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D3ZWA8

- D3ZWA8_RAT

UniProt

D3ZWA8 - D3ZWA8_RAT

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Protein
Submitted name:

Protein Appl1

Gene

Appl1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. cell proliferation Source: Ensembl
  2. regulation of establishment of protein localization to plasma membrane Source: Ensembl
  3. regulation of glucose import Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_234945. Role of DCC in regulating apoptosis.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Appl1Imported
Gene namesi
Name:Appl1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 16

Organism-specific databases

RGDi1309388. Appl1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. endosome membrane Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
  4. NuRD complex Source: Ensembl
  5. vesicle membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3ZWA8.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00710000106752.
InParanoidiD3ZWA8.
OMAiSDVETMQ.
OrthoDBiEOG79PJPK.
TreeFamiTF328669.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
2.30.29.30. 2 hits.
InterProiIPR027267. AH/BAR-dom.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF00640. PID. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS01179. PID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D3ZWA8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
QTRSLLGVFE EDATAISNYM NQLYQAMHRI YDAQNELSAA THLTSKLLKE
60 70 80 90 100
YEKQRFPLGG DDEVMSSTLQ QFSKVIDELS SCHAVLSTQL ADAMMFPISQ
110 120 130 140 150
FKERDLKEIL TLKEVFQIAS NDHDAAINRY SRLSKKREND KVKYEVTEDV
160 170 180 190 200
YTSRKKQHQT MMHYFCALNT LQYKKKIALL EPLLGYMQAQ ISFFKMGSEN
210 220 230 240 250
LNGQLEEFLA NIGTSVQNVR REMDGDVETM QQTIEDLEVA SDPLYLPDPD
260 270 280 290 300
PTKFPVNRNL TRKAGYLNAR NKTGLVSSTW DRQFYFTQGG NLMSQARGDV
310 320 330 340 350
AGGLAMDIDN CSVMAVDCED RRYCFQITSF DGKKSSILQA ESKKDHEEWI
360 370 380 390 400
CTINNISKQI YLSENPEETA ARVNQSALEA VTPSPSFQQR HESLRPGGQS
410 420 430 440 450
RPPTARTSSS GSLGSESTNL AALSLDSLVA PDTPIQFDII SPVCEDQPGQ
460 470 480 490 500
AKAFGQGGRR TNPFGESGGS TKSETEDSIL HQLFIVRFLG SMEVKSDDHP
510 520 530 540 550
DVVYETMRQI LAARAIHNIF RMTESHLLVT CDCLKLIDPQ TQVTRLTFPL
560 570 580 590 600
PYVVLYATHQ ENKRLFGFVL RTSGGRSESN LSSVCYIFES NNEGEKICDS
610 620 630 640 650
VGLAKQIALH AELDRRASEK QKEIERVKEK QQKELSKQKE IEKDLEEQSR
660 670 680 690
LIAASSRPSQ SGSEGQLVLS SSQSEESDLG EEGKKRESEA
Length:690
Mass (Da):77,498
Last modified:April 3, 2013 - v2
Checksum:i7DDC1A474B099BE6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06086214 Genomic DNA. No translation available.
AABR06086215 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000018413; ENSRNOP00000018413; ENSRNOG00000013574.
UCSCiRGD:1309388. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06086214 Genomic DNA. No translation available.
AABR06086215 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D3ZWA8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000018413 ; ENSRNOP00000018413 ; ENSRNOG00000013574 .
UCSCi RGD:1309388. rat.

Organism-specific databases

RGDi 1309388. Appl1.

Phylogenomic databases

GeneTreei ENSGT00710000106752.
InParanoidi D3ZWA8.
OMAi SDVETMQ.
OrthoDBi EOG79PJPK.
TreeFami TF328669.

Enzyme and pathway databases

Reactomei REACT_234945. Role of DCC in regulating apoptosis.

Miscellaneous databases

NextBioi 34025762.
PROi D3ZWA8.

Family and domain databases

Gene3Di 1.20.1270.60. 1 hit.
2.30.29.30. 2 hits.
InterProi IPR027267. AH/BAR-dom.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR006020. PTB/PI_dom.
[Graphical view ]
Pfami PF00640. PID. 1 hit.
[Graphical view ]
SMARTi SM00233. PH. 1 hit.
[Graphical view ]
PROSITEi PS50003. PH_DOMAIN. 1 hit.
PS01179. PID. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZWA8_RAT
AccessioniPrimary (citable) accession number: D3ZWA8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: November 26, 2014
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3