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Protein
Submitted name:

Adhesion G protein-coupled receptor L2

Gene

Adgrl2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor L2Imported
Gene namesi
Name:Adgrl2Imported
Synonyms:Lphn2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi620835. Adgrl2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

ExpressionAtlasiD3ZNG0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000042136.

Structurei

3D structure databases

ProteinModelPortaliD3ZNG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SUEL-type lectin domain.UniRule annotation
Contains GPS domain.SAAS annotation
Contains olfactomedin-like domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Family and domain databases

InterProiIPR022624. DUF3497.
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003924. GPCR_2_latrophilin.
IPR003334. GPCR_2_latrophilin_rcpt_C.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR031240. Latrophilin-2.
IPR000922. Lectin_gal-bd_dom.
IPR003112. Olfac-like.
[Graphical view]
PANTHERiPTHR12011:SF61. PTHR12011:SF61. 1 hit.
PfamiPF00002. 7tm_2. 1 hit.
PF12003. DUF3497. 1 hit.
PF02140. Gal_Lectin. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF02354. Latrophilin. 2 hits.
PF02191. OLF. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
PR01444. LATROPHILIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00284. OLF. 1 hit.
[Graphical view]
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS51132. OLF. 1 hit.
PS50228. SUEL_LECTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZNG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GFSRAALPFG LVRRELSCEG YSIDLRCPGS DVIMIESANY GRTDDKICDA
60 70 80 90 100
DPFQMENTDC YLPDAFKIMT QRCNNRTQCV VVTGSDVFPD PCPGTYKYLE
110 120 130 140 150
VQYECVPYME QKVFVCPGTL KAIVDSPSIY EAEQKAGAWC KDPLQAADKI
160 170 180 190 200
YFMPWTPYRT DTLIEYASLE DFQNSRQTTT YKLPNRVDGT GFVVYDGAVF
210 220 230 240 250
FNKERTRNIV KFDLRTRIKS GEAIINYANY HDTSPYRWGG KTDIDLAVDE
260 270 280 290 300
NGLWVIYATE QNNGMIVISQ LNPYTLRFEA TWETTYDKRA ASNAFMICGV
310 320 330 340 350
LYVVRSVYQD NESEAGKNVI DYIYNTRLSR GEHVDVPFPN QYQYIAAVDY
360 370 380 390 400
NPRDNQLYVW NNNFILRYSL EFGPPDPAQV PTTAVTITSS AELFKTTVST
410 420 430 440 450
TSSTSQRGPV SSTVAGPQEG SRGTKPPPAV STTKIPPVTN IFPLPERFCE
460 470 480 490 500
ALEMKGIKWP QTQRGMMVER PCPKGTRGTA SYLCMASTGT WNPKGPDLSN
510 520 530 540 550
CTSHWVNQLA QKIRSGENAA SLANELAKHT KGTVFAGDVS SSVRLMEQLV
560 570 580 590 600
DILDAQLQEL KPSEKDSAGR SYNKLQKREK TCRAYLKAIV DTVDNLLRAE
610 620 630 640 650
TLDCWKHMNS SEQAHTATML LDTLEEGAFV LADNLLEPTR VSMPTDNIVL
660 670 680 690 700
EVAVLSTEGQ VQDFTFHLGF KGAFSSIQLS ANTVKQNSRN GLAKVVFIIY
710 720 730 740 750
RSLGPFLSTE NATVKLGADL LGRNSTIAVN SHVLSVSINK ESSRVYLTDP
760 770 780 790 800
VLFSMPHIDS DNYFNANCSF WNYSERTMMG YWSTQGCKLV DTNKTRTTCA
810 820 830 840 850
CSHLTNFAIL MAHREIVYKD GVHKLLLTVI TWVGIVVSLV CLAICIFTFC
860 870 880 890 900
FFRGLQSDRN TIHKNLCINL FIAEFIFLIG IDKTQYTIAC PVFAGLLHFF
910 920 930 940 950
FLAAFSWMCL EGVQLYLMLV EVFESEYSRK KYYYVAGYLF PATVVGVSAA
960 970 980 990 1000
IDYKSYGTLE ACWLHVDNYF IWSFIGPVTF IILLNIIFLV ITLCKMVKHS
1010 1020 1030 1040 1050
NTLKPDSSRL ENINNYRVCD GYYNTDLPGS WVLGAFALLC LLGLTWSFGL
1060 1070 1080 1090 1100
LFVNEETVVM AYLFTAFNAF QGLFIFIFHC ALQKKVRKEY AKCFRHWYCC
1110 1120 1130 1140 1150
GGLPTESPHS SVKASTSRTS ARYSSGTQSR IRRMWNDTVR KQSESSFISG
1160 1170 1180 1190 1200
DINSTSTLNQ GHSLNNTRDT SAMDTLPLNG NFNNSYSLRK ADYHDGVQVV
1210 1220 1230 1240 1250
DCGLSLNDTA FEKMIISELV HNNLRGSNKT HNLELKLPVK PVIGGSSSED
1260 1270 1280 1290 1300
DAIVADASSL MHGDNPGLEF RHKELEAPLI PQRTHSLLYQ PQKKVKPEAT
1310 1320 1330 1340 1350
DSYVSQLTAE ADEHLQSPNR DSLYTSMPNL RDSPYPESSP DMAEDLSPSR
1360 1370 1380 1390 1400
RSENEDIYYK SMPNLGAGRQ LQMCYQISRG NSDGYIIPIN KEGCIPEGDV
1410
REGQMQLVTS L
Length:1,411
Mass (Da):158,342
Last modified:July 22, 2015 - v3
Checksum:i8570487522885DB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07013841 Genomic DNA. No translation available.
AABR07013842 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000045020; ENSRNOP00000041829; ENSRNOG00000032660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07013841 Genomic DNA. No translation available.
AABR07013842 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3ZNG0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000042136.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000045020; ENSRNOP00000041829; ENSRNOG00000032660.

Organism-specific databases

RGDi620835. Adgrl2.

Miscellaneous databases

NextBioi35568928.

Gene expression databases

ExpressionAtlasiD3ZNG0. baseline and differential.

Family and domain databases

InterProiIPR022624. DUF3497.
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003924. GPCR_2_latrophilin.
IPR003334. GPCR_2_latrophilin_rcpt_C.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR031240. Latrophilin-2.
IPR000922. Lectin_gal-bd_dom.
IPR003112. Olfac-like.
[Graphical view]
PANTHERiPTHR12011:SF61. PTHR12011:SF61. 1 hit.
PfamiPF00002. 7tm_2. 1 hit.
PF12003. DUF3497. 1 hit.
PF02140. Gal_Lectin. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF02354. Latrophilin. 2 hits.
PF02191. OLF. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
PR01444. LATROPHILIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00284. OLF. 1 hit.
[Graphical view]
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS51132. OLF. 1 hit.
PS50228. SUEL_LECTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.
  3. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiD3ZNG0_RAT
AccessioniPrimary (citable) accession number: D3ZNG0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: July 22, 2015
This is version 43 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.