Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D3ZRK7

- D3ZRK7_RAT

UniProt

D3ZRK7 - D3ZRK7_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Cell division cycle 6 homolog (S. cerevisiae) (Predicted), isoform CRA_a

Gene

Cdc6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. chromatin binding Source: Ensembl

GO - Biological processi

  1. cell division Source: UniProtKB-KW
  2. positive regulation of chromosome segregation Source: Ensembl
  3. positive regulation of cytokinesis Source: Ensembl
  4. regulation of mitotic metaphase/anaphase transition Source: Ensembl
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell divisionImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_196414. G1/S-Specific Transcription.
REACT_199174. G0 and Early G1.
REACT_204904. Activation of ATR in response to replication stress.
REACT_206997. CDT1 association with the CDC6:ORC:origin complex.
REACT_208829. Assembly of the pre-replicative complex.
REACT_209879. Activation of the pre-replicative complex.
REACT_211117. Orc1 removal from chromatin.
REACT_212486. CDK-mediated phosphorylation and removal of Cdc6.
REACT_212543. Removal of licensing factors from origins.
REACT_213976. CDC6 association with the ORC:origin complex.
REACT_223712. Association of licensing factors with the pre-replicative complex.

Names & Taxonomyi

Protein namesi
Submitted name:
Cell division cycle 6 homolog (S. cerevisiae) (Predicted), isoform CRA_aImported
Submitted name:
Protein Cdc6Imported
Gene namesi
Name:Cdc6Imported
Synonyms:Cdc6_predictedImported
ORF Names:rCG_34910Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 10

Organism-specific databases

RGDi1309157. Cdc6.

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: Ensembl
  2. nucleus Source: Ensembl
  3. spindle midzone Source: Ensembl
  4. spindle pole Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063498.
KOiK02213.
OMAiPYTRNQI.
OrthoDBiEOG7QG44J.
TreeFamiTF101051.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR015163. Cdc6_C_dom.
IPR016314. Cell_div_Cdc6/18.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF09079. Cdc6_C. 1 hit.
[Graphical view]
PIRSFiPIRSF001767. Cdc6. 1 hit.
SMARTiSM00382. AAA. 1 hit.
SM01074. Cdc6_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZRK7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPQTRSQTQA TIDFPKKKQS KTLSKTNSRD SEVKLRNVQP VPTTPCADIK
60 70 80 90 100
ILPLSPRKRL GDDNLCNTPH LSPCSPPKLG RKENGPPRSH TRKGCRLIFD
110 120 130 140 150
DELAVKASAP KEQDRVPQHQ ILSSAQRGQE SETNPEQKCP PEKESACMRL
160 170 180 190 200
FKQEGTCYQQ AKLVLNTAVP DRLPAREQEM GVIRDFLKEH ICGKKAGSLY
210 220 230 240 250
LSGAPGTGKT ACLSRILQDF KKEVKGFKTI VLNCMSLRNA QAVFPAIAQE
260 270 280 290 300
IGREELCRPT GKDLMRKLEK HLTAERGPMI VLVLDEMDQL DSKGQDVLYT
310 320 330 340 350
LFEWPWLSNS RLVLIGIANT LDLTDRILPR LEAREGCKPK LLNFPPYTRN
360 370 380 390 400
QIAAILQDRL SQVSKDQVLD SAAIQFCARK VSAVSGDIRK ALDVCRRAIE
410 420 430 440 450
IVESDVRSQT VLKPLSECKS PCESLVPKRV GLAHISQVIS GVDGNRVTLS
460 470 480 490 500
QENTQDSLPL QQKILVCSLL LLTKRLKIKE VTLGKLYEAY SSVCRKQQVA
510 520 530 540 550
AVDQSECLSL SGLLESRGIV GLKKNKESRL TKVSLKIEEK EIEHVLKGKA
560
FIGNILAAGL P
Length:561
Mass (Da):62,313
Last modified:April 20, 2010 - v1
Checksum:iDB442EA93D249296
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06065511 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM05961.1.
CH473948 Genomic DNA. Translation: EDM05962.1.
RefSeqiNP_001101768.1. NM_001108298.1.
XP_006247416.1. XM_006247354.2.
UniGeneiRn.219688.

Genome annotation databases

EnsembliENSRNOT00000038228; ENSRNOP00000032177; ENSRNOG00000027787.
GeneIDi360621.
KEGGirno:360621.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06065511 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM05961.1 .
CH473948 Genomic DNA. Translation: EDM05962.1 .
RefSeqi NP_001101768.1. NM_001108298.1.
XP_006247416.1. XM_006247354.2.
UniGenei Rn.219688.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000038228 ; ENSRNOP00000032177 ; ENSRNOG00000027787 .
GeneIDi 360621.
KEGGi rno:360621.

Organism-specific databases

CTDi 990.
RGDi 1309157. Cdc6.

Phylogenomic databases

GeneTreei ENSGT00530000063498.
KOi K02213.
OMAi PYTRNQI.
OrthoDBi EOG7QG44J.
TreeFami TF101051.

Enzyme and pathway databases

Reactomei REACT_196414. G1/S-Specific Transcription.
REACT_199174. G0 and Early G1.
REACT_204904. Activation of ATR in response to replication stress.
REACT_206997. CDT1 association with the CDC6:ORC:origin complex.
REACT_208829. Assembly of the pre-replicative complex.
REACT_209879. Activation of the pre-replicative complex.
REACT_211117. Orc1 removal from chromatin.
REACT_212486. CDK-mediated phosphorylation and removal of Cdc6.
REACT_212543. Removal of licensing factors from origins.
REACT_213976. CDC6 association with the ORC:origin complex.
REACT_223712. Association of licensing factors with the pre-replicative complex.

Miscellaneous databases

NextBioi 673491.
PROi D3ZRK7.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR015163. Cdc6_C_dom.
IPR016314. Cell_div_Cdc6/18.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF09079. Cdc6_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF001767. Cdc6. 1 hit.
SMARTi SM00382. AAA. 1 hit.
SM01074. Cdc6_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZRK7_RAT
AccessioniPrimary (citable) accession number: D3ZRK7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3