Hoxb9

Functionⁱ

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.UniRule annotation

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	185 – 244	HomeoboxPROSITE-ProRule annotationAdd BLAST		60

GO - Molecular functionⁱ

RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

anterior/posterior pattern specification
Source: RGD
Inferred from sequence orthologyⁱ
canonical Wnt signaling pathway
Source: RGD
Inferred from sequence orthologyⁱ
- 19576624
cell chemotaxis
Source: RGD
Inferred from sequence orthologyⁱ
- 19576624
embryonic skeletal system development
Source: RGD
Inferred from sequence orthologyⁱ
mammary gland development
Source: RGD
Inferred from sequence orthologyⁱ
- 9892669
positive regulation of transcription by RNA polymerase II
Source: RGD
Inferred from sequence orthologyⁱ
- 18787068
transcription, DNA-templated Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental proteinUniRule annotation, DNA-bindingUniRule annotationSAAS annotation
Biological process	Transcription, Transcription regulationUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Homeobox proteinUniRule annotation
Gene namesⁱ	Name:Hoxb9Imported Synonyms:Hoxb9_predictedImported ORF Names:rCG_32722Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 10

Organism-specific databases

Rat genome database More...RGDⁱ	1306158. Hoxb9.

RGDⁱ

1306158. Hoxb9.

Keywords - Cellular componentⁱ

NucleusUniRule annotationSAAS annotation

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000007573.

Bgeeⁱ

ENSRNOG00000007573.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000009951.

STRINGⁱ

10116.ENSRNOP00000009951.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	183 – 243	HomeoboxInterPro annotationAdd BLAST		61

Sequence similaritiesⁱ

Belongs to the Abd-B homeobox family.UniRule annotation

Keywords - Domainⁱ

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG0487. Eukaryota. ENOG4111FJP. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000143984.
KEGG Orthology (KO) More...KOⁱ	K09294.
OMAⁱ	RSWLDCA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0H4X.
TreeFamⁱ	TF317819.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086. homeodomain. 1 hit.
InterProⁱ	View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR020479. Homeobox_metazoa. IPR006711. Hox9_activation_N. IPR017112. HXA9/HXB9/HXC9.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit.
PIRSFⁱ	PIRSF037109. Homeobox_Hox9. 1 hit.
PRINTSⁱ	PR00024. HOMEOBOX.
SMARTⁱ	View protein in SMART SM00389. HOX. 1 hit.
SUPFAMⁱ	SSF46689. SSF46689. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZW24-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSISGTLSSY YVDSIISHES EDAPPAKFPS GQYANPRQPG HAEHLDFPSC 
        60         70         80         90        100
SFQPKAPVFG ASWAPLSPHA SGSLPSVYHP YLQPQGAPAA ESRYLRTWLE 
       110        120        130        140        150
PAPRAEAAPG QGQAAVKAEP LLGAPGELLK QGTPEYSLET SAGREAVLSN 
       160        170        180        190        200
QRAGYGDNKI CEGSEDKERP DQTNPSANWL HARSSRKKRC PYTKYQTLEL 
       210        220        230        240        250
EKEFLFNMYL TRDRRHEVAR LLNLSERQVK IWFQNRRMKM KKMNKEQGKE

Length:250

Mass (Da):28,015

Last modified:April 20, 2010 - v1

Checksum:ⁱ2E14D2F9C34D1CE3

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07030395 Genomic DNA. No translation available. CH473948 Genomic DNA. Translation: EDM05795.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001093967.1. NM_001100497.1.
UniGeneⁱ	Rn.198320.

Genome annotation databases

Ensemblⁱ	ENSRNOT00000009951; ENSRNOP00000009951; ENSRNOG00000007573.
GeneIDⁱ	287647.
KEGGⁱ	rno:287647.
UCSC genome browser More...UCSCⁱ	RGD:1306158. rat.

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
D3ZW24	P20615	Mus musculus (Mouse)	250	UniRef100_P20615	Cluster: Homeobox protein Hox-B9	2

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
D3ZW24	P17482 F7BEP8 A0A2K5VDQ0 UPI0003339C54 UPI000C2FA51A G3TN01 UPI00046BC5D9 UPI0003C829A5 UPI0003334B41 A0A286XMP3 +66	Homo sapiens (Human) Callithrix jacchus (White-tufted-ear marmoset) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Echinops telfairi (Lesser hedgehog tenrec) Felis catus (Cat) (Felis silvestris catus) Loxodonta africana (African elephant) Eptesicus fuscus (Big brown bat) (Vespertilio fuscus) Vicugna pacos (Alpaca) (Lama pacos) Jaculus jaculus (Lesser Egyptian jerboa) Cavia porcellus (Guinea pig) And more	250	UniRef90_P17482	Cluster: Homeobox protein Hox-B9	77

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
D3ZW24	P17482 F7BEP8 A0A2K5VDQ0 UPI0003339C54 UPI000C2FA51A G3TN01 UPI0003334B41 UPI0003C829A5 UPI00046BC5D9 A0A286XMP3 +68	Homo sapiens (Human) Callithrix jacchus (White-tufted-ear marmoset) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Echinops telfairi (Lesser hedgehog tenrec) Felis catus (Cat) (Felis silvestris catus) Loxodonta africana (African elephant) Jaculus jaculus (Lesser Egyptian jerboa) Vicugna pacos (Alpaca) (Lama pacos) Eptesicus fuscus (Big brown bat) (Vespertilio fuscus) Cavia porcellus (Guinea pig) And more	250	UniRef50_P17482	Cluster: Homeobox protein Hox-B9	79

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07030395 Genomic DNA. No translation available. CH473948 Genomic DNA. Translation: EDM05795.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001093967.1. NM_001100497.1.
UniGeneⁱ	Rn.198320.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000009951.

STRINGⁱ

10116.ENSRNOP00000009951.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000009951; ENSRNOP00000009951; ENSRNOG00000007573.
GeneIDⁱ	287647.
KEGGⁱ	rno:287647.
UCSC genome browser More...UCSCⁱ	RGD:1306158. rat.

Organism-specific databases

CTDⁱ	3219.
Rat genome database More...RGDⁱ	1306158. Hoxb9.

Phylogenomic databases

eggNOGⁱ	KOG0487. Eukaryota. ENOG4111FJP. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000143984.
KEGG Orthology (KO) More...KOⁱ	K09294.
OMAⁱ	RSWLDCA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0H4X.
TreeFamⁱ	TF317819.

Gene expression databases

Bgeeⁱ	ENSRNOG00000007573.

Bgeeⁱ

ENSRNOG00000007573.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086. homeodomain. 1 hit.
InterProⁱ	View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR020479. Homeobox_metazoa. IPR006711. Hox9_activation_N. IPR017112. HXA9/HXB9/HXC9.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit.
PIRSFⁱ	PIRSF037109. Homeobox_Hox9. 1 hit.
PRINTSⁱ	PR00024. HOMEOBOX.
SMARTⁱ	View protein in SMART SM00389. HOX. 1 hit.
SUPFAMⁱ	SSF46689. SSF46689. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZW24_RAT
Accessionⁱ	D3ZW24Primary (citable) accession number: D3ZW24
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	March 28, 2018
	This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZW24 (D3ZW24_RAT)

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Homeobox protein

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Mitochondrion

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ