNA. No translation available.
    AABR06050566 Genomic DNA. No translation available.
    AABR06050567 Genomic DNA. No translation available.
    AABR06050568 Genomic DNA. No translation available.
    AABR06050569 Genomic DNA. No translation available.
    AABR06050570 Genomic DNA. No translation available.
    AABR06050571 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000029419 ; ENSRNOP00000035072 ; ENSRNOG00000004109 .
    UCSCi RGD:1306021. rat.

    Organism-specific databases

    RGDi 1306021. Zfpm2.

    Phylogenomic databases

    GeneTreei ENSGT00530000063823.
    OMAi DPNKTTC.
    OrthoDBi EOG74TWXR.
    TreeFami TF331342.

    Enzyme and pathway databases

    Reactomei REACT_196232. Factors involved in megakaryocyte development and platelet production.

    Miscellaneous databases

    NextBioi 668387.

    Family and domain databases

    Gene3Di 3.30.160.60. 1 hit.
    InterProi IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    SMARTi SM00355. ZnF_C2H2. 8 hits.
    [Graphical view ]
    PROSITEi PS00028. ZINC_FINGER_C2H2_1. 2 hits.
    PS50157. ZINC_FINGER_C2H2_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD4A0R1_RAT
    AccessioniPrimary (citable) accession number: D4A0R1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 41 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3