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Protein
Submitted name:

Protein Spcs1

Gene

Spcs1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. peptidase activity Source: InterPro
  2. ribosome binding Source: Ensembl

GO - Biological processi

  1. protein targeting to ER Source: GO_Central
  2. signal peptide processing Source: GO_Central
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_233679. Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP).
REACT_246486. Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1).
REACT_250291. Synthesis, secretion, and deacylation of Ghrelin.
REACT_258344. SRP-dependent cotranslational protein targeting to membrane.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Spcs1Imported
Gene namesi
Name:Spcs1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 16

Organism-specific databases

RGDi1309125. Spcs1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of endoplasmic reticulum membrane Source: GO_Central
  2. signal peptidase complex Source: GO_Central
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD3ZFK5.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000018321.
InParanoidiD3ZFK5.
KOiK12946.
OMAiNKHPVKW.
OrthoDBiEOG73FQNV.
TreeFamiTF106122.

Family and domain databases

InterProiIPR009542. SPC12.
[Graphical view]
PANTHERiPTHR13202. PTHR13202. 1 hit.
PfamiPF06645. SPC12. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZFK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEHLSSLPT QMDYKGQKLA EQMFQGIILF SAIVGFIYGY VAEQFGWTVY
60 70 80 90 100
IVMAGFAFSC LLTLPPWPIY RRHPLKWLPV QDSGTEDKKS GDRKIKRHAK

NN
Length:102
Mass (Da):11,751
Last modified:April 3, 2013 - v2
Checksum:iEB178217442A32A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06086373 Genomic DNA. No translation available.
RefSeqiNP_001124478.1. NM_001131006.1.
UniGeneiRn.3781.

Genome annotation databases

EnsembliENSRNOT00000024447; ENSRNOP00000024447; ENSRNOG00000018075.
GeneIDi290555.
KEGGirno:290555.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06086373 Genomic DNA. No translation available.
RefSeqiNP_001124478.1. NM_001131006.1.
UniGeneiRn.3781.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD3ZFK5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000024447; ENSRNOP00000024447; ENSRNOG00000018075.
GeneIDi290555.
KEGGirno:290555.

Organism-specific databases

CTDi28972.
RGDi1309125. Spcs1.

Phylogenomic databases

GeneTreeiENSGT00390000018321.
InParanoidiD3ZFK5.
KOiK12946.
OMAiNKHPVKW.
OrthoDBiEOG73FQNV.
TreeFamiTF106122.

Enzyme and pathway databases

ReactomeiREACT_233679. Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP).
REACT_246486. Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1).
REACT_250291. Synthesis, secretion, and deacylation of Ghrelin.
REACT_258344. SRP-dependent cotranslational protein targeting to membrane.

Miscellaneous databases

NextBioi35567149.

Family and domain databases

InterProiIPR009542. SPC12.
[Graphical view]
PANTHERiPTHR13202. PTHR13202. 1 hit.
PfamiPF06645. SPC12. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZFK5_RAT
AccessioniPrimary (citable) accession number: D3ZFK5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: March 4, 2015
This is version 39 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.