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Protein
Submitted name:

P21 (RAC1)-activated kinase 6

Gene

Pak6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
P21 (RAC1)-activated kinase 6Imported
Submitted name:
p21 (CDKN1A)-activated kinase 6 (Predicted)Imported
Gene namesi
Name:Pak6Imported
Synonyms:Pak6_predictedImported
ORF Names:rCG_26141Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1306213. Pak6.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSRNOG00000007925.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010471.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 25CRIBInterPro annotationAdd BLAST14
Domaini407 – 658Protein kinaseInterPro annotationAdd BLAST252

Phylogenomic databases

eggNOGiKOG0578. Eukaryota.
ENOG410XP4K. LUCA.
GeneTreeiENSGT00860000133680.
KOiK05735.
OMAiEARPQSC.
TreeFamiTF105352.

Family and domain databases

CDDicd01093. CRIB_PAK_like. 1 hit.
Gene3Di3.90.810.10. 1 hit.
InterProiView protein in InterPro
IPR000095. CRIB_dom.
IPR011009. Kinase-like_dom.
IPR035066. PAK6.
IPR033923. PAK_BD.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
PANTHERiPTHR24361:SF525. PTHR24361:SF525. 1 hit.
PfamiView protein in Pfam
PF00786. PBD. 1 hit.
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00285. PBD. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50108. CRIB. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZQ51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRKKKKKRP EISAPQNFQH RVHTSFDPKE GKFVGLPPQW QNILDTLRRP
60 70 80 90 100
KPVVDPSRIT RVQLQPMKTV VRGSSVPTEG YISGLLNDIQ KLSAISSNTL
110 120 130 140 150
RGRSPTSRRR AQSLGLLGDD QWAADPDMYL QSPQSERTDP HGVYLSCNGG
160 170 180 190 200
TPAGHRQTPW PEPQSPQALP NGMAAKAQSL GPAEFQGASQ RCLQLGACLQ
210 220 230 240 250
SSPPGTSPPM ATGRRGVKVT KHSSEEARPQ SCLVGSAIGR PGGEGSPSPK
260 270 280 290 300
TQESSLKHRL FRSMFLSTPA TGSASSSKPV PLPQNKLNSA FRPPQKDSSS
310 320 330 340 350
NLVAKAQSLP SDQPTGTFSP LTTSDTSSPQ KSLRTAPATG PLPGRSSPAG
360 370 380 390 400
SPRTRHAQIS TSNLYLPQDP TVAKGALGGE DTGIVTHEQF KAALRMVVDQ
410 420 430 440 450
GDPRLLLDSY VKIGEGSTGI VCLAREKHSG RQVAVKMMDL RKQQRRELLF
460 470 480 490 500
NEVVIMRDYQ HLNVVEMYKS YLVGEELWVL MEFLQGGALT DIISQVRLNE
510 520 530 540 550
EQIATVCEAV LQALAYLHAQ GVIHRDIKSD SILLTLDGRV KLSDFGFCAQ
560 570 580 590 600
ISKDVPKRKS LVGTPYWMAP EVISRSLYAT EVDIWSLGIM VIEMVDGEPP
610 620 630 640 650
YFSDSPVQAM KRLRDSPPPK LKNSYKVSPV LRDFLERMLV REPQERATAQ
660 670 680
ELLDHPFLLQ TGLPECLVPL IQLYRKQTST C
Length:681
Mass (Da):74,793
Last modified:April 3, 2013 - v2
Checksum:i682637B4A4717091
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07053496 Genomic DNA. No translation available.
AABR07053497 Genomic DNA. No translation available.
AABR07053498 Genomic DNA. No translation available.
AABR07053499 Genomic DNA. No translation available.
CH473949 Genomic DNA. Translation: EDL79867.1.
RefSeqiNP_001099968.1. NM_001106498.1.
XP_017447064.1. XM_017591575.1.
UniGeneiRn.218297.

Genome annotation databases

EnsembliENSRNOT00000010471; ENSRNOP00000010471; ENSRNOG00000007925.
ENSRNOT00000089434; ENSRNOP00000075254; ENSRNOG00000007925.
GeneIDi296078.
KEGGirno:296078.
UCSCiRGD:1306213. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD3ZQ51_RAT
AccessioniPrimary (citable) accession number: D3ZQ51
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: July 5, 2017
This is version 64 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported