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D3ZEY4

- D3ZEY4_RAT

UniProt

D3ZEY4 - D3ZEY4_RAT

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Protein

Diacylglycerol kinase

Gene
Dgkq, rCG_57232
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. diacylglycerol kinase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW
  4. NAD+ kinase activity Source: InterPro

GO - Biological processi

  1. cAMP-mediated signaling Source: Ensembl
  2. protein kinase C-activating G-protein coupled receptor signaling pathway Source: InterPro
  3. protein kinase C signaling Source: Ensembl
  4. response to ATP Source: Ensembl
  5. thrombin receptor signaling pathway Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinaseUniRule annotation (EC:2.7.1.107UniRule annotation)
Short name:
DAG kinaseUniRule annotation
Gene namesi
Name:DgkqImported
ORF Names:rCG_57232Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 14

Organism-specific databases

RGDi2320722. Dgkq.

Subcellular locationi

GO - Cellular componenti

  1. cytoskeleton Source: Ensembl
  2. cytosol Source: Ensembl
  3. nuclear speck Source: Ensembl
  4. plasma membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Contains 1 DAGKc domain.UniRule annotation
Contains 2 Ras-associating domains.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117493.
KOiK00901.
OMAiSDFIWGL.
OrthoDBiEOG71VSS6.
TreeFamiTF312817.

Family and domain databases

InterProiIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR020454. DAG/PE-bd.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
IPR000159. Ras-assoc.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00130. C1_1. 2 hits.
PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
PF00788. RA. 2 hits.
[Graphical view]
PRINTSiPR00008. DAGPEDOMAIN.
SMARTiSM00109. C1. 3 hits.
SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
SM00314. RA. 1 hit.
[Graphical view]
SUPFAMiSSF111331. SSF111331. 1 hit.
SSF54236. SSF54236. 2 hits.
PROSITEiPS50146. DAGK. 1 hit.
PS50200. RA. 1 hit.
PS00479. ZF_DAG_PE_1. 3 hits.
PS50081. ZF_DAG_PE_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZEY4-1 [UniParc]FASTAAdd to Basket

« Hide

MATAAESGAR TWPGSGSPRL GSPAGSPVLG ISGRARPGSG PERTGRAIGS    50
VAPGHSFRKV TLTKPTFCHL CSDFIWGLAG FLCDVCNFMS HEKCLKQVKT 100
PCTSIAPSLV RVPVAHCFGS LGLYKRKFCV VCRKSLEVPA FRCEVCELHV 150
HPDCVPFACS DCRQCHQDGQ HDYDTYHHHW REGNLPSGAR CEVCRKTCGS 200
SDVLAGVRCE WCGVQAHSVC STALTPECTF GRLRSMVLPP SCVRLLSRNF 250
SKMHCFRIPE TMVLELGDGD DGLDGSAAVG TGREVSAATE STKQTLKIFD 300
GNDSMRKNQF RLVTVSRLAR NEEVMEAALR AYYINEDPKD FQLQALPLTL 350
LSGNAQALGK AGTTEEETSK DSGPGDSVPE AWVIRSLPRT QEILKIYPDW 400
LKVGVAYVSI RVNSQSTARS VVQEVLPLFG RQVEDQERFQ LIEVLMSSRQ 450
VQRTVLVDEE PLLDRLRDIR QTSVRQASQT RFYVAEARAV TPHVSLFVGG 500
LPPGLSPQDY SNLLHEAMAT KAAVVSVSHV YSLQGAVVLD VTCFAEAERL 550
YMLARDTAVH GRPLTALVLP DVLHTKLPPD CCPLLVFVNP KSGGLKGREL 600
LCSFRKLLNP HQVFELTNGG PLPGFHLFSQ VPCFRVLVCG GDGTVGWVLA 650
ALEETRRHLA CPEPSVAILP LGTGNDLGRV LRWGAGYSGE DPFSVLVSVD 700
EADAVLMDRW TILLDAHEID STENNVVETE PPKIVQMNNY CGIGIDAELS 750
LDFHQAREEE PGKFTSRFHN KGVYVRVGLQ KISHSRSLHK EIRLQVEQQE 800
VELPSIEGLI FINIPSWGSG ADLWGSDSDS RFEKPRIDDG LLEVVGVTGV 850
VHMGQVQGGL RSGIRIAQGS YFRVTLLKAT PVQVDGEPWI QAPGHMIISA 900
TAPKVHMLRK AKQKPRKAGA IRDTRVDTLP APEGNPL 937
Length:937
Mass (Da):102,545
Last modified:April 20, 2010 - v1
Checksum:i9E0EAEAFD5A99716
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06077222 Genomic DNA. No translation available.
CH474079 Genomic DNA. Translation: EDL84024.1.
RefSeqiNP_001185733.1. NM_001198804.1.
UniGeneiRn.101434.

Genome annotation databases

EnsembliENSRNOT00000032056; ENSRNOP00000036466; ENSRNOG00000024112.
GeneIDi100361138.
KEGGirno:100361138.
UCSCiRGD:2320722. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06077222 Genomic DNA. No translation available.
CH474079 Genomic DNA. Translation: EDL84024.1 .
RefSeqi NP_001185733.1. NM_001198804.1.
UniGenei Rn.101434.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000032056 ; ENSRNOP00000036466 ; ENSRNOG00000024112 .
GeneIDi 100361138.
KEGGi rno:100361138.
UCSCi RGD:2320722. rat.

Organism-specific databases

CTDi 1609.
RGDi 2320722. Dgkq.

Phylogenomic databases

GeneTreei ENSGT00750000117493.
KOi K00901.
OMAi SDFIWGL.
OrthoDBi EOG71VSS6.
TreeFami TF312817.

Miscellaneous databases

NextBioi 34066233.
PROi D3ZEY4.

Family and domain databases

InterProi IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR020454. DAG/PE-bd.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
IPR000159. Ras-assoc.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF00130. C1_1. 2 hits.
PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
PF00788. RA. 2 hits.
[Graphical view ]
PRINTSi PR00008. DAGPEDOMAIN.
SMARTi SM00109. C1. 3 hits.
SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
SM00314. RA. 1 hit.
[Graphical view ]
SUPFAMi SSF111331. SSF111331. 1 hit.
SSF54236. SSF54236. 2 hits.
PROSITEi PS50146. DAGK. 1 hit.
PS50200. RA. 1 hit.
PS00479. ZF_DAG_PE_1. 3 hits.
PS50081. ZF_DAG_PE_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZEY4_RAT
AccessioniPrimary (citable) accession number: D3ZEY4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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