Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3ZU00

- D3ZU00_RAT

UniProt

D3ZU00 - D3ZU00_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Prospero-related homeobox 1 (Predicted)

Gene

Prox1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: Ensembl
  2. sequence-specific DNA binding Source: Ensembl
  3. transcription corepressor activity Source: Ensembl
  4. transcription regulatory region DNA binding Source: Ensembl

GO - Biological processi

  1. aorta smooth muscle tissue morphogenesis Source: Ensembl
  2. atrial cardiac muscle tissue morphogenesis Source: Ensembl
  3. brain development Source: RGD
  4. cell fate determination Source: Ensembl
  5. cerebellar granule cell differentiation Source: Ensembl
  6. dentate gyrus development Source: Ensembl
  7. embryonic retina morphogenesis in camera-type eye Source: Ensembl
  8. endocardium formation Source: Ensembl
  9. hepatocyte cell migration Source: Ensembl
  10. hepatocyte differentiation Source: Ensembl
  11. hepatocyte proliferation Source: Ensembl
  12. inner ear development Source: Ensembl
  13. kidney development Source: Ensembl
  14. lens fiber cell morphogenesis Source: Ensembl
  15. liver development Source: RGD
  16. lung development Source: Ensembl
  17. lymphangiogenesis Source: Ensembl
  18. negative regulation of bile acid biosynthetic process Source: Ensembl
  19. negative regulation of cell proliferation Source: Ensembl
  20. negative regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
  21. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  22. negative regulation of viral genome replication Source: Ensembl
  23. neuronal stem cell maintenance Source: Ensembl
  24. optic placode formation involved in camera-type eye formation Source: Ensembl
  25. pancreas development Source: Ensembl
  26. positive regulation of cell cycle checkpoint Source: Ensembl
  27. positive regulation of cyclin-dependent protein serine/threonine kinase activity Source: Ensembl
  28. positive regulation of endothelial cell migration Source: Ensembl
  29. positive regulation of endothelial cell proliferation Source: Ensembl
  30. positive regulation of forebrain neuron differentiation Source: Ensembl
  31. positive regulation of heart growth Source: Ensembl
  32. positive regulation of neural precursor cell proliferation Source: Ensembl
  33. positive regulation of sarcomere organization Source: Ensembl
  34. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  35. regulation of transcription involved in lymphatic endothelial cell fate commitment Source: Ensembl
  36. response to nutrient levels Source: RGD
  37. skeletal muscle thin filament assembly Source: Ensembl
  38. venous blood vessel morphogenesis Source: Ensembl
  39. ventricular cardiac muscle tissue morphogenesis Source: Ensembl
  40. ventricular cardiac myofibril assembly Source: Ensembl
  41. ventricular septum morphogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Prospero-related homeobox 1 (Predicted)Imported
Submitted name:
Protein Prox1Imported
Gene namesi
Name:Prox1Imported
Synonyms:Prox1_predictedImported
ORF Names:rCG_20423Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 13

Organism-specific databases

RGDi1306890. Prox1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nucleus Source: RGD
Complete GO annotation...

Family & Domainsi

Keywords - Domaini

HomeoboxImported

Phylogenomic databases

GeneTreeiENSGT00530000063507.
OMAiQECLSPF.
OrthoDBiEOG7MSMNK.
TreeFamiTF316638.

Family and domain databases

InterProiIPR007738. Prox1.
[Graphical view]
PANTHERiPTHR12198. PTHR12198. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZU00-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPDHDSTALL SRQTKRRRVD IGVKRTVGTA SAFFAKARAT FFSAMNPQGS
60 70 80 90 100
EQDVEYSVVQ HADGEKSNVL RKLLKRANSY EDAMMPFPGA TIISQLLKNN
110 120 130 140 150
MNKNGGTEPS FQASGLSSTG SEVHQEDICS NSSRDSPPEC LSPFGRPTMS
160 170 180 190 200
QFDVDRLCDE HLRAKRARVE NIIRGMSHSP SVALRGNENE REMAPQSVSP
210 220 230 240 250
RESYRENKRK QKLPQQQQQS FQQLVSARKE QKREERRQLK QQLEDMQKQL
260 270 280 290 300
RQLQEKFYQV YDSTDSENDE DGDLSEDSMR SEILDARAQD SVGRSDNEMC
310 320 330 340 350
ELDPGQFIDR ARALIREQEM AENKPKREGS NKERDHGPNS LQPEGKHLAE
360 370 380 390 400
TLKQELNTAM SQVVDTVVKV FSAKPSRQVP QVFPPLQIPQ ARFAVNGENH
410 420 430 440 450
NFHTANQRLQ CFGDVIIPNP LDTFGNVQMP SSTDQTEALP LVVRKNSSEQ
460 470 480 490 500
SASGPATGGH HQPLHQSPLS ATAGFTTPSF RHPFPLPLMA YPFQSPLGAP
510 520 530 540 550
SGSFSGKDRA SPESLDLTRD TTSLRTKMSS HHLSHHPCSP AHPPSTAEGL
560 570 580
SLSLIKSECG DLQDMSDISP YSGSAMKGYH PIT
Length:583
Mass (Da):64,845
Last modified:April 20, 2010 - v1
Checksum:iBB926DE9CEECA908
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06076839 Genomic DNA. No translation available.
AABR06076840 Genomic DNA. No translation available.
AABR06076841 Genomic DNA. No translation available.
AABR06076842 Genomic DNA. No translation available.
AABR06076843 Genomic DNA. No translation available.
AABR06076844 Genomic DNA. No translation available.
CH473985 Genomic DNA. Translation: EDL94973.1.
RefSeqiNP_001100671.1. NM_001107201.1.
UniGeneiRn.26557.

Genome annotation databases

EnsembliENSRNOT00000004905; ENSRNOP00000004905; ENSRNOG00000003694.
GeneIDi305066.
KEGGirno:305066.
UCSCiRGD:1306890. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06076839 Genomic DNA. No translation available.
AABR06076840 Genomic DNA. No translation available.
AABR06076841 Genomic DNA. No translation available.
AABR06076842 Genomic DNA. No translation available.
AABR06076843 Genomic DNA. No translation available.
AABR06076844 Genomic DNA. No translation available.
CH473985 Genomic DNA. Translation: EDL94973.1 .
RefSeqi NP_001100671.1. NM_001107201.1.
UniGenei Rn.26557.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000004905 ; ENSRNOP00000004905 ; ENSRNOG00000003694 .
GeneIDi 305066.
KEGGi rno:305066.
UCSCi RGD:1306890. rat.

Organism-specific databases

CTDi 5629.
RGDi 1306890. Prox1.

Phylogenomic databases

GeneTreei ENSGT00530000063507.
OMAi QECLSPF.
OrthoDBi EOG7MSMNK.
TreeFami TF316638.

Miscellaneous databases

NextBioi 654030.

Family and domain databases

InterProi IPR007738. Prox1.
[Graphical view ]
PANTHERi PTHR12198. PTHR12198. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZU00_RAT
AccessioniPrimary (citable) accession number: D3ZU00
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 1, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3