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Protein
Submitted name:

Alpha-adducin

Gene

Add1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-RNO-264870. Caspase-mediated cleavage of cytoskeletal proteins.
R-RNO-5223345. Miscellaneous transport and binding events.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-adducinImported
Gene namesi
Name:Add1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi2041. Add1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiD3ZZ99.
PeptideAtlasiD3ZZ99.
PRIDEiD3ZZ99.

Expressioni

Gene expression databases

BgeeiENSRNOG00000013039.
ExpressionAtlasiD3ZZ99. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018072.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini147 – 329Aldolase_IIInterPro annotationAdd BLAST183

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili618 – 642Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3699. Eukaryota.
COG0235. LUCA.
GeneTreeiENSGT00390000016462.

Family and domain databases

Gene3Di3.40.225.10. 1 hit.
InterProiIPR027766. ADD1.
IPR001303. Aldolase_II/adducin_N.
[Graphical view]
PANTHERiPTHR10672:SF4. PTHR10672:SF4. 3 hits.
PfamiPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTiSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMiSSF53639. SSF53639. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZZ99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGDTRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN
60 70 80 90 100
MMEQKKRVSM ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTA
110 120 130 140 150
SVPNVYPAAP QGGMAALNMS LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA
160 170 180 190 200
AFYRLADLFG WSQLIYNHIT TRVNSEQEHF LIVPFGLLYS EVTASSLVKV
210 220 230 240 250
NLQGDIVDRG STNLGVNQAG FTLHSAIYAA RPDAKCIVHI HTPAGAAVSA
260 270 280 290 300
MKCGLLPISP EALSLGEVAY HDYHGILVDE EEKILIQKNL GPKSKVLILR
310 320 330 340 350
NHGLVSVGES VEEAFFYIHN LVVACEIQVR TLASAGGPDN LVLLDPGKYK
360 370 380 390 400
AKSRSPGTPA GEGSGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL
410 420 430 440 450
RERSKKYSDV EVPASVTGHS FASDGDSGTC SPLRHSFQKQ QREKTRWLNS
460 470 480 490 500
GRGDDASEEG QNGSSPKSKT KPPNAYASCP PHGLLHWTKE DGHRTSTSAV
510 520 530 540 550
PNLFVPLNTN PKEVQEMRNK IREQNLQDIK TAGPQSQVLC GVMMDRSLVQ
560 570 580 590 600
DAPLSDCTET IEGLERTEQT FSPAKSVSFR KGELVTASKA IIEKEYQPHV
610 620 630 640 650
IVSTTGPNPF NTLTDRELEE YRREVERKQK GSEENLDETR EQKEKSPPDQ
660 670
SAVPNTPPST PVKLEGAGDG CAKEYLLP
Length:678
Mass (Da):74,785
Last modified:July 22, 2015 - v3
Checksum:i88C9F43339D5F0D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07015855 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000018340; ENSRNOP00000018340; ENSRNOG00000013039.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07015855 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018072.

Proteomic databases

PaxDbiD3ZZ99.
PeptideAtlasiD3ZZ99.
PRIDEiD3ZZ99.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000018340; ENSRNOP00000018340; ENSRNOG00000013039.

Organism-specific databases

CTDi118.
RGDi2041. Add1.

Phylogenomic databases

eggNOGiKOG3699. Eukaryota.
COG0235. LUCA.
GeneTreeiENSGT00390000016462.

Enzyme and pathway databases

ReactomeiR-RNO-264870. Caspase-mediated cleavage of cytoskeletal proteins.
R-RNO-5223345. Miscellaneous transport and binding events.

Gene expression databases

BgeeiENSRNOG00000013039.
ExpressionAtlasiD3ZZ99. baseline and differential.

Family and domain databases

Gene3Di3.40.225.10. 1 hit.
InterProiIPR027766. ADD1.
IPR001303. Aldolase_II/adducin_N.
[Graphical view]
PANTHERiPTHR10672:SF4. PTHR10672:SF4. 3 hits.
PfamiPF00596. Aldolase_II. 1 hit.
[Graphical view]
SMARTiSM01007. Aldolase_II. 1 hit.
[Graphical view]
SUPFAMiSSF53639. SSF53639. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZZ99_RAT
AccessioniPrimary (citable) accession number: D3ZZ99
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: November 30, 2016
This is version 48 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.