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Protein
Submitted name:

ERCC excision repair 5, endonuclease

Gene

Ercc5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-5696395 Formation of Incision Complex in GG-NER
R-RNO-5696400 Dual Incision in GG-NER
R-RNO-6782135 Dual incision in TC-NER

Names & Taxonomyi

Protein namesi
Submitted name:
ERCC excision repair 5, endonucleaseImported
Gene namesi
Name:Ercc5Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1586176 Ercc5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiD3ZTV2

Expressioni

Gene expression databases

BgeeiENSRNOG00000022812
ExpressionAtlasiD3ZTV2 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 98XPGNInterPro annotationAdd BLAST98
Domaini774 – 843XPGIInterPro annotationAdd BLAST70

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili730 – 753Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2520 Eukaryota
COG0258 LUCA
GeneTreeiENSGT00640000091542
OMAiAIDSSIW
OrthoDBiEOG091G0OMB
TreeFamiTF101235

Family and domain databases

InterProiView protein in InterPro
IPR036279 5-3_exonuclease_C_sf
IPR029060 PIN-like_dom_sf
IPR006086 XPG-I_dom
IPR006084 XPG/Rad2
IPR001044 XPG/Rad2_eukaryotes
IPR019974 XPG_CS
IPR006085 XPG_DNA_repair_N
PfamiView protein in Pfam
PF00867 XPG_I, 1 hit
PF00752 XPG_N, 1 hit
PRINTSiPR00853 XPGRADSUPER
PR00066 XRODRMPGMNTG
SMARTiView protein in SMART
SM00484 XPGI, 1 hit
SM00485 XPGN, 1 hit
SUPFAMiSSF47807 SSF47807, 1 hit
SSF88723 SSF88723, 2 hits
TIGRFAMsiTIGR00600 rad2, 1 hit
PROSITEiView protein in PROSITE
PS00841 XPG_1, 1 hit
PS00842 XPG_2, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZTV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVQGLWKLL ECSGRPVSPE ALEGKVLAVD ISIWLNQALK GVRDRHGNAI
60 70 80 90 100
ENAHLLTLFH RLCKLLFFRI RPIFVFDGDA PLLKKQTLAK RRQKKDSASI
110 120 130 140 150
DSRKTTEKLL KTFLKRQALK TAFRSKRNEV LPSLTQVQRE DDIYVLPPLQ
160 170 180 190 200
EEEKHSSEEE DEKQWQARMD QKQALQEEFF HNPHAIDIES EDFSSLPPEV
210 220 230 240 250
KHEILTDMKE FTKRRRTLFE AMPEESNDFS QYQLKGLLKK NYLNQHIENV
260 270 280 290 300
QKEMNQEHSG QIQRQYEDEG GFLKEVESRR VVAEDTSHYI LIKGIQGKKV
310 320 330 340 350
VDVDLESLPS SSKEHSVSFN LKSSPYEKVK PESEPEATPP SPRTLHAIQV
360 370 380 390 400
AMLGGSSEEE PESGEGGQSK ERSAWATADA GSISPQTCAA IQRALDDDEE
410 420 430 440 450
ERMCASSDNL AVEMLLGNGL KQEHADEVVV KGGGVPLDTA SLLPSVTEVE
460 470 480 490 500
ECVASASNDK EQTASTHASS TACHPGEVPK ETVSPAHVVS EASQISSECE
510 520 530 540 550
VAGRPVPLPS AFIETPCSYA SGVLSERELT LAPPIRTHSH QRTSIDPEEP
560 570 580 590 600
ELQNGLCPPK NTCNSSHLSS DDETEGGQNP ASKAGSTVHV PSEAVGNVEN
610 620 630 640 650
VSSSNAEEHG DFQKTIQLWE MPEAAARELI SAPESLGPVE MESEESESDG
660 670 680 690 700
SFIEVQSVIS NDELQIESSE ISKHLSEKDA EEPKETLEEG SPRNTECLLQ
710 720 730 740 750
DSSDIKAMKE HRKEDRGAED SPDEWQDVNL EELDALESNL LAEQNSLEAQ
760 770 780 790 800
KQQQDRIAAS VTGQMFLESQ ELLRLFGIPY IQAPMEAEAQ CAILDLTDQT
810 820 830 840 850
SGTITDDSDI WLFGARHVYK NFFNKNKFVE YYQYVDFYNQ LGLDRNKLTT
860 870 880 890 900
WLIYWAVIIY TEGIPTVGWT AMEILQIPGR GLDPLLKFSE WWHKAQNNKK
910 920 930 940 950
AAENPYDTKV KKKLRKLQLT PGFPNPAVAD AYLRPVVDDS RGSFLWGKPD
960 970 980 990 1000
VDKISTFCQR YFGWNRMKTD ESLYPVLKQL NAHQTQLRID SFFRLAQQEK
1010 1020 1030 1040 1050
QDAKHIKSHR LSRAVTCMLR KEREETAGEL KKVPETLDKA NGKTQKRSQP
1060 1070 1080 1090 1100
NTRETSVPKR RRPSGNGGFL GNSYLSELPQ ESSSEEAEGS SMISAQQRRA
1110 1120 1130 1140 1150
AESSNVSCSD LPDLVRDTPH GRDGYMSTSS SSEDGEDKAK AVLVTARPVF
1160
GKKKGKLKNM RRRKKK
Length:1,166
Mass (Da):130,614
Last modified:July 22, 2015 - v2
Checksum:i35CCFF1523F95A8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07067520 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000059349; ENSRNOP00000056107; ENSRNOG00000022812

Similar proteinsi

Entry informationi

Entry nameiD3ZTV2_RAT
AccessioniPrimary (citable) accession number: D3ZTV2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: May 23, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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