Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Growth arrest-specific 2 like 1 (Predicted), isoform CRA_a

Gene

Gas2l1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cytoskeletal adaptor activity Source: UniProtKB
  • microtubule binding Source: UniProtKB
  • thyroid hormone receptor binding Source: UniProtKB

GO - Biological processi

  • cellular response to thyroid hormone stimulus Source: UniProtKB
  • microtubule bundle formation Source: UniProtKB
  • negative regulation of cell growth Source: UniProtKB
  • negative regulation of erythrocyte differentiation Source: UniProtKB
  • negative regulation of gene expression Source: UniProtKB
  • negative regulation of microtubule depolymerization Source: UniProtKB
  • regulation of cell cycle Source: UniProtKB

Names & Taxonomyi

Protein namesi
Submitted name:
Growth arrest-specific 2 like 1 (Predicted), isoform CRA_aImported
Submitted name:
Growth arrest-specific 2-like 1Imported
Gene namesi
Name:Gas2l1Imported
Synonyms:Gas2l1_predictedImported
ORF Names:rCG_36006Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi1311206. Gas2l1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • cytoskeleton Source: UniProtKB-UniRule

Keywords - Cellular componenti

Cytoplasm, CytoskeletonPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000009040.

Interactioni

GO - Molecular functioni

  • cytoskeletal adaptor activity Source: UniProtKB
  • microtubule binding Source: UniProtKB
  • thyroid hormone receptor binding Source: UniProtKB

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063743.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 147Actin-bindingInterPro annotationAdd BLAST121
Domaini203 – 275GARInterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG0516. Eukaryota.
COG5069. LUCA.
GeneTreeiENSGT00390000002205.
OMAiLCSHANH.
OrthoDBiEOG091G0PJ6.

Family and domain databases

CDDicd00014. CH. 1 hit.
Gene3Di1.10.418.10. 1 hit.
3.30.920.20. 1 hit.
InterProiView protein in InterPro
IPR001715. CH-domain.
IPR029931. GAS2L1.
IPR003108. GAS_dom.
PANTHERiPTHR11915:SF370. PTHR11915:SF370. 1 hit.
PfamiView protein in Pfam
PF00307. CH. 1 hit.
PF02187. GAS2. 1 hit.
SMARTiView protein in SMART
SM00033. CH. 1 hit.
SM00243. GAS2. 1 hit.
SUPFAMiSSF143575. SSF143575. 1 hit.
SSF47576. SSF47576. 1 hit.
PROSITEiView protein in PROSITE
PS50021. CH. 1 hit.
PS51460. GAR. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZR69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPVAGIAG SAAKSVRPFR SSEAYVEAMK EDLADWLNAL YSLGLPGSGD
60 70 80 90 100
GFLTGLATGT TLCQHANAVT KAARALAAAR PTRGVAFQAH SVAPGSFMAR
110 120 130 140 150
DNVASFIGWC RAELGVPEVL MFETEDLVLR KNEKSVVLCL LEVARRGARL
160 170 180 190 200
GLLAPRLVQF EQEIERELRA TPQASSVPAA EEDVTEIAAA PGAPARTPRM
210 220 230 240 250
TPNDIRNLDE LVREILGKCT CPDQFPMIKV SEGKYRVGDS SLLIFVRVLR
260 270 280 290 300
NHVMVRVGGG WDTLEHYLDK HDPCRCTSST HRLPQQRTGT FSPQRGSPTP
310 320 330 340 350
SPRPGSPVPG SERRSSRPEV TPISLRSTKE GPETPLRSPG FWNHLQVCEL
360 370 380 390 400
LLASRSRREW INSAPSLNLT AGRKAGTCLA ALPLGLCVLL GPAPEFSEVS
410 420
FPSWAFLGVA RSIVGGAPLG PSECLCCF
Length:428
Mass (Da):46,041
Last modified:April 20, 2010 - v1
Checksum:i9384857282BDAC8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07072424 Genomic DNA. No translation available.
CH473963 Genomic DNA. Translation: EDM00264.1.
RefSeqiNP_001101835.1. NM_001108365.1.
UniGeneiRn.22169.

Genome annotation databases

EnsembliENSRNOT00000065135; ENSRNOP00000063743; ENSRNOG00000009040.
GeneIDi360973.
KEGGirno:360973.
UCSCiRGD:1311206. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD3ZR69_RAT
AccessioniPrimary (citable) accession number: D3ZR69
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 5, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported