D3ZWA8 (D3ZWA8_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Appl1 Ensembl ENSRNOP00000018413

Gene names

Name:

Appl1 Ensembl ENSRNOP00000018413

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000018413

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	690 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSRNOP00000018413

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell proliferation Inferred from electronic annotation. Source: Compara regulation of establishment of protein localization to plasma membrane Inferred from electronic annotation. Source: Compara regulation of glucose import Inferred from electronic annotation. Source: Compara
Cellular_component	NuRD complex Inferred from electronic annotation. Source: Compara cytosol Inferred from electronic annotation. Source: Compara endosome membrane Inferred from electronic annotation. Source: Compara vesicle membrane Inferred from electronic annotation. Source: Compara
Molecular_function	phospholipid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSRNOP00000018413

Sequences

	Sequence		Length	Mass (Da)
	D3ZWA8 [UniParc]. Last modified April 3, 2013. Version 2. Checksum: 7DDC1A474B099BE6	FASTA	690	77,498
	10 20 30 40 50 60 QTRSLLGVFE EDATAISNYM NQLYQAMHRI YDAQNELSAA THLTSKLLKE YEKQRFPLGG 70 80 90 100 110 120 DDEVMSSTLQ QFSKVIDELS SCHAVLSTQL ADAMMFPISQ FKERDLKEIL TLKEVFQIAS 130 140 150 160 170 180 NDHDAAINRY SRLSKKREND KVKYEVTEDV YTSRKKQHQT MMHYFCALNT LQYKKKIALL 190 200 210 220 230 240 EPLLGYMQAQ ISFFKMGSEN LNGQLEEFLA NIGTSVQNVR REMDGDVETM QQTIEDLEVA 250 260 270 280 290 300 SDPLYLPDPD PTKFPVNRNL TRKAGYLNAR NKTGLVSSTW DRQFYFTQGG NLMSQARGDV 310 320 330 340 350 360 AGGLAMDIDN CSVMAVDCED RRYCFQITSF DGKKSSILQA ESKKDHEEWI CTINNISKQI 370 380 390 400 410 420 YLSENPEETA ARVNQSALEA VTPSPSFQQR HESLRPGGQS RPPTARTSSS GSLGSESTNL 430 440 450 460 470 480 AALSLDSLVA PDTPIQFDII SPVCEDQPGQ AKAFGQGGRR TNPFGESGGS TKSETEDSIL 490 500 510 520 530 540 HQLFIVRFLG SMEVKSDDHP DVVYETMRQI LAARAIHNIF RMTESHLLVT CDCLKLIDPQ 550 560 570 580 590 600 TQVTRLTFPL PYVVLYATHQ ENKRLFGFVL RTSGGRSESN LSSVCYIFES NNEGEKICDS 610 620 630 640 650 660 VGLAKQIALH AELDRRASEK QKEIERVKEK QQKELSKQKE IEKDLEEQSR LIAASSRPSQ 670 680 690 SGSEGQLVLS SSQSEESDLG EEGKKRESEA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000018413.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000018413.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06086214 Genomic DNA. No translation available. AABR06086215 Genomic DNA. No translation available.
IPI	IPI00362434.
3D structure databases
ProteinModelPortal	D3ZWA8.
ModBase	Search...
Protein-protein interaction databases
IntAct	D3ZWA8. 1 interaction.
Proteomic databases
PRIDE	D3ZWA8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000018413; ENSRNOP00000018413; ENSRNOG00000013574.
UCSC	RGD:1309388. rat.
Organism-specific databases
RGD	1309388. Appl1.
Phylogenomic databases
GeneTree	ENSGT00700000104048.
OMA	SDVETMQ.
OrthoDB	EOG4PVNZ2.
Family and domain databases
Gene3D	1.20.1270.60. 1 hit. 2.30.29.30. 2 hits.
InterPro	IPR027267. AH/BAR-dom. IPR011993. PH_like_dom. IPR001849. Pleckstrin_homology. IPR006020. PTyr_interaction_dom. [Graphical view]
Pfam	PF00640. PID. 1 hit. [Graphical view]
SMART	SM00233. PH. 1 hit. [Graphical view]
PROSITE	PS50003. PH_DOMAIN. 1 hit. PS01179. PID. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	34025762.

Entry information

Entry name

D3ZWA8_RAT

Accession

Primary (citable) accession number: D3ZWA8

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 3, 2013
Last modified:	May 1, 2013
This is version 31 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)