UniProtKB - D3ZW24 (D3ZW24_RAT)
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Protein
Homeobox protein
Gene
Hoxb9
Organism
Rattus norvegicus (Rat)
Status
Functioni
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 185 – 244 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
GO - Biological processi
- anterior/posterior pattern specification Source: RGD
- canonical Wnt signaling pathway Source: RGD
- cell chemotaxis Source: RGD
- embryonic skeletal system development Source: RGD
- mammary gland development Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- transcription, DNA-templated Source: UniProtKB-UniRule
Keywordsi
Molecular function | Developmental proteinUniRule annotation, DNA-bindingUniRule annotationSAAS annotation |
Biological process | Transcription, Transcription regulationUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Homeobox proteinUniRule annotation |
Gene namesi | ORF Names:rCG_32722Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1306158. Hoxb9. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 183 – 243 | HomeoboxInterPro annotationAdd BLAST | 61 |
Sequence similaritiesi
Belongs to the Abd-B homeobox family.UniRule annotation
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationSAAS annotationPhylogenomic databases
eggNOGi | KOG0487. Eukaryota. ENOG4111FJP. LUCA. |
GeneTreei | ENSGT00910000143984. |
KOi | K09294. |
OMAi | RSWLDCA. |
OrthoDBi | EOG091G0H4X. |
TreeFami | TF317819. |
Family and domain databases
CDDi | cd00086. homeodomain. 1 hit. |
InterProi | View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR020479. Homeobox_metazoa. IPR006711. Hox9_activation_N. IPR017112. HXA9/HXB9/HXC9. |
Pfami | View protein in Pfam PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit. |
PIRSFi | PIRSF037109. Homeobox_Hox9. 1 hit. |
PRINTSi | PR00024. HOMEOBOX. |
SMARTi | View protein in SMART SM00389. HOX. 1 hit. |
SUPFAMi | SSF46689. SSF46689. 1 hit. |
PROSITEi | View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
D3ZW24-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSISGTLSSY YVDSIISHES EDAPPAKFPS GQYANPRQPG HAEHLDFPSC
60 70 80 90 100
SFQPKAPVFG ASWAPLSPHA SGSLPSVYHP YLQPQGAPAA ESRYLRTWLE
110 120 130 140 150
PAPRAEAAPG QGQAAVKAEP LLGAPGELLK QGTPEYSLET SAGREAVLSN
160 170 180 190 200
QRAGYGDNKI CEGSEDKERP DQTNPSANWL HARSSRKKRC PYTKYQTLEL
210 220 230 240 250
EKEFLFNMYL TRDRRHEVAR LLNLSERQVK IWFQNRRMKM KKMNKEQGKE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07030395 Genomic DNA. No translation available. CH473948 Genomic DNA. Translation: EDM05795.1. |
RefSeqi | NP_001093967.1. NM_001100497.1. |
UniGenei | Rn.198320. |
Genome annotation databases
Ensembli | ENSRNOT00000009951; ENSRNOP00000009951; ENSRNOG00000007573. |
GeneIDi | 287647. |
KEGGi | rno:287647. |
UCSCi | RGD:1306158. rat. |
Similar proteinsi
Entry informationi
Entry namei | D3ZW24_RAT | |
Accessioni | D3ZW24Primary (citable) accession number: D3ZW24 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | March 28, 2018 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |