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Protein
Submitted name:

Ectodysplasin-A receptor

Gene

Edar

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-5669034 TNFs bind their physiological receptors

Names & Taxonomyi

Protein namesi
Submitted name:
Ectodysplasin-A receptorImported
Gene namesi
Name:EdarImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi

Organism-specific databases

RGDi1561714 Edar

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei184 – 210HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500305332627 – 448Sequence analysisAdd BLAST422

Proteomic databases

PaxDbiD3ZGP2

Expressioni

Gene expression databases

BgeeiENSRNOG00000028598

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000029258

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGTD Eukaryota
ENOG41104RU LUCA
GeneTreeiENSGT00730000111254
InParanoidiD3ZGP2
KOiK05162
OMAiGYQICRR
OrthoDBiEOG091G0ADI
PhylomeDBiD3ZGP2
TreeFamiTF331385

Family and domain databases

CDDicd13421 TNFRSF_EDAR, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR034052 EDAR_N
SUPFAMiSSF47986 SSF47986, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZGP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHVGDCKWM SWLPVLVVSL MCSAKAEDSN CGENEYHNQT TGLCQQCPPC
60 70 80 90 100
RPGEEPYMSC GYGTKDEDYG CVPCPAEKFS KGGYQICRRH KDCEGFFRAT
110 120 130 140 150
VLTPGDMEND AECGPCLPGY YMLENRPRNI YGMVCYSCLL APPNTKECVG
160 170 180 190 200
ATSGVSAHSS STSGGSTLSP FQHAHKELSS QGHLATALII AMSTIFIMAI
210 220 230 240 250
AIVLIIMFYI MKTKPSAPAC CSSPPGKSAE APANTHEEKK EAPDSVVTFP
260 270 280 290 300
ENGEFQKLTA TPTKTPKSEN DASSENEQLL SRSVDSDEEP APDKQGSPEL
310 320 330 340 350
CLLSLVHLAR EKSVASNKSA GIQSRRKKIL DVYANVCGVV EGLSPTELPF
360 370 380 390 400
DCLEKTSRML SSTYNSEKAV VKTWRHLAES FGLKRDEIGG MTDGMQLFDR
410 420 430 440
ISTAGYSIPE LLTKLVQIER LDAVESLCAD ILEWAGVVPP ASPPPAAS
Length:448
Mass (Da):48,448
Last modified:April 20, 2010 - v1
Checksum:i47510CEFA612B21D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07044956 Genomic DNA No translation available.
AABR07044957 Genomic DNA No translation available.
AABR07044958 Genomic DNA No translation available.
RefSeqiNP_001178828.1, NM_001191899.1
XP_006256443.1, XM_006256381.3
UniGeneiRn.133578

Genome annotation databases

EnsembliENSRNOT00000030348; ENSRNOP00000029258; ENSRNOG00000028598
GeneIDi365581
KEGGirno:365581
UCSCiRGD:1561714 rat

Entry informationi

Entry nameiD3ZGP2_RAT
AccessioniPrimary (citable) accession number: D3ZGP2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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