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Protein

Gamma-tubulin complex component

Gene

Tubgcp3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.UniRule annotation

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-380270. Recruitment of mitotic centrosome proteins and complexes.
R-RNO-380320. Recruitment of NuMA to mitotic centrosomes.

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-tubulin complex componentUniRule annotation
Gene namesi
Name:Tubgcp3Imported
ORF Names:rCG_43222Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1305726. Tubgcp3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060338.

Family & Domainsi

Sequence similaritiesi

Belongs to the TUBGCP family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2000. Eukaryota.
ENOG410XQ5B. LUCA.
GeneTreeiENSGT00840000129807.
KOiK16570.
OMAiLAWTINT.
OrthoDBiEOG7FFMR6.

Family and domain databases

InterProiIPR007259. GCP.
[Graphical view]
PANTHERiPTHR19302. PTHR19302. 2 hits.
PfamiPF04130. Spc97_Spc98. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZMR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPDQKSPN VLLQNLCCRI LGRSEADVAQ QFQFAVRVIG SNFAPTVERD
60 70 80 90 100
EFLVAEKIKK ELIRQRREAD AALFSELHRK LHSQGVLKNK WSILYLLLNL
110 120 130 140 150
SEDPRKQASK VTSYASLFAQ ALPRDAHSTP YYCARPQTLP LNYQDRSTQS
160 170 180 190 200
SGSLGSSGIS SIGMCGLSGP TPVQPFLPGQ SHQAPGVGDG LRQQLGPRLA
210 220 230 240 250
WTLTGNQPSQ TPTSKAFPNA LSRNLTRSRR EGDPGGTSEV TEAALVRDIL
260 270 280 290 300
YVFQGIDGKN IKMSSTENCY KVEAKANLSK SLRDTAVRLA ELGWLHNKIR
310 320 330 340 350
KYADQRSLDR SFGLVGQSFC AALHQELKEY YRLLSVLHSQ LQLEDDQGVN
360 370 380 390 400
VGLESSLTLR RLLVWTYDPK IRLKTLAALV DHCQGRKGGE LASAVHAYTK
410 420 430 440 450
TGDPYMKSLV QHILSLVSHP VLSFLYRWIY DGELEDTYHE FFVASDPTVK
460 470 480 490 500
TDRLWHDKYT LRKSMIPSFI TMDQSRKVLL IGKSINFLHQ VCHDQTPTTK
510 520 530 540 550
MIAVTKSAES PRDAADLFTD LENAFQGKID AAYFETSKYL LDVLNRKYSL
560 570 580 590 600
LEHMQAMRRY LLLGQGDFIR HLMDLLKSLL VTLGGMSSAW ITTSTDQLPL

CSHESA
Length:606
Mass (Da):67,899
Last modified:April 20, 2010 - v1
Checksum:iCD977E49B68C237A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127756 Genomic DNA. No translation available.
CH473970 Genomic DNA. Translation: EDM08853.1.
RefSeqiNP_001100793.1. NM_001107323.1.
UniGeneiRn.99777.

Genome annotation databases

EnsembliENSRNOT00000068416; ENSRNOP00000060338; ENSRNOG00000017085.
GeneIDi306599.
KEGGirno:306599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127756 Genomic DNA. No translation available.
CH473970 Genomic DNA. Translation: EDM08853.1.
RefSeqiNP_001100793.1. NM_001107323.1.
UniGeneiRn.99777.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060338.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000068416; ENSRNOP00000060338; ENSRNOG00000017085.
GeneIDi306599.
KEGGirno:306599.

Organism-specific databases

CTDi10426.
RGDi1305726. Tubgcp3.

Phylogenomic databases

eggNOGiKOG2000. Eukaryota.
ENOG410XQ5B. LUCA.
GeneTreeiENSGT00840000129807.
KOiK16570.
OMAiLAWTINT.
OrthoDBiEOG7FFMR6.

Enzyme and pathway databases

ReactomeiR-RNO-380270. Recruitment of mitotic centrosome proteins and complexes.
R-RNO-380320. Recruitment of NuMA to mitotic centrosomes.

Miscellaneous databases

NextBioi656287.

Family and domain databases

InterProiIPR007259. GCP.
[Graphical view]
PANTHERiPTHR19302. PTHR19302. 2 hits.
PfamiPF04130. Spc97_Spc98. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZMR7_RAT
AccessioniPrimary (citable) accession number: D3ZMR7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 11, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.