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D3ZS31

- D3ZS31_RAT

UniProt

D3ZS31 - D3ZS31_RAT

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Protein
Submitted name:

Lethal(2) giant larvae protein homolog 1

Gene
Rgl1, Rgl1_predicted, rCG_46416
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

GO - Biological processi

  1. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factorSAAS annotations

Enzyme and pathway databases

ReactomeiREACT_196408. PPARA activates gene expression.

Names & Taxonomyi

Protein namesi
Submitted name:
Lethal(2) giant larvae protein homolog 1Imported
Submitted name:
Ral guanine nucleotide dissociation stimulator,-like 1 (Predicted), isoform CRA_aImported
Gene namesi
Name:Rgl1Imported
Synonyms:Rgl1_predictedImported
ORF Names:rCG_46416Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 13

Organism-specific databases

RGDi1308947. Rgl1.

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Contains N-terminal Ras-GEF domain.SAAS annotations
Contains Ras-GEF domain.SAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000115163.
KOiK17635.
OMAiKRGCWSN.
OrthoDBiEOG76DTRS.

Family and domain databases

Gene3Di1.10.840.10. 2 hits.
InterProiIPR000159. Ras-assoc.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
[Graphical view]
SMARTiSM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZS31-1 [UniParc]FASTAAdd to Basket

« Hide

MRPVRSGPSK LAHWRSLWRT YGNLTGPHWE DDGSQSSPES KAVIRNAIAS    50
ILRAWLDQCA EDFREPPHFP CLQKLLEYLK QMMPGSDPER RAQNLLEQFQ 100
KQDVDSDNGL LNTISFSPEE EEELESGGSA ELTTFSEDLV AEQLTYMDAQ 150
LFKKVVPHHC LGCVWSRRDR KENKHLAPTI RATISQFNAL TKCVVSTILG 200
SKDLKTQQRA RVIEKWINIA HECRILKNFS SLRAIVSALQ SNSIYRLKKA 250
WAAVPKDRML MFEELSEIFS DHNNHLTSRE LLMKEGTSKF ANLDSSVKEN 300
QKRTQRRLQL QKDMGVMQGT VPYLGTFLTD LTMLDTALQD YIEGGLINFE 350
KRRREFEVIA QIKLLQSACN SYCMSPDQKF IQWFQRQQLL TEEESYALSC 400
EIEAAADAST TSPKPRKSMV KRLSLLFLGS DLIPGSTPTK EQPKSTASGS 450
SGESMDSVSV SSCESNHSEA EEGSATPMDT PDEPQKKLSE SSSSCSSIHS 500
MDTNSSGMSS LINPLSSPPA CNNNPKMHKR SVSVTSITST VLPPVYNQQN 550
EDTCIIRISV EDNNGNMYKS IMLTSQDKTP AVIQRAMSKH NLESDPAEEY 600
ELVQVISEDK ELVIPDSANV FYAMNSQVNF DFILRKKSSV EEQVKMRSRT 650
SLTMPRTAKR GCWSNRHSKV TL 672
Length:672
Mass (Da):75,698
Last modified:April 20, 2010 - v1
Checksum:i6680D8BDDB97F90F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06075449 Genomic DNA. No translation available.
AABR06075450 Genomic DNA. No translation available.
AABR06075451 Genomic DNA. No translation available.
AABR06075452 Genomic DNA. No translation available.
AABR06075453 Genomic DNA. No translation available.
AABR06075454 Genomic DNA. No translation available.
AABR06075455 Genomic DNA. No translation available.
AABR06075456 Genomic DNA. No translation available.
AABR06075457 Genomic DNA. No translation available.
CH473958 Genomic DNA. Translation: EDM09558.1.
RefSeqiNP_001099427.1. NM_001105957.1.
UniGeneiRn.28005.

Genome annotation databases

EnsembliENSRNOT00000067135; ENSRNOP00000063014; ENSRNOG00000002347.
GeneIDi289080.
KEGGirno:289080.
UCSCiRGD:1308947. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06075449 Genomic DNA. No translation available.
AABR06075450 Genomic DNA. No translation available.
AABR06075451 Genomic DNA. No translation available.
AABR06075452 Genomic DNA. No translation available.
AABR06075453 Genomic DNA. No translation available.
AABR06075454 Genomic DNA. No translation available.
AABR06075455 Genomic DNA. No translation available.
AABR06075456 Genomic DNA. No translation available.
AABR06075457 Genomic DNA. No translation available.
CH473958 Genomic DNA. Translation: EDM09558.1 .
RefSeqi NP_001099427.1. NM_001105957.1.
UniGenei Rn.28005.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000067135 ; ENSRNOP00000063014 ; ENSRNOG00000002347 .
GeneIDi 289080.
KEGGi rno:289080.
UCSCi RGD:1308947. rat.

Organism-specific databases

CTDi 23179.
RGDi 1308947. Rgl1.

Phylogenomic databases

GeneTreei ENSGT00740000115163.
KOi K17635.
OMAi KRGCWSN.
OrthoDBi EOG76DTRS.

Enzyme and pathway databases

Reactomei REACT_196408. PPARA activates gene expression.

Miscellaneous databases

NextBioi 629181.

Family and domain databases

Gene3Di 1.10.840.10. 2 hits.
InterProi IPR000159. Ras-assoc.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
[Graphical view ]
SMARTi SM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF48366. SSF48366. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZS31_RAT
AccessioniPrimary (citable) accession number: D3ZS31
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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