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Protein
Submitted name:

Growth arrest-specific 2 like 1 (Predicted), isoform CRA_a

Gene

Gas2l1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cytoskeletal adaptor activity Source: UniProtKB
  • microtubule binding Source: UniProtKB
  • thyroid hormone receptor binding Source: UniProtKB

GO - Biological processi

  • cell cycle arrest Source: RGD
  • cellular response to starvation Source: RGD
  • cellular response to thyroid hormone stimulus Source: UniProtKB
  • microtubule bundle formation Source: UniProtKB
  • negative regulation of cell growth Source: UniProtKB
  • negative regulation of erythrocyte differentiation Source: UniProtKB
  • negative regulation of gene expression Source: UniProtKB
  • negative regulation of microtubule depolymerization Source: UniProtKB
  • regulation of cell cycle Source: UniProtKB

Names & Taxonomyi

Protein namesi
Submitted name:
Growth arrest-specific 2 like 1 (Predicted), isoform CRA_aImported
Submitted name:
Growth arrest-specific 2-like 1Imported
Gene namesi
Name:Gas2l1Imported
Synonyms:Gas2l1_predictedImported
ORF Names:rCG_36006Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi1311206 Gas2l1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiD3ZR69

Expressioni

Gene expression databases

BgeeiENSRNOG00000009040

Interactioni

GO - Molecular functioni

  • cytoskeletal adaptor activity Source: UniProtKB
  • microtubule binding Source: UniProtKB
  • thyroid hormone receptor binding Source: UniProtKB

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063743

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 147Calponin-homology (CH)InterPro annotationAdd BLAST121
Domaini203 – 275GARInterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG0516 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00390000002205
OMAiLCSHANH
OrthoDBiEOG091G0PJ6

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
3.30.920.20, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR029931 GAS2L1
PANTHERiPTHR44878 PTHR44878, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
PF02187 GAS2, 1 hit
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00243 GAS2, 1 hit
SUPFAMiSSF143575 SSF143575, 1 hit
SSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS51460 GAR, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZR69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPVAGIAG SAAKSVRPFR SSEAYVEAMK EDLADWLNAL YSLGLPGSGD
60 70 80 90 100
GFLTGLATGT TLCQHANAVT KAARALAAAR PTRGVAFQAH SVAPGSFMAR
110 120 130 140 150
DNVASFIGWC RAELGVPEVL MFETEDLVLR KNEKSVVLCL LEVARRGARL
160 170 180 190 200
GLLAPRLVQF EQEIERELRA TPQASSVPAA EEDVTEIAAA PGAPARTPRM
210 220 230 240 250
TPNDIRNLDE LVREILGKCT CPDQFPMIKV SEGKYRVGDS SLLIFVRVLR
260 270 280 290 300
NHVMVRVGGG WDTLEHYLDK HDPCRCTSST HRLPQQRTGT FSPQRGSPTP
310 320 330 340 350
SPRPGSPVPG SERRSSRPEV TPISLRSTKE GPETPLRSPG FWNHLQVCEL
360 370 380 390 400
LLASRSRREW INSAPSLNLT AGRKAGTCLA ALPLGLCVLL GPAPEFSEVS
410 420
FPSWAFLGVA RSIVGGAPLG PSECLCCF
Length:428
Mass (Da):46,041
Last modified:April 20, 2010 - v1
Checksum:i9384857282BDAC8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07072424 Genomic DNA No translation available.
CH473963 Genomic DNA Translation: EDM00264.1
RefSeqiNP_001101835.1, NM_001108365.1
UniGeneiRn.22169

Genome annotation databases

EnsembliENSRNOT00000065135; ENSRNOP00000063743; ENSRNOG00000009040
GeneIDi360973
KEGGirno:360973
UCSCiRGD:1311206 rat

Similar proteinsi

Entry informationi

Entry nameiD3ZR69_RAT
AccessioniPrimary (citable) accession number: D3ZR69
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 25, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health