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Protein
Submitted name:

Synuclein, alpha interacting protein (Synphilin) (Predicted), isoform CRA_a

Gene

Sncaip

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Synuclein, alpha interacting protein (Synphilin) (Predicted), isoform CRA_aImported
Submitted name:
Synuclein, alpha-interacting proteinImported
Gene namesi
Name:SncaipImported
Synonyms:Sncaip_predictedImported
ORF Names:rCG_46654Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 18

Organism-specific databases

RGDi1309283 Sncaip

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000018254

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiD3ZWQ5, 2 interactors
STRINGi10116.ENSRNOP00000025119

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini348 – 509ANK_REP_REGIONInterPro annotationAdd BLAST162
Repeati455 – 487ANKPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili528 – 548Sequence analysisAdd BLAST21
Coiled coili654 – 674Sequence analysisAdd BLAST21

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00390000001485
KOiK04558
OMAiCRRCDSQ
OrthoDBiEOG091G0QOU
TreeFamiTF329095

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR032027 SNCAIP_SNCA-bd
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF16700 SNCAIP_SNCA_bd, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 4 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZWQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAPEYLDLD EIDFSDDISY SVTSLKTIPA LCRRCDSQNE DRPVSSSSWN
60 70 80 90 100
CGVSTLITNP QKPTGIADVY SKFRPVKRVS PLKHQPETLE SNESDDQKNN
110 120 130 140 150
TVEYQKGGET DQGPQPEELS PEDGVGGLPG KGSEPSQALG ELEHYDLDMD
160 170 180 190 200
EILDVPYIKS SQQLAPLTKV TSEKRILGLC TTVNGLSAKT CPIVSAETST
210 220 230 240 250
PNMAPLCVLS PVKSPHLRKV PSVLRDQHKL PAEESENSPA PGKCGPAFES
260 270 280 290 300
ENHSKDFLNK VFSDPHSRKA EKSGPDCKLR PFRLQTSAAG AKPEEQVNGV
310 320 330 340 350
SWASAQGAEE RTEYLQKVRS ILNIVNEGQI SLLPHLAADN LDKIHDENGN
360 370 380 390 400
NLLHVAASKG HAECLQHLTS LMGEDCLNER NAEQLTPAGL AIKNGQLECV
410 420 430 440 450
RWMVSETEAI AELSCSKDFP SLIHYAGCYG QEKILLWLLQ FMQEQGISLD
460 470 480 490 500
EVDQEGNSAV HVASQHGYLG CIQTLVEYGA NVTMQNHAGE KPSQSAERHG
510 520 530 540 550
HTLCSRYLVV VETCMSLASQ VVKLTKQLKE QTVERVTLQS QLQQLLEAQK
560 570 580 590 600
SEGKSLPSSP SSPSSPASRK SQWKILDADD ESTGKSKLGT QEGIQVLGNL
610 620 630 640 650
SSRARTKGKD EDSDKILRQL LGKEISENVC TQEKLSLEFQ DAQVSSRNSK
660 670 680 690 700
KIPLEKRELK LARLRQLMQR SLSESDTDSN NSEDPKNTPV KRVDRPRPQP
710 720 730 740 750
IVESVENMDS AESLHLMIKK HSVASGRRFP FGMKASKSLD GHSPSPTSES
760 770 780 790 800
SEPDLDSHCP SLGMTPPTQP STEATQCSPD SATAQKVATS PKSALKSPSS
810 820 830 840 850
KRRTSQNSKL RVTFEEPVVQ MEQTSLELNG EKDKERGRAP QRTSESGEQM
860 870 880 890 900
KRPFGTFRSI MESLSGNQNN NNNYQPASQL KTCTLPLTSL GRKTADAKGN
910 920 930 940 950
PVSPASKGKN KAAMYSSCIH LPSNALVEEH LRDYARLNDI KRNTKKTYNV
960
KHIAEPEPKE LFL
Length:963
Mass (Da):105,795
Last modified:April 20, 2010 - v1
Checksum:i0EBCA4B4B1201E7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07032121 Genomic DNA No translation available.
AABR07032122 Genomic DNA No translation available.
AABR07032123 Genomic DNA No translation available.
CH473971 Genomic DNA Translation: EDM14452.1
RefSeqiNP_001100849.1, NM_001107379.1
XP_006254781.1, XM_006254719.2
XP_006254782.1, XM_006254720.3
XP_006254783.1, XM_006254721.3
UniGeneiRn.199043

Genome annotation databases

EnsembliENSRNOT00000025119; ENSRNOP00000025119; ENSRNOG00000018254
ENSRNOT00000082760; ENSRNOP00000068903; ENSRNOG00000018254
GeneIDi307309
KEGGirno:307309
UCSCiRGD:1309283 rat

Similar proteinsi

Entry informationi

Entry nameiD3ZWQ5_RAT
AccessioniPrimary (citable) accession number: D3ZWQ5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health