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Protein

Mannosyltransferase

Gene

Pigb

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-162710. Synthesis of glycosylphosphatidylinositol (GPI).

Names & Taxonomyi

Protein namesi
Recommended name:
MannosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:PigbImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1307251. Pigb.

Subcellular locationi

  • Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei51 – 7121HelicalUniRule annotationAdd
BLAST
Transmembranei211 – 23323HelicalUniRule annotationAdd
BLAST
Transmembranei245 – 26420HelicalUniRule annotationAdd
BLAST
Transmembranei297 – 31721HelicalUniRule annotationAdd
BLAST
Transmembranei329 – 34517HelicalUniRule annotationAdd
BLAST
Transmembranei351 – 37020HelicalUniRule annotationAdd
BLAST
Transmembranei377 – 39519HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiD3ZYY8.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 22 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1771. Eukaryota.
ENOG410XYK9. LUCA.
GeneTreeiENSGT00550000075012.
KOiK05286.
OMAiHQKGPIE.

Family and domain databases

InterProiIPR005599. GPI_mannosylTrfase.
[Graphical view]
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiPF03901. Glyco_transf_22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZYY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPETRDHST AFRNLHSSSG EMKLRKRKST QYVIAQEKRS RRRDLLGENT
60 70 80 90 100
YLVLFTIALR IFNCFLVQTS FVPDEYWQSL EVAHHMVFGY GYLTWEWTER
110 120 130 140 150
LRGYTYPLIF ASIYKILHLL GKDSVQLLIW IPRLGQALLS AVADLRLYSL
160 170 180 190 200
TKQLENQEVA RWVFFCQLCS WFTWYCCTRT LTNTMETALT AVALFYYPLE
210 220 230 240 250
GSRSKNSVKY SLLVALACVV RPTALIPWVP LLFRHLYQEQ RKLHLTLHHF
260 270 280 290 300
LPVGFITFSL SLIIDRIFFG QWTLVQFNFL KFNVLQNLGT FYGSHPWHWY
310 320 330 340 350
FSQGFPVVLG THLPFFIHGC FLAPRRLNIL LLAVLWTLLV YSMLGHKEFR
360 370 380 390 400
FIYPVLPFCM VFCGYSLAHL KAWRKAALSF LLLSNVLLAL YTGLVHQRGT
410 420 430 440 450
LDVMSHIQKV CPRGPDPAPA SVFIMMPCHS TPYYSHVHCP LSMRFLQCPP
460 470 480 490 500
DLTGKTQYLD EADTFYLNPL GWLQQEFHSN VSLPTHLVTF NVLEKEIHAF
510 520 530 540
LTSGNYERTA TFFHTHWPER RTGSHIHVYE RRLTSRVSTG GN
Length:542
Mass (Da):63,206
Last modified:April 3, 2013 - v2
Checksum:iD496C96109455A25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142458 Genomic DNA. No translation available.
RefSeqiNP_001101636.3. NM_001108166.3.
UniGeneiRn.231128.

Genome annotation databases

EnsembliENSRNOT00000088562; ENSRNOP00000073341; ENSRNOG00000059622.
GeneIDi315807.
KEGGirno:315807.
UCSCiRGD:1307251. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142458 Genomic DNA. No translation available.
RefSeqiNP_001101636.3. NM_001108166.3.
UniGeneiRn.231128.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiD3ZYY8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000088562; ENSRNOP00000073341; ENSRNOG00000059622.
GeneIDi315807.
KEGGirno:315807.
UCSCiRGD:1307251. rat.

Organism-specific databases

CTDi9488.
RGDi1307251. Pigb.

Phylogenomic databases

eggNOGiKOG1771. Eukaryota.
ENOG410XYK9. LUCA.
GeneTreeiENSGT00550000075012.
KOiK05286.
OMAiHQKGPIE.

Enzyme and pathway databases

ReactomeiR-RNO-162710. Synthesis of glycosylphosphatidylinositol (GPI).

Family and domain databases

InterProiIPR005599. GPI_mannosylTrfase.
[Graphical view]
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiPF03901. Glyco_transf_22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUN-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZYY8_RAT
AccessioniPrimary (citable) accession number: D3ZYY8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: June 8, 2016
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.