Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Euchromatic histone lysine methyltransferase 1

Gene

Ehmt1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • response to fungicide Source: RGD

Enzyme and pathway databases

ReactomeiR-RNO-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-RNO-3214841 PKMTs methylate histone lysines
R-RNO-6804760 Regulation of TP53 Activity through Methylation
R-RNO-8953750 Transcriptional Regulation by E2F6

Names & Taxonomyi

Protein namesi
Submitted name:
Euchromatic histone lysine methyltransferase 1Imported
Gene namesi
Name:Ehmt1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1307588 Ehmt1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiD4A005
PeptideAtlasiD4A005
PRIDEiD4A005

Expressioni

Gene expression databases

BgeeiENSRNOG00000007242
ExpressionAtlasiD4A005 baseline and differential
GenevisibleiD4A005 RN

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063511

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini708 – 945ANK_REP_REGIONInterPro annotationAdd BLAST238
Repeati738 – 770ANKPROSITE-ProRule annotationAdd BLAST33
Repeati771 – 803ANKPROSITE-ProRule annotationAdd BLAST33
Repeati804 – 828ANKPROSITE-ProRule annotationAdd BLAST25
Repeati838 – 870ANKPROSITE-ProRule annotationAdd BLAST33
Repeati904 – 936ANKPROSITE-ProRule annotationAdd BLAST33
Domaini1026 – 1089Pre-SETInterPro annotationAdd BLAST64
Domaini1092 – 1209SETInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili331 – 358Sequence analysisAdd BLAST28

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1082 Eukaryota
COG0666 LUCA
COG2940 LUCA
GeneTreeiENSGT00780000121845
InParanoidiD4A005

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR038035 EHMT1
IPR007728 Pre-SET_dom
IPR001214 SET_dom
PANTHERiPTHR22884:SF364 PTHR22884:SF364, 2 hits
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF05033 Pre-SET, 1 hit
PF00856 SET, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 7 hits
SM00468 PreSET, 1 hit
SM00317 SET, 1 hit
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits
PS50867 PRE_SET, 1 hit
PS50280 SET, 1 hit

Sequencei

Sequence statusi: Complete.

D4A005-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QQAVLAKQET KQDCCMKTEL LREDTLMAAD EGSTEKQAGE TPMAADGETN
60 70 80 90 100
GSCEKSGDIS HPNAPKHTQE NTRASPQEGT NRVSRVAENG VSERDTEVGK
110 120 130 140 150
QNHVTADDFM QTSVIGSNGY FLNKPALQGQ PLRTPNTLNS SLPGHAAKTL
160 170 180 190 200
PGGASKCRTP SALPQTPTTA PTVPGEGSAD TEDRKPTASG TDVRVHRARK
210 220 230 240 250
TMPKSILGLH AASKDHREVQ DHKEPKEDIN RNISECGRQQ LLPTFPALHQ
260 270 280 290 300
SLPQNQCYMA TTKSQTACLP FVLAAAVSRK KKRRMGTYSL VPKKKTKVLK
310 320 330 340 350
QRTVIEMFKS ITHSTVGAKG EKVLDDSALH VNGESLEMDS EEEDSEELED
360 370 380 390 400
EEDRGAEQAA AFPTEDSRTS KESMSETDRA AKSSESSIKK KFLKRRGKTD
410 420 430 440 450
SPWIKPARKR RRRSRKKPSS MLGSEACKSS PGSMEQAALG DSAGYMEVSL
460 470 480 490 500
DSLDLRVRGI LSSQTENEGL ANGPDVLETD GLHEVPLCSC RMETPKSREI
510 520 530 540 550
STLANNQCMA TESVDHELGR CTNSVVKYEL MRPSNKAPLL VLCEDHRGRM
560 570 580 590 600
VKHQCCPGCG YFCTAGNFME CQPESSISHR FHKDCASRVN NASYCPHCGE
610 620 630 640 650
ETSKAKEVTI AKADTTSTVT LAPGQEKSLA AEGRADTTTG SIAGAPEDEK
660 670 680 690 700
SQSTVTQAPE CFDPAGPAGF VRPTSGFSQG PGKETLESAL IALDSEKPKK
710 720 730 740 750
LRFHPKQLYF SARQGELQKV LLMLVDGIDP NFKMEHQSKR SPLHAAAEAG
760 770 780 790 800
HVDICHMLVQ AGANIDTCSE DQRTPLMEAA ENNHLDAVKY LIKAGAQVDP
810 820 830 840 850
KDAEGSTCLH LAAKKGHYDV VQYLLSNGQM DVNCQDDGGW TPMIWATEYK
860 870 880 890 900
HVDLVKLLLS KGSDINIRDN EENICLHWAA FSGCVDIAEI LLAAKCDLHA
910 920 930 940 950
VNIHGDSPLH IAARENRYDC VVLFLSRDSD VTLKNKEGET PLQCASLNSQ
960 970 980 990 1000
VWSALQMSKA LQDSAPDKPV AVEKTVSRDI ARGYERIPIP CVNAVDSELC
1010 1020 1030 1040 1050
PTNYKYVSQN CVTSPMNIDR NITHLQYCVC VDDCSSSTCM CGQLSMRCWY
1060 1070 1080 1090 1100
DKDGRLLPEF NMAEPPLIFE CNHACSCWRN CRNRVVQNGL RARLQLYRTQ
1110 1120 1130 1140 1150
DMGWGVRSLQ DIPLGTFVCE YVGELISDSE ADVREEDSYL FDLDNKDGEV
1160 1170 1180 1190 1200
YCIDARFYGN VSRFINHHCE PNLVPVRVFM SHQDLRFPRI AFFSTRLIQA
1210 1220 1230 1240 1250
GEQLGFDYGE RFWDVKGKLF SCRCGSPKCR HSSAALAQRQ ASAAQEAQEN
1260
GLPDTSSAAA ADPL
Length:1,264
Mass (Da):138,909
Last modified:July 22, 2015 - v3
Checksum:iB0ADC197BA44AA1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07051230 Genomic DNA No translation available.
AABR07051231 Genomic DNA No translation available.
AABR07051232 Genomic DNA No translation available.
AABR07051233 Genomic DNA No translation available.
AABR07051234 Genomic DNA No translation available.
AABR07051235 Genomic DNA No translation available.
AABR07051236 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000066777; ENSRNOP00000063511; ENSRNOG00000007242

Similar proteinsi

Entry informationi

Entry nameiD4A005_RAT
AccessioniPrimary (citable) accession number: D4A005
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: May 23, 2018
This is version 76 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health