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Protein
Submitted name:

Adhesion G protein-coupled receptor L2

Gene

Adgrl2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor L2Imported
Gene namesi
Name:Adgrl2Imported
Synonyms:Lphn2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi620835 Adgrl2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei849 – 876HelicalSequence analysisAdd BLAST28
Transmembranei888 – 905HelicalSequence analysisAdd BLAST18
Transmembranei917 – 944HelicalSequence analysisAdd BLAST28
Transmembranei956 – 975HelicalSequence analysisAdd BLAST20
Transmembranei995 – 1018HelicalSequence analysisAdd BLAST24
Transmembranei1039 – 1062HelicalSequence analysisAdd BLAST24
Transmembranei1068 – 1091HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500841330826 – 1420Sequence analysisAdd BLAST1395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi140 ↔ 322PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PeptideAtlasiD3ZNG0

Expressioni

Gene expression databases

BgeeiENSRNOG00000032660
ExpressionAtlasiD3ZNG0 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 130SUEL-type lectinInterPro annotationAdd BLAST90
Domaini139 – 398Olfactomedin-likeInterPro annotationAdd BLAST260
Domaini472 – 529G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST58
Domaini789 – 840GPSInterPro annotationAdd BLAST52
Domaini851 – 1092G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3545 Eukaryota
KOG4193 Eukaryota
KOG4729 Eukaryota
ENOG410XSD2 LUCA
GeneTreeiENSGT00900000140800

Family and domain databases

Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR032471 GAIN_dom_N
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR003924 GPCR_2_latrophilin
IPR003334 GPCR_2_latrophilin_rcpt_C
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR031240 Latrophilin-2
IPR000922 Lectin_gal-bd_dom
IPR003112 Olfac-like_dom
PANTHERiPTHR12011:SF61 PTHR12011:SF61, 1 hit
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF16489 GAIN, 1 hit
PF02140 Gal_Lectin, 1 hit
PF01825 GPS, 1 hit
PF02793 HRM, 1 hit
PF02354 Latrophilin, 2 hits
PF02191 OLF, 1 hit
PRINTSiPR00249 GPCRSECRETIN
PR01444 LATROPHILIN
SMARTiView protein in SMART
SM00303 GPS, 1 hit
SM00008 HormR, 1 hit
SM00284 OLF, 1 hit
PROSITEiView protein in PROSITE
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51132 OLF, 1 hit
PS50228 SUEL_LECTIN, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZNG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSSGCRMRS LWFIMIISFS PNTEGFSRAA LPFGLVRREL SCEGYSIDLR
60 70 80 90 100
CPGSDVIMIE SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR
110 120 130 140 150
TQCVVVTGSD VFPDPCPGTY KYLEVQYECV PYMEQKVFVC PGTLKAIVDS
160 170 180 190 200
PSIYEAEQKA GAWCKDPLQA ADKIYFMPWT PYRTDTLIEY ASLEDFQNSR
210 220 230 240 250
QTTTYKLPNR VDGTGFVVYD GAVFFNKERT RNIVKFDLRT RIKSGEAIIN
260 270 280 290 300
YANYHDTSPY RWGGKTDIDL AVDENGLWVI YATEQNNGMI VISQLNPYTL
310 320 330 340 350
RFEATWETTY DKRAASNAFM ICGVLYVVRS VYQDNESEAG KNVIDYIYNT
360 370 380 390 400
RLSRGEHVDV PFPNQYQYIA AVDYNPRDNQ LYVWNNNFIL RYSLEFGPPD
410 420 430 440 450
PAQVPTTAVT ITSSAELFKT TVSTTSSTSQ RGPVSSTVAG PQEGSRGTKP
460 470 480 490 500
PPAVSTTKIP PVTNIFPLPE RFCEALEMKG IKWPQTQRGM MVERPCPKGT
510 520 530 540 550
RGTASYLCMA STGTWNPKGP DLSNCTSHWV NQLAQKIRSG ENAASLANEL
560 570 580 590 600
AKHTKGTVFA GDVSSSVRLM EQLVDILDAQ LQELKPSEKD SAGRSYNKLQ
610 620 630 640 650
KREKTCRAYL KAIVDTVDNL LRAETLDCWK HMNSSEQAHT ATMLLDTLEE
660 670 680 690 700
GAFVLADNLL EPTRVSMPTD NIVLEVAVLS TEGQVQDFTF HLGFKGAFSS
710 720 730 740 750
IQLSANTVKQ NSRNGLAKVV FIIYRSLGPF LSTENATVKL GADLLGRNST
760 770 780 790 800
IAVNSHVLSV SINKESSRVY LTDPVLFSMP HIDSDNYFNA NCSFWNYSER
810 820 830 840 850
TMMGYWSTQG CKLVDTNKTR TTCACSHLTN FAILMAHREI VYKDGVHKLL
860 870 880 890 900
LTVITWVGIV VSLVCLAICI FTFCFFRGLQ SDRNTIHKNL CINLFIAEFI
910 920 930 940 950
FLIGIDKTQY TIACPVFAGL LHFFFLAAFS WMCLEGVQLY LMLVEVFESE
960 970 980 990 1000
YSRKKYYYVA GYLFPATVVG VSAAIDYKSY GTLEACWLHV DNYFIWSFIG
1010 1020 1030 1040 1050
PVTFIILLNI IFLVITLCKM VKHSNTLKPD SSRLENIKSW VLGAFALLCL
1060 1070 1080 1090 1100
LGLTWSFGLL FVNEETVVMA YLFTAFNAFQ GLFIFIFHCA LQKKVRKEYA
1110 1120 1130 1140 1150
KCFRHWYCCG GLPTESPHSS VKASTSRTSA RYSSGTQSRI RRMWNDTVRK
1160 1170 1180 1190 1200
QSESSFISGD INSTSTLNQG HSLNNTRDTS AMDTLPLNGN FNNSYSLRKA
1210 1220 1230 1240 1250
DYHDGVQVVD CGLSLNDTAF EKMIISELVH NNLRGSNKTH NLELKLPVKP
1260 1270 1280 1290 1300
VIGGSSSEDD AIVADASSLM HGDNPGLEFR HKELEAPLIP QRTHSLLYQP
1310 1320 1330 1340 1350
QKKVKPEATD SYVSQLTAEA DEHLQSPNRD SLYTSMPNLR DSPYPESSPD
1360 1370 1380 1390 1400
MAEDLSPSRR SENEDIYYKS MPNLGAGRQL QMCYQISRGN SDGYIIPINK
1410 1420
EGCIPEGDVR EGQMQLVTSL
Length:1,420
Mass (Da):159,399
Last modified:October 5, 2016 - v4
Checksum:iBD8E306F7290515E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07013841 Genomic DNA No translation available.
AABR07013842 Genomic DNA No translation available.
RefSeqiNP_001289141.1, NM_001302212.1
UniGeneiRn.12089

Genome annotation databases

EnsembliENSRNOT00000045020; ENSRNOP00000041829; ENSRNOG00000032660
GeneIDi171447

Similar proteinsi

Entry informationi

Entry nameiD3ZNG0_RAT
AccessioniPrimary (citable) accession number: D3ZNG0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 68 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health