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Protein
Submitted name:

Protein Appl1

Gene

Appl1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-418889. Ligand-independent caspase activation via DCC.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Appl1Imported
Gene namesi
Name:Appl1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1309388. Appl1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiD3ZWA8.
PeptideAtlasiD3ZWA8.
PRIDEiD3ZWA8.

Expressioni

Gene expression databases

BgeeiENSRNOG00000013574.
GenevisibleiD3ZWA8. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018413.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini241 – 339PHInterPro annotationAdd BLAST99
Domaini465 – 601PIDInterPro annotationAdd BLAST137

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili591 – 629Sequence analysisAdd BLAST39

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0521. Eukaryota.
KOG3536. Eukaryota.
ENOG410ZISK. LUCA.
GeneTreeiENSGT00710000106752.
InParanoidiD3ZWA8.
OMAiSDVETMQ.
OrthoDBiEOG091G08AV.
TreeFamiTF328669.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
2.30.29.30. 2 hits.
InterProiIPR027267. AH/BAR-dom.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00640. PID. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 2 hits.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS01179. PID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZWA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQLYQAMHR IYDAQNELSA ATHLTSKLLK EYEKQRFPLG GDDEVMSSTL
60 70 80 90 100
QQFSKVIDEL SSCHAVLSTQ LADAMMFPIS QFKERDLKEI LTLKEVFQIA
110 120 130 140 150
SNDHDAAINR YSRLSKKREN DKVKYEVTED VYTSRKKQHQ TMMHYFCALN
160 170 180 190 200
TLQYKKKIAL LEPLLGYMQA QISFFKMGSE NLNGQLEEFL ANIGTSVQNV
210 220 230 240 250
RREMDGDVET MQQTIEDLEV ASDPLYLPDP DPTKFPVNRN LTRKAGYLNA
260 270 280 290 300
RNKTGLVSST WDRQFYFTQG GNLMSQARGD VAGGLAMDID NCSVMAVDCE
310 320 330 340 350
DRRYCFQITS FDGKKSSILQ AESKKDHEEW ICTINNISKQ IYLSENPEET
360 370 380 390 400
AARVNQSALE AVTPSPSFQQ RHESLRPGGQ SRPPTARTSS SGSLGSESTN
410 420 430 440 450
LAALSLDSLV APDTPIQFDI ISPVCEDQPG QAKAFGQGGR RTNPFGESGG
460 470 480 490 500
STKSETEDSI LHQLFIVRFL GSMEVKSDDH PDVVYETMRQ ILAARAIHNI
510 520 530 540 550
FRMTESHLLV TCDCLKLIDP QTQVTRLTFP LPYVVLYATH QENKRLFGFV
560 570 580 590 600
LRTSGGRSES NLSSVCYIFE SNNEGEKICD SVGLAKQIAL HAELDRRASE
610 620 630 640 650
KQKEIERVKE KQQKELSKQK EIEKDLEEQS RLIAASSRPS QSGSEGQLVL
660 670
SSSQSEESDL GEEGKKRESE A
Length:671
Mass (Da):75,402
Last modified:July 22, 2015 - v3
Checksum:iE4FBA5B5DE096FF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07024511 Genomic DNA. No translation available.
AABR07024512 Genomic DNA. No translation available.
AABR07024513 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000018413; ENSRNOP00000018413; ENSRNOG00000013574.
UCSCiRGD:1309388. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07024511 Genomic DNA. No translation available.
AABR07024512 Genomic DNA. No translation available.
AABR07024513 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018413.

Proteomic databases

PaxDbiD3ZWA8.
PeptideAtlasiD3ZWA8.
PRIDEiD3ZWA8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000018413; ENSRNOP00000018413; ENSRNOG00000013574.
UCSCiRGD:1309388. rat.

Organism-specific databases

RGDi1309388. Appl1.

Phylogenomic databases

eggNOGiKOG0521. Eukaryota.
KOG3536. Eukaryota.
ENOG410ZISK. LUCA.
GeneTreeiENSGT00710000106752.
InParanoidiD3ZWA8.
OMAiSDVETMQ.
OrthoDBiEOG091G08AV.
TreeFamiTF328669.

Enzyme and pathway databases

ReactomeiR-RNO-418889. Ligand-independent caspase activation via DCC.

Gene expression databases

BgeeiENSRNOG00000013574.
GenevisibleiD3ZWA8. RN.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
2.30.29.30. 2 hits.
InterProiIPR027267. AH/BAR-dom.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00640. PID. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 2 hits.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS01179. PID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZWA8_RAT
AccessioniPrimary (citable) accession number: D3ZWA8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: November 2, 2016
This is version 62 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.