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Protein
Submitted name:

Interleukin 25

Gene

Il25

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • eosinophil differentiation Source: RGD
  • inflammatory response Source: RGD
  • inflammatory response to antigenic stimulus Source: RGD
  • interleukin-13 production Source: RGD
  • interleukin-5 production Source: RGD
  • positive regulation of transcription by RNA polymerase II Source: RGD
  • response to fungus Source: RGD
  • response to nematode Source: RGD

Enzyme and pathway databases

ReactomeiR-RNO-448424 Interleukin-17 signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 25Imported
Gene namesi
Name:Il25Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1561632 Il25

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500305354717 – 169Sequence analysisAdd BLAST153

Proteomic databases

PaxDbiD3ZLB1

PTM databases

iPTMnetiD3ZLB1
PhosphoSitePlusiD3ZLB1

Expressioni

Gene expression databases

BgeeiENSRNOG00000016804

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022563

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IHJ5 Eukaryota
ENOG4111VTD LUCA
GeneTreeiENSGT00690000102299
InParanoidiD3ZLB1
KOiK05493
OMAiFYRRPCP
OrthoDBiEOG091G17O0
PhylomeDBiD3ZLB1
TreeFamiTF314701

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR010345 IL-17_fam
PfamiView protein in Pfam
PF06083 IL17, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZLB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYQAVAFLAM VVGTHTVSLR IQEDCSHLPR CCPSKQQEFP EEWLKWNPAP
60 70 80 90 100
VSPPEPLRHT HHPESCRASK DGPLNSRAIS PWSYELDRDL NRVPQDLYHA
110 120 130 140 150
RCLCPHCVSL QTGSHMDPMG NSVPLYHNQT VFYRRPCHGE QGAHGRYCLE
160
RRLYRVSLAC VCVRPRMMA
Length:169
Mass (Da):19,434
Last modified:April 20, 2010 - v1
Checksum:iE68ED66DF47B12A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115371 Genomic DNA No translation available.
RefSeqiNP_001178936.1, NM_001192007.1
UniGeneiRn.228187

Genome annotation databases

EnsembliENSRNOT00000022563; ENSRNOP00000022563; ENSRNOG00000016804
GeneIDi501996
KEGGirno:501996
UCSCiRGD:1561632 rat

Similar proteinsi

Entry informationi

Entry nameiD3ZLB1_RAT
AccessioniPrimary (citable) accession number: D3ZLB1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: March 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health