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Protein
Submitted name:

Protein Bmp8a

Gene

Bmp8a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Growth factorUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Bmp8aImported
Submitted name:
RCG31105Imported
Gene namesi
Name:Bmp8aImported
ORF Names:rCG_31105Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1585858. Bmp8a.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500816117922 – 399Sequence analysisAdd BLAST378

Keywords - PTMi

Disulfide bondSAAS annotation

PTM databases

PhosphoSitePlusiD3ZTI5.

Expressioni

Gene expression databases

BgeeiENSRNOG00000030155.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049643.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini265 – 399TGF_BETA_2InterPro annotationAdd BLAST135

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3900. Eukaryota.
ENOG410XT8Z. LUCA.
GeneTreeiENSGT00760000118883.
KOiK16622.
OMAiGREKKEM.
OrthoDBiEOG091G0K7Z.
PhylomeDBiD3ZTI5.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR002405. Inhibin_asu.
IPR001839. TGF-b_C.
IPR001111. TGF-b_N.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
[Graphical view]
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiPF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
[Graphical view]
PRINTSiPR00669. INHIBINA.
SMARTiSM00204. TGFB. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZTI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRPGPLWL LGLALCALGG GHGPRPPHTC PQRRLGARER RDMQREILAV
60 70 80 90 100
LGLPGRPRPR APPAAARQPA SAPLFMLDLY HAMTDDDDGG PPQAHLGRAD
110 120 130 140 150
LVMSFVNMVE RDRTLGYQEP HWKEFHFDLT QIPAGEAVTA AEFRIYKEPS
160 170 180 190 200
THPPNTTLHI SMFEVVQERS NRESDLFFLD LQTLRSGDEG WLVLDITAAS
210 220 230 240 250
DRWLLNHNKD LGLRLYVETE DGHSLDPGLA GLLGQTAPRS RQPFMVTFFR
260 270 280 290 300
ASSSPVRTPR AVRPLKRRQP KKTNELPHPN KLPGIFDDGH GSRGREVCRR
310 320 330 340 350
HELYVSFRDL GWLDWVIAPQ GYSAYYCEGE CAFPLDSCMN ATNHAILQSL
360 370 380 390
VHLMKPDVVP KACCAPTKLS ATSVLYYDSS NNVILRKHRN MVVKACGCH
Length:399
Mass (Da):44,683
Last modified:April 20, 2010 - v1
Checksum:iEC73F2667C91058A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114512 Genomic DNA. No translation available.
CH473968 Genomic DNA. Translation: EDL80378.1.
RefSeqiNP_001102902.1. NM_001109432.1.
UniGeneiRn.126011.

Genome annotation databases

EnsembliENSRNOT00000045922; ENSRNOP00000049643; ENSRNOG00000030155.
GeneIDi680931.
KEGGirno:680931.
UCSCiRGD:1585858. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114512 Genomic DNA. No translation available.
CH473968 Genomic DNA. Translation: EDL80378.1.
RefSeqiNP_001102902.1. NM_001109432.1.
UniGeneiRn.126011.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049643.

PTM databases

PhosphoSitePlusiD3ZTI5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000045922; ENSRNOP00000049643; ENSRNOG00000030155.
GeneIDi680931.
KEGGirno:680931.
UCSCiRGD:1585858. rat.

Organism-specific databases

CTDi353500.
RGDi1585858. Bmp8a.

Phylogenomic databases

eggNOGiKOG3900. Eukaryota.
ENOG410XT8Z. LUCA.
GeneTreeiENSGT00760000118883.
KOiK16622.
OMAiGREKKEM.
OrthoDBiEOG091G0K7Z.
PhylomeDBiD3ZTI5.

Gene expression databases

BgeeiENSRNOG00000030155.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR002405. Inhibin_asu.
IPR001839. TGF-b_C.
IPR001111. TGF-b_N.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
[Graphical view]
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiPF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
[Graphical view]
PRINTSiPR00669. INHIBINA.
SMARTiSM00204. TGFB. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZTI5_RAT
AccessioniPrimary (citable) accession number: D3ZTI5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 30, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.