Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D4A005

- D4A005_RAT

UniProt

D4A005 - D4A005_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Protein Ehmt1

Gene

Ehmt1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. histone methyltransferase activity (H3-K27 specific) Source: Ensembl
  2. histone methyltransferase activity (H3-K9 specific) Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. DNA methylation Source: Ensembl
  2. embryo development Source: Ensembl
  3. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  4. peptidyl-lysine dimethylation Source: Ensembl
  5. peptidyl-lysine monomethylation Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_194748. Senescence-Associated Secretory Phenotype (SASP).

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Ehmt1Imported
Gene namesi
Name:Ehmt1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 3

Organism-specific databases

RGDi1307588. Ehmt1.

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. cytoplasm Source: Ensembl
  3. nucleus Source: UniProtKB-SubCell
  4. plasma membrane Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation
Contains 7 ANK repeats.UniRule annotation
Contains SET domain.SAAS annotation
Contains pre-SET domain.SAAS annotation

Keywords - Domaini

ANK repeatUniRule annotation, RepeatUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118855.
InParanoidiD4A005.
OMAiSCWRTCK.
OrthoDBiEOG744T8D.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 7 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4A005-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSETDRAAKS SESSIKKKFL KRRGKTDSPW IKPARKRRRR SRKKPSSMLG
60 70 80 90 100
SEACKSSPGS MEQAALGDSA GYMEVSLDSL DLRVRGILSS QTENEGLANG
110 120 130 140 150
PDVLETDGLH EVPLCSCRME TPKSREISTL ANNQCMATES VDHELGRCTN
160 170 180 190 200
SVVKYELMRP SNKAPLLVLC EDHRGRMVKH QCCPGCGYFC TAGNFMECQP
210 220 230 240 250
ESSISHRFHK DCASRVNNAS YCPHCGEETS KAKEVTIAKA DTTSTVTLAP
260 270 280 290 300
GQEKSLAAEG RADTTTGSIA GAPEDEKSQS TVTQAPECFD PAGPAGFVRP
310 320 330 340 350
TSGFSQGPGK ETLESALIAL DSEKPKKLRF HPKQLYFSAR QGELQKVLLM
360 370 380 390 400
LVDGIDPNFK MEHQSKRSPL HAAAEAGHVD ICHMLVQAGA NIDTCSEDQR
410 420 430 440 450
TPLMEAAENN HLDAVKYLIK AGAQVDPKDA EGSTCLHLAA KKGHYDVVQY
460 470 480 490 500
LLSNGQMDVN CQDDGGWTPM IWATEYKHVD LVKLLLSKGS DINIRDNEEN
510 520 530 540 550
ICLHWAAFSG CVDIAEILLA AKCDLHAVNI HGDSPLHIAA RENRYDCVVL
560 570 580 590 600
FLSRDSDVTL KNKEGETPLQ CASLNSQVWS ALQMSKALQD SAPDKPVAVE
610 620 630 640 650
KTVSRDIARG YERIPIPCVN AVDSELCPTN YKYVSQNCVT SPMNIDRNIT
660 670 680 690 700
HLQYCVCVDD CSSSTCMCGQ LSMRCWYDKD GRLLPEFNMA EPPLIFECNH
710 720 730 740 750
ACSCWRNCRN RVVQNGLRAR LQLYRTQDMG WGVRSLQDIP LGTFVCEYVG
760 770 780 790 800
ELISDSEADV REEDSYLFDL DNKDGEVYCI DARFYGNVSR FINHHCEPNL
810 820 830 840 850
VPVRVFMSHQ DLRFPRIAFF STRLIQAGEQ LGFDYGERFW DVKGKLFSCR
860 870 880 890
CGSPKCRHSS AALAQRQASA AQEAQENGLP DTSSAAAADP L
Length:891
Mass (Da):98,427
Last modified:April 3, 2013 - v2
Checksum:iCB9C0D1FBF9B8D55
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06021873 Genomic DNA. No translation available.
AABR06021874 Genomic DNA. No translation available.
AABR06021875 Genomic DNA. No translation available.
AABR06021876 Genomic DNA. No translation available.
AABR06021877 Genomic DNA. No translation available.
AABR06021878 Genomic DNA. No translation available.
AABR06021879 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000066777; ENSRNOP00000063511; ENSRNOG00000007242.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06021873 Genomic DNA. No translation available.
AABR06021874 Genomic DNA. No translation available.
AABR06021875 Genomic DNA. No translation available.
AABR06021876 Genomic DNA. No translation available.
AABR06021877 Genomic DNA. No translation available.
AABR06021878 Genomic DNA. No translation available.
AABR06021879 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000066777 ; ENSRNOP00000063511 ; ENSRNOG00000007242 .

Organism-specific databases

RGDi 1307588. Ehmt1.

Phylogenomic databases

GeneTreei ENSGT00760000118855.
InParanoidi D4A005.
OMAi SCWRTCK.
OrthoDBi EOG744T8D.

Enzyme and pathway databases

Reactomei REACT_194748. Senescence-Associated Secretory Phenotype (SASP).

Miscellaneous databases

NextBioi 678572.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
PRINTSi PR01415. ANKYRIN.
SMARTi SM00248. ANK. 7 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A005_RAT
AccessioniPrimary (citable) accession number: D4A005
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: October 29, 2014
This is version 42 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3