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D3ZWB7

- D3ZWB7_RAT

UniProt

D3ZWB7 - D3ZWB7_RAT

Protein
Submitted name:

Protein Neu4

Gene

Neu4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-sialidase activity Source: Ensembl

    GO - Biological processi

    1. ganglioside catabolic process Source: Ensembl
    2. glycoprotein catabolic process Source: Ensembl
    3. oligosaccharide catabolic process Source: Ensembl

    Enzyme and pathway databases

    ReactomeiREACT_198596. Glycosphingolipid metabolism.
    REACT_213723. Sialic acid metabolism.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Neu4Imported
    Submitted name:
    Sialidase 4 (Predicted)Imported
    Gene namesi
    Name:Neu4Imported
    Synonyms:Neu4_predictedImported
    ORF Names:rCG_55641Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 9

    Organism-specific databases

    RGDi1308624. Neu4.

    Subcellular locationi

    GO - Cellular componenti

    1. lysosome Source: Ensembl
    2. mitochondrion Source: Ensembl
    3. organelle inner membrane Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000011171.
    KOiK12357.
    OMAiMNPCPVL.
    OrthoDBiEOG7MSMNP.

    Family and domain databases

    Gene3Di2.120.10.10. 2 hits.
    InterProiIPR026946. Sialidase-4.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PTHR10628:SF8. PTHR10628:SF8. 1 hit.
    SUPFAMiSSF50939. SSF50939. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    D3ZWB7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGPAHVPKRT VLFQRERTGL TYRVPALLCV PPRPTLLAFA EQRLSPDDSH    50
    AHRLVLRRGT LTRGSVRWGV LSVLETAVLE EHRSMNPCPV LDEHSGTIFL 100
    FFIAVRGHTP EAVQIATGKN AARLCCVTSC DAGLTWGSVR DLTEEAIGAA 150
    LQDWATFAVG PGHGVQLRSG RLLVPAYTYH VDRRECFGRI CWTSPHSLAF 200
    YSDDHGISWH CGGLVPNLRS GECQLAAVDG DFLYCNARSP LGNRVQALSA 250
    DEGTSFLPGE LVPTLAETAR GCQGSIVGFP APPSIGPQDD RWLASPGNTP 300
    HSPCFDLRVR ESLAEGARGF VEGWASRLLL CYPQSRGPEN HGLEPGPDGE 350
    KTSWSPELPM SSASVRQSST WLLYSHPAGR RARLHMGIYL SRSPLDPHSW 400
    TEPWIIYEGP SGYSDLAFLG PVPGASLAFA CLFESGTRAS YEDISFCLFS 450
    LADVLENVPT GLEISSLRNK PQGHCWPS 478
    Length:478
    Mass (Da):52,045
    Last modified:April 20, 2010 - v1
    Checksum:iE59549DCEDE1C69B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06061641 Genomic DNA. No translation available.
    CH473997 Genomic DNA. Translation: EDL91894.1.
    RefSeqiNP_001101704.1. NM_001108234.1.
    UniGeneiRn.198849.

    Genome annotation databases

    EnsembliENSRNOT00000065533; ENSRNOP00000063883; ENSRNOG00000019031.
    GeneIDi316642.
    KEGGirno:316642.
    UCSCiRGD:1308624. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06061641 Genomic DNA. No translation available.
    CH473997 Genomic DNA. Translation: EDL91894.1 .
    RefSeqi NP_001101704.1. NM_001108234.1.
    UniGenei Rn.198849.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000065533 ; ENSRNOP00000063883 ; ENSRNOG00000019031 .
    GeneIDi 316642.
    KEGGi rno:316642.
    UCSCi RGD:1308624. rat.

    Organism-specific databases

    CTDi 129807.
    RGDi 1308624. Neu4.

    Phylogenomic databases

    GeneTreei ENSGT00390000011171.
    KOi K12357.
    OMAi MNPCPVL.
    OrthoDBi EOG7MSMNP.

    Enzyme and pathway databases

    Reactomei REACT_198596. Glycosphingolipid metabolism.
    REACT_213723. Sialic acid metabolism.

    Miscellaneous databases

    NextBioi 671126.

    Family and domain databases

    Gene3Di 2.120.10.10. 2 hits.
    InterProi IPR026946. Sialidase-4.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    PTHR10628:SF8. PTHR10628:SF8. 1 hit.
    SUPFAMi SSF50939. SSF50939. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD3ZWB7_RAT
    AccessioniPrimary (citable) accession number: D3ZWB7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3