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Protein
Submitted name:

ATP-binding cassette, sub-family D (ALD), member 1 (Predicted)

Gene

Abcd1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationImported, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-1369062. ABC transporters in lipid homeostasis.
R-RNO-2046105. Linoleic acid (LA) metabolism.
R-RNO-2046106. alpha-linolenic acid (ALA) metabolism.
R-RNO-390247. Beta-oxidation of very long chain fatty acids.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette, sub-family D (ALD), member 1 (Predicted)Imported
Submitted name:
Protein Abcd1Imported
Gene namesi
Name:Abcd1Imported
Synonyms:Abcd1_predictedImported
ORF Names:rCG_43826Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1562128. Abcd1.

Subcellular locationi

GO - Cellular componenti

  • integral component of peroxisomal membrane Source: Ensembl
  • mitochondrion Source: Ensembl
  • perinuclear region of cytoplasm Source: Ensembl
  • peroxisomal membrane Source: RGD
  • peroxisome Source: UniProtKB
Complete GO annotation...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini100 – 336237ABC transmembrane type-1InterPro annotationAdd
BLAST
Domaini475 – 730256ABC transporterInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG0064. Eukaryota.
COG4178. LUCA.
GeneTreeiENSGT00390000003950.
KOiK05675.
OMAiPRVLCRE.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR031237. ALDP.
IPR005283. FA_transporter.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11384:SF21. PTHR11384:SF21. 1 hit.
PfamiPF06472. ABC_membrane_2. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00954. 3a01203. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZHR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVLSTPSRP SRVTTLKRTA VVLALTAYGV HKIYPLVRQC LTPARGPQVP
60 70 80 90 100
AGESTQEASG ATTAKAGMNR VFLQRLLVLL RLLFPGVLCR ETGLLALHSA
110 120 130 140 150
ALVSRTFLSV YVARLDGRLA RCIVRKDPRA FSWQLLQWLL IALPATFINS
160 170 180 190 200
AIRYLEGQLA LSFRSRLVAH AYGLYFSQQT YYRVSNMDGR LRNPDQSLTE
210 220 230 240 250
DMVAFAASVA HLYSNLTKPL LDVAVTSYTL LRAARSRGAG TAWPSAIAGL
260 270 280 290 300
VVFLTANVLR AFSPKFGELV AEEARRKGEL RYMHSRVVAN SEEIAFYGGH
310 320 330 340 350
EVELALLQHS YQDLASQINL ILLERLWYVM LEQFLMKYVW SASGLLMVAV
360 370 380 390 400
PIITATGYAE SDSEAMKKAA LEMKEEELVS ERTEAFTIAR NLLTAAADAT
410 420 430 440 450
ERIMSSYKEV TELAGYTARV YEMFQVFEDV QHCRFKRTGD LEEAQAGPGS
460 470 480 490 500
MVHSGVHIEG PLKIQGQVVD VEQGIICENI PIITPTGEVV VASLNIRVEE
510 520 530 540 550
GMHLLITGPN GCGKSSLFRI LGGLWPTYSG VLYKPPPQRM FYIPQRPYMS
560 570 580 590 600
VGSLRDQVIY PDSAEDMRRK GCSEQQLEAI LGIVHLRHIL QREGGWEAVC
610 620 630 640 650
DWKDVLSGGE KQRIGMARMF YHRPKYALLD ECTSAVSIDV EGKIFQAAKD
660 670 680 690 700
AGISLLSITH RPSLWKYHTH LLQFDGEGGW KFEKLDSAAR LSLTEEKQRL
710 720 730
EQQLAGIPKM QGRLQELRQI LGEAAAPVQP LVPGIPT
Length:737
Mass (Da):81,938
Last modified:April 20, 2010 - v1
Checksum:iC399AAE141153D23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096338 Genomic DNA. No translation available.
CH474099 Genomic DNA. Translation: EDL85026.1.
RefSeqiNP_001102291.1. NM_001108821.1.
UniGeneiRn.163453.

Genome annotation databases

EnsembliENSRNOT00000084088; ENSRNOP00000070359; ENSRNOG00000056524.
GeneIDi363516.
KEGGirno:363516.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096338 Genomic DNA. No translation available.
CH474099 Genomic DNA. Translation: EDL85026.1.
RefSeqiNP_001102291.1. NM_001108821.1.
UniGeneiRn.163453.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000084088; ENSRNOP00000070359; ENSRNOG00000056524.
GeneIDi363516.
KEGGirno:363516.

Organism-specific databases

CTDi215.
RGDi1562128. Abcd1.

Phylogenomic databases

eggNOGiKOG0064. Eukaryota.
COG4178. LUCA.
GeneTreeiENSGT00390000003950.
KOiK05675.
OMAiPRVLCRE.

Enzyme and pathway databases

ReactomeiR-RNO-1369062. ABC transporters in lipid homeostasis.
R-RNO-2046105. Linoleic acid (LA) metabolism.
R-RNO-2046106. alpha-linolenic acid (ALA) metabolism.
R-RNO-390247. Beta-oxidation of very long chain fatty acids.

Miscellaneous databases

NextBioi683546.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR031237. ALDP.
IPR005283. FA_transporter.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11384:SF21. PTHR11384:SF21. 1 hit.
PfamiPF06472. ABC_membrane_2. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00954. 3a01203. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUN-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZHR2_RAT
AccessioniPrimary (citable) accession number: D3ZHR2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 11, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.