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Protein
Submitted name:

Bone morphogenetic protein 8a

Gene

Bmp8a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGrowth factorUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Bone morphogenetic protein 8aImported
Submitted name:
RCG31105Imported
Gene namesi
Name:Bmp8aImported
ORF Names:rCG_31105Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1585858. Bmp8a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501082958222 – 399Sequence analysisAdd BLAST378

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000030155.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049643.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini265 – 399TGF_BETA_2InterPro annotationAdd BLAST135

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3900. Eukaryota.
ENOG410XT8Z. LUCA.
GeneTreeiENSGT00760000118883.
KOiK16622.
OMAiMKPEAVP.
OrthoDBiEOG091G0K7Z.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiView protein in InterPro
IPR029034. Cystine-knot_cytokine.
IPR001839. TGF-b_C.
IPR001111. TGF-b_propeptide.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiView protein in Pfam
PF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
SMARTiView protein in SMART
SM00204. TGFB. 1 hit.
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiView protein in PROSITE
PS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZTI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRPGPLWL LGLALCALGG GHGPRPPHTC PQRRLGARER RDMQREILAV
60 70 80 90 100
LGLPGRPRPR APPAAARQPA SAPLFMLDLY HAMTDDDDGG PPQAHLGRAD
110 120 130 140 150
LVMSFVNMVE RDRTLGYQEP HWKEFHFDLT QIPAGEAVTA AEFRIYKEPS
160 170 180 190 200
THPPNTTLHI SMFEVVQERS NRESDLFFLD LQTLRSGDEG WLVLDITAAS
210 220 230 240 250
DRWLLNHNKD LGLRLYVETE DGHSLDPGLA GLLGQTAPRS RQPFMVTFFR
260 270 280 290 300
ASSSPVRTPR AVRPLKRRQP KKTNELPHPN KLPGIFDDGH GSRGREVCRR
310 320 330 340 350
HELYVSFRDL GWLDWVIAPQ GYSAYYCEGE CAFPLDSCMN ATNHAILQSL
360 370 380 390
VHLMKPDVVP KACCAPTKLS ATSVLYYDSS NNVILRKHRN MVVKACGCH
Length:399
Mass (Da):44,683
Last modified:April 20, 2010 - v1
Checksum:iEC73F2667C91058A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114512 Genomic DNA. No translation available.
CH473968 Genomic DNA. Translation: EDL80378.1.
RefSeqiNP_001102902.1. NM_001109432.1.
UniGeneiRn.126011.

Genome annotation databases

EnsembliENSRNOT00000045922; ENSRNOP00000049643; ENSRNOG00000030155.
GeneIDi680931.
KEGGirno:680931.
UCSCiRGD:1585858. rat.

Similar proteinsi

Entry informationi

Entry nameiD3ZTI5_RAT
AccessioniPrimary (citable) accession number: D3ZTI5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: August 30, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported