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D3ZQD3

- D3ZQD3_RAT

UniProt

D3ZQD3 - D3ZQD3_RAT

Protein
Submitted name:

2-oxoglutarate dehydrogenase, mitochondrial

Gene

Ogdhl

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
    2. thiamine pyrophosphate binding Source: InterPro

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-oxoglutarate dehydrogenase, mitochondrialImported
    Submitted name:
    Oxoglutarate dehydrogenase-like (Predicted), isoform CRA_aImported
    Gene namesi
    Name:OgdhlImported
    Synonyms:Ogdhl_predictedImported
    ORF Names:rCG_42296Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 16

    Organism-specific databases

    RGDi1310916. Ogdhl.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000063092.
    KOiK00164.
    OMAiDMTRKRT.
    OrthoDBiEOG7FXZXH.
    TreeFamiTF300695.

    Family and domain databases

    Gene3Di3.40.50.970. 2 hits.
    InterProiIPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view]
    PANTHERiPTHR23152. PTHR23152. 1 hit.
    PfamiPF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 2 hits.
    TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D3ZQD3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQLRLLLFR LGPQARKLLA TRDIAAFGGR RRSSGPPTTI PRSRGGVSPS     50
    YVEEMYFAWL ENPQSVHKSW DNFFQRATKE ASVGPAQPQP PAVIQESRAS 100
    VSSCTKTSKL VEDHLAVQSL IRAYQIRGHH VAQLDPLGIL DADLDSFVPS 150
    DLITTIDKLA FYDLQEADLD KEFRLPTTTF IGGSENTLSL REIIRRLEST 200
    YCQHIGLEFM FINDVEQCQW IRQKFETPGV MKFSIEEKRT LLARLVRSMR 250
    FEDFLARKWS SEKRFGLEGC EVMIPALKTI IDKSSEMGVE NVILGMPHRG 300
    RLNVLANVIR KDLEQIFCQF DPKLEAADEG SGDVKYHLGM YHERINRVTN 350
    RNITLSLVAN PSHLEAVDPV VQGKTKAEQF YRGDAQGRKV MSILVHGDAA 400
    FAGQGVVYET FHLSDLPSYT TNGTVHVVVN NQIGFTTDPR MARSSPYPTD 450
    VARVVNAPIF HVNADDPEAV IYVCSVAAEW RNTFNKDVVV DLVCYRRRGH 500
    NEMDEPMFTQ PLMYKQIHKQ VPVLKKYADK LIAEGTVTLQ EFEEEIAKYD 550
    RICEEAYGRS KDKKILHIKH WLDSPWPGFF NVDGEPKSMT YPTTGIPEDT 600
    LSHIGNVASS VPLEDFKIHT GLSRILRGRA DMTKKRTVDW ALAEYMAFGS 650
    LLKEGIHVRL SGQDVERGTF SHRHHVLHDQ DVDRRTCVPM NHLWPDQAPY 700
    TVCNSSLSEY GVLGFELGYA MASPNALVLW EAQFGDFHNT AQCIIDQFIS 750
    TGQAKWVRHN GIVLLLPHGM EGMGPEHSSA RPERFLQMSN DDSDAYPVFT 800
    EDFEVSQLYD CNWIVVNCST PASYFHVLRR QVLLPFRKPG WMWGPIDGAP 850
    GGWLFAFQLI VFTPKSLLRH PDAKSSFDQM VSGTSFQRMI PEDGPAAQSP 900
    ERVERLIFCT GKVYYDLVKE RSSQGLEKQV AITRLEQISP FPFDLIMREA 950
    EKYSGAELVW CQEEHKNMGY YDYISPRFMT LLGHSRPIWY VGREPAAAPA 1000
    TGNKNTHLVS LRKFLDTAFN LKAFEGKTF 1029
    Length:1,029
    Mass (Da):116,712
    Last modified:April 20, 2010 - v1
    Checksum:iD2E3505CEA4F4EB1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06086413 Genomic DNA. No translation available.
    CH474046 Genomic DNA. Translation: EDL88917.1.
    CH474046 Genomic DNA. Translation: EDL88918.1.
    RefSeqiNP_001099532.1. NM_001106062.1.
    UniGeneiRn.38202.

    Genome annotation databases

    EnsembliENSRNOT00000027054; ENSRNOP00000027054; ENSRNOG00000019955.
    GeneIDi290566.
    KEGGirno:290566.
    UCSCiRGD:1310916. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06086413 Genomic DNA. No translation available.
    CH474046 Genomic DNA. Translation: EDL88917.1 .
    CH474046 Genomic DNA. Translation: EDL88918.1 .
    RefSeqi NP_001099532.1. NM_001106062.1.
    UniGenei Rn.38202.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000027054 ; ENSRNOP00000027054 ; ENSRNOG00000019955 .
    GeneIDi 290566.
    KEGGi rno:290566.
    UCSCi RGD:1310916. rat.

    Organism-specific databases

    CTDi 55753.
    RGDi 1310916. Ogdhl.

    Phylogenomic databases

    GeneTreei ENSGT00530000063092.
    KOi K00164.
    OMAi DMTRKRT.
    OrthoDBi EOG7FXZXH.
    TreeFami TF300695.

    Miscellaneous databases

    NextBioi 631224.

    Family and domain databases

    Gene3Di 3.40.50.970. 2 hits.
    InterProi IPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view ]
    PANTHERi PTHR23152. PTHR23152. 1 hit.
    Pfami PF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 2 hits.
    TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD3ZQD3_RAT
    AccessioniPrimary (citable) accession number: D3ZQD3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3