Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Diacylglycerol kinase

Gene

Dgkq

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-114508. Effects of PIP2 hydrolysis.

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinaseUniRule annotation (EC:2.7.1.107UniRule annotation)
Short name:
DAG kinaseUniRule annotation
Gene namesi
Name:DgkqImported
ORF Names:rCG_57232Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi2320722. Dgkq.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PeptideAtlasiD3ZEY4.

PTM databases

PhosphoSitePlusiD3ZEY4.

Expressioni

Gene expression databases

BgeeiENSRNOG00000024112.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000036466.

Structurei

3D structure databases

ProteinModelPortaliD3ZEY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 102Phorbol-ester/DAG-typeInterPro annotationAdd BLAST49
Domaini115 – 162Phorbol-ester/DAG-typeInterPro annotationAdd BLAST48
Domaini177 – 228Phorbol-ester/DAG-typeInterPro annotationAdd BLAST52
Domaini390 – 489Ras-associatingInterPro annotationAdd BLAST100
Domaini579 – 716DAGKcInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the eukaryotic diacylglycerol kinase family.UniRule annotation
Contains 1 DAGKc domain.UniRule annotation
Contains 1 Ras-associating domain.UniRule annotation
Contains 3 phorbol-ester/DAG-type zinc fingers.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1169. Eukaryota.
ENOG410XQVB. LUCA.
GeneTreeiENSGT00760000119050.
KOiK00901.
OMAiTKPTFCH.
OrthoDBiEOG091G02NN.
PhylomeDBiD3ZEY4.
TreeFamiTF312817.

Family and domain databases

CDDicd00029. C1. 2 hits.
InterProiIPR020454. DAG/PE-bd.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR016064. NAD/diacylglycerol_kinase.
IPR002219. PE/DAG-bd.
IPR000159. RA_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00130. C1_1. 2 hits.
PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
PF00788. RA. 1 hit.
[Graphical view]
PRINTSiPR00008. DAGPEDOMAIN.
SMARTiSM00109. C1. 3 hits.
SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
SM00314. RA. 1 hit.
[Graphical view]
SUPFAMiSSF111331. SSF111331. 1 hit.
SSF54236. SSF54236. 2 hits.
PROSITEiPS50146. DAGK. 1 hit.
PS50200. RA. 1 hit.
PS00479. ZF_DAG_PE_1. 3 hits.
PS50081. ZF_DAG_PE_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZEY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAAESGAR TWPGSGSPRL GSPAGSPVLG ISGRARPGSG PERTGRAIGS
60 70 80 90 100
VAPGHSFRKV TLTKPTFCHL CSDFIWGLAG FLCDVCNFMS HEKCLKQVKT
110 120 130 140 150
PCTSIAPSLV RVPVAHCFGS LGLYKRKFCV VCRKSLEVPA FRCEVCELHV
160 170 180 190 200
HPDCVPFACS DCRQCHQDGQ HDYDTYHHHW REGNLPSGAR CEVCRKTCGS
210 220 230 240 250
SDVLAGVRCE WCGVQAHSVC STALTPECTF GRLRSMVLPP SCVRLLSRNF
260 270 280 290 300
SKMHCFRIPE TMVLELGDGD DGLDGSAAVG TGREVSAATE STKQTLKIFD
310 320 330 340 350
GNDSMRKNQF RLVTVSRLAR NEEVMEAALR AYYINEDPKD FQLQALPLTL
360 370 380 390 400
LSGNAQALGK AGTTEEETSK DSGPGDSVPE AWVIRSLPRT QEILKIYPDW
410 420 430 440 450
LKVGVAYVSI RVNSQSTARS VVQEVLPLFG RQVEDQERFQ LIEVLMSSRQ
460 470 480 490 500
VQRTVLVDEE PLLDRLRDIR QTSVRQASQT RFYVAEARAV TPHVSLFVGG
510 520 530 540 550
LPPGLSPQDY SNLLHEAMAT KAAVVSVSHV YSLQGAVVLD VTCFAEAERL
560 570 580 590 600
YMLARDTAVH GRPLTALVLP DVLHTKLPPD CCPLLVFVNP KSGGLKGREL
610 620 630 640 650
LCSFRKLLNP HQVFELTNGG PLPGFHLFSQ VPCFRVLVCG GDGTVGWVLA
660 670 680 690 700
ALEETRRHLA CPEPSVAILP LGTGNDLGRV LRWGAGYSGE DPFSVLVSVD
710 720 730 740 750
EADAVLMDRW TILLDAHEID STENNVVETE PPKIVQMNNY CGIGIDAELS
760 770 780 790 800
LDFHQAREEE PGKFTSRFHN KGVYVRVGLQ KISHSRSLHK EIRLQVEQQE
810 820 830 840 850
VELPSIEGLI FINIPSWGSG ADLWGSDSDS RFEKPRIDDG LLEVVGVTGV
860 870 880 890 900
VHMGQVQGGL RSGIRIAQGS YFRVTLLKAT PVQVDGEPWI QAPGHMIISA
910 920 930
TAPKVHMLRK AKQKPRKAGA IRDTRVDTLP APEGNPL
Length:937
Mass (Da):102,545
Last modified:April 20, 2010 - v1
Checksum:i9E0EAEAFD5A99716
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117047 Genomic DNA. No translation available.
CH474079 Genomic DNA. Translation: EDL84024.1.
RefSeqiNP_001185733.1. NM_001198804.1.
UniGeneiRn.101434.

Genome annotation databases

EnsembliENSRNOT00000032056; ENSRNOP00000036466; ENSRNOG00000024112.
GeneIDi100361138.
KEGGirno:100361138.
UCSCiRGD:2320722. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117047 Genomic DNA. No translation available.
CH474079 Genomic DNA. Translation: EDL84024.1.
RefSeqiNP_001185733.1. NM_001198804.1.
UniGeneiRn.101434.

3D structure databases

ProteinModelPortaliD3ZEY4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000036466.

PTM databases

PhosphoSitePlusiD3ZEY4.

Proteomic databases

PeptideAtlasiD3ZEY4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000032056; ENSRNOP00000036466; ENSRNOG00000024112.
GeneIDi100361138.
KEGGirno:100361138.
UCSCiRGD:2320722. rat.

Organism-specific databases

CTDi1609.
RGDi2320722. Dgkq.

Phylogenomic databases

eggNOGiKOG1169. Eukaryota.
ENOG410XQVB. LUCA.
GeneTreeiENSGT00760000119050.
KOiK00901.
OMAiTKPTFCH.
OrthoDBiEOG091G02NN.
PhylomeDBiD3ZEY4.
TreeFamiTF312817.

Enzyme and pathway databases

ReactomeiR-RNO-114508. Effects of PIP2 hydrolysis.

Gene expression databases

BgeeiENSRNOG00000024112.

Family and domain databases

CDDicd00029. C1. 2 hits.
InterProiIPR020454. DAG/PE-bd.
IPR000756. Diacylglycerol_kin_accessory.
IPR001206. Diacylglycerol_kinase_cat_dom.
IPR016064. NAD/diacylglycerol_kinase.
IPR002219. PE/DAG-bd.
IPR000159. RA_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00130. C1_1. 2 hits.
PF00609. DAGK_acc. 1 hit.
PF00781. DAGK_cat. 1 hit.
PF00788. RA. 1 hit.
[Graphical view]
PRINTSiPR00008. DAGPEDOMAIN.
SMARTiSM00109. C1. 3 hits.
SM00045. DAGKa. 1 hit.
SM00046. DAGKc. 1 hit.
SM00314. RA. 1 hit.
[Graphical view]
SUPFAMiSSF111331. SSF111331. 1 hit.
SSF54236. SSF54236. 2 hits.
PROSITEiPS50146. DAGK. 1 hit.
PS50200. RA. 1 hit.
PS00479. ZF_DAG_PE_1. 3 hits.
PS50081. ZF_DAG_PE_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZEY4_RAT
AccessioniPrimary (citable) accession number: D3ZEY4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 30, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.