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D3ZS31

- D3ZS31_RAT

UniProt

D3ZS31 - D3ZS31_RAT

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Protein
Submitted name:

Lethal(2) giant larvae protein homolog 1

Gene

Rgl1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

GO - Biological processi

  1. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factorSAAS annotation

Enzyme and pathway databases

ReactomeiREACT_196408. PPARA activates gene expression.

Names & Taxonomyi

Protein namesi
Submitted name:
Lethal(2) giant larvae protein homolog 1Imported
Submitted name:
Ral guanine nucleotide dissociation stimulator,-like 1 (Predicted), isoform CRA_aImported
Gene namesi
Name:Rgl1Imported
Synonyms:Rgl1_predictedImported
ORF Names:rCG_46416Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 13

Organism-specific databases

RGDi1308947. Rgl1.

Family & Domainsi

Sequence similaritiesi

Contains N-terminal Ras-GEF domain.SAAS annotation
Contains Ras-GEF domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00770000120494.
KOiK17635.
OMAiKRGCWSN.
OrthoDBiEOG76DTRS.

Family and domain databases

Gene3Di1.10.840.10. 2 hits.
InterProiIPR000159. Ras-assoc.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
[Graphical view]
SMARTiSM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZS31-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPVRSGPSK LAHWRSLWRT YGNLTGPHWE DDGSQSSPES KAVIRNAIAS
60 70 80 90 100
ILRAWLDQCA EDFREPPHFP CLQKLLEYLK QMMPGSDPER RAQNLLEQFQ
110 120 130 140 150
KQDVDSDNGL LNTISFSPEE EEELESGGSA ELTTFSEDLV AEQLTYMDAQ
160 170 180 190 200
LFKKVVPHHC LGCVWSRRDR KENKHLAPTI RATISQFNAL TKCVVSTILG
210 220 230 240 250
SKDLKTQQRA RVIEKWINIA HECRILKNFS SLRAIVSALQ SNSIYRLKKA
260 270 280 290 300
WAAVPKDRML MFEELSEIFS DHNNHLTSRE LLMKEGTSKF ANLDSSVKEN
310 320 330 340 350
QKRTQRRLQL QKDMGVMQGT VPYLGTFLTD LTMLDTALQD YIEGGLINFE
360 370 380 390 400
KRRREFEVIA QIKLLQSACN SYCMSPDQKF IQWFQRQQLL TEEESYALSC
410 420 430 440 450
EIEAAADAST TSPKPRKSMV KRLSLLFLGS DLIPGSTPTK EQPKSTASGS
460 470 480 490 500
SGESMDSVSV SSCESNHSEA EEGSATPMDT PDEPQKKLSE SSSSCSSIHS
510 520 530 540 550
MDTNSSGMSS LINPLSSPPA CNNNPKMHKR SVSVTSITST VLPPVYNQQN
560 570 580 590 600
EDTCIIRISV EDNNGNMYKS IMLTSQDKTP AVIQRAMSKH NLESDPAEEY
610 620 630 640 650
ELVQVISEDK ELVIPDSANV FYAMNSQVNF DFILRKKSSV EEQVKMRSRT
660 670
SLTMPRTAKR GCWSNRHSKV TL
Length:672
Mass (Da):75,698
Last modified:April 20, 2010 - v1
Checksum:i6680D8BDDB97F90F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06075449 Genomic DNA. No translation available.
AABR06075450 Genomic DNA. No translation available.
AABR06075451 Genomic DNA. No translation available.
AABR06075452 Genomic DNA. No translation available.
AABR06075453 Genomic DNA. No translation available.
AABR06075454 Genomic DNA. No translation available.
AABR06075455 Genomic DNA. No translation available.
AABR06075456 Genomic DNA. No translation available.
AABR06075457 Genomic DNA. No translation available.
CH473958 Genomic DNA. Translation: EDM09558.1.
RefSeqiNP_001099427.1. NM_001105957.1.
UniGeneiRn.28005.

Genome annotation databases

EnsembliENSRNOT00000067135; ENSRNOP00000063014; ENSRNOG00000002347.
GeneIDi289080.
KEGGirno:289080.
UCSCiRGD:1308947. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06075449 Genomic DNA. No translation available.
AABR06075450 Genomic DNA. No translation available.
AABR06075451 Genomic DNA. No translation available.
AABR06075452 Genomic DNA. No translation available.
AABR06075453 Genomic DNA. No translation available.
AABR06075454 Genomic DNA. No translation available.
AABR06075455 Genomic DNA. No translation available.
AABR06075456 Genomic DNA. No translation available.
AABR06075457 Genomic DNA. No translation available.
CH473958 Genomic DNA. Translation: EDM09558.1 .
RefSeqi NP_001099427.1. NM_001105957.1.
UniGenei Rn.28005.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000067135 ; ENSRNOP00000063014 ; ENSRNOG00000002347 .
GeneIDi 289080.
KEGGi rno:289080.
UCSCi RGD:1308947. rat.

Organism-specific databases

CTDi 23179.
RGDi 1308947. Rgl1.

Phylogenomic databases

GeneTreei ENSGT00770000120494.
KOi K17635.
OMAi KRGCWSN.
OrthoDBi EOG76DTRS.

Enzyme and pathway databases

Reactomei REACT_196408. PPARA activates gene expression.

Miscellaneous databases

NextBioi 629181.

Family and domain databases

Gene3Di 1.10.840.10. 2 hits.
InterProi IPR000159. Ras-assoc.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
[Graphical view ]
SMARTi SM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF48366. SSF48366. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZS31_RAT
AccessioniPrimary (citable) accession number: D3ZS31
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3