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Protein
Submitted name:

Serum response factor

Gene

Srf

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-RNO-5663220. RHO GTPases Activate Formins.

Names & Taxonomyi

Protein namesi
Submitted name:
Serum response factorImported
Submitted name:
Similar to serum response factor (Predicted)Imported
Gene namesi
Name:SrfImported
Synonyms:RGD1559787_predictedImported
ORF Names:rCG_43683Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1559787. Srf.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

  • cytoplasm Source: Ensembl
  • nuclear chromatin Source: Ensembl
  • nucleus Source: RGD

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000018232.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000058149.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini137 – 197MADS-boxInterPro annotationAdd BLAST61

Phylogenomic databases

eggNOGiKOG0015. Eukaryota.
COG5068. LUCA.
GeneTreeiENSGT00400000022158.
KOiK04378.
OMAiNAFPQAP.
OrthoDBiEOG091G0X24.
TreeFamiTF318482.

Family and domain databases

CDDicd00266. MADS_SRF_like. 1 hit.
Gene3Di3.40.1810.10. 1 hit.
InterProiView protein in InterPro
IPR033897. MADS_SRF-like.
IPR002100. TF_MADSbox.
PfamiView protein in Pfam
PF00319. SRF-TF. 1 hit.
PRINTSiPR00404. MADSDOMAIN.
SMARTiView protein in SMART
SM00432. MADS. 1 hit.
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiView protein in PROSITE
PS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZHH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPSQAGAAA ALGRGSALGG SLNRTPTGRP GGSGGTRGAN GGRVPGNGAG
60 70 80 90 100
LGPGRLEREA AAAAAPTAGA LYSGSEGDSE SGEEEELGAE RRGLKRSLSE
110 120 130 140 150
MELGVVVGGP EAAAAAAGGY GPVSGAVSGA KPGKKTRGRV KIKMEFIDNK
160 170 180 190 200
LRRYTTFSKR KTGIMKKAYE LSTLTGTQVL LLVASETGHV YTFATRKLQP
210 220 230 240 250
MITSETGKAL IQTCLNSPDS PPRSDPSTDQ RMSATGFEEP DLTYQVSESD
260 270 280 290 300
SSGETKDTLK PAFTVTNLPG TTSTIQTAPS TSTTMQVSSG PSFPITNYLA
310 320 330 340 350
PVSASVSPSA VSSANGTVLK STGSGPVSSG GLMQLPTSFT LMPGGAVAQQ
360 370 380 390 400
VPVQAIHVHQ APQQASPSRD SSTDLTQTSS SGTVTLPATI MTSSVPTTVG
410 420 430 440 450
GHMMYPSPHA VMYAPTSGLA DGSLTVLNAF SQAPSTMQVS HSQVQEPGGV
460 470 480 490 500
PQVFLTAPSG TVQIPVSAVQ LHQMAVIGQQ AGSSSNLTEL QVVNLDATHS

TKSE
Length:504
Mass (Da):51,175
Last modified:April 3, 2013 - v2
Checksum:i814091FD4CAF8918
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07066803 Genomic DNA. No translation available.
CH473987 Genomic DNA. Translation: EDM18828.1.
RefSeqiNP_001102772.1. NM_001109302.1.
XP_006244619.1. XM_006244557.3.
UniGeneiRn.1501.

Genome annotation databases

EnsembliENSRNOT00000061430; ENSRNOP00000058149; ENSRNOG00000018232.
GeneIDi501099.
KEGGirno:501099.
UCSCiRGD:1559787. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD3ZHH8_RAT
AccessioniPrimary (citable) accession number: D3ZHH8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: June 7, 2017
This is version 67 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported