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Protein
Submitted name:

Histone methyltransferase Pr-set7/Set8

Gene

Kmt5a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseImported, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-2299718. Condensation of Prophase Chromosomes.
R-RNO-3214841. PKMTs methylate histone lysines.
R-RNO-6804760. Regulation of TP53 Activity through Methylation.

Names & Taxonomyi

Protein namesi
Submitted name:
Histone methyltransferase Pr-set7/Set8Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Kmt5aImported
Synonyms:LOC100909949Imported, Pr-set7Imported, Setd8Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1587560. Kmt5a.

Expressioni

Gene expression databases

BgeeiENSRNOG00000001062.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000062763.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini186 – 307122SETInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG1085. Eukaryota.
COG2940. LUCA.
GeneTreeiENSGT00410000025501.
KOiK11428.
OMAiKQFSRGE.
OrthoDBiEOG091G0UBI.

Family and domain databases

InterProiIPR016858. Hist_H4-K20_MeTrfase.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
PIRSFiPIRSF027717. Histone_H4-K20_mtfrase. 1 hit.
SMARTiSM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51571. SAM_MT43_PR_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZEB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVERRGPGRP RSDGENVFAG QSKIYAYMSP NKCSGMRSPL QEENSVAHHE
60 70 80 90 100
VKCPGKPLAG IYRKREEKRN AGNVIRSAVK SEEQKSKDTR RGPLAPFPNQ
110 120 130 140 150
KPEATEPPKT PPPSCDSTSV AVAKQALKKP LKGKQAPRKK SQGKTQQNRK
160 170 180 190 200
LTDFYPVRRS SRKSKAELQS EERKKIDELI ESGKEEGMKI DLIDGKGRGV
210 220 230 240 250
IATKRFSRGD FVVEYHGDLI EITDAKKREA LYAQDPSTGC YMYYFQYLSK
260 270 280 290 300
TYCVDATQET NRLGRLINHS KCGNCQTKLH DIDGVPHLIL IASRDIAAGE
310 320
ELLYDYGDRS KASIEAYPWL KH
Length:322
Mass (Da):36,216
Last modified:April 3, 2013 - v2
Checksum:iBB07F0BC32F9A066
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036310 Genomic DNA. No translation available.
AABR07072291 Genomic DNA. No translation available.
AB606422 mRNA. Translation: BAK43219.1.
RefSeqiNP_001233594.1. NM_001246665.1.
UniGeneiRn.8879.

Genome annotation databases

EnsembliENSRNOT00000066253; ENSRNOP00000062763; ENSRNOG00000001062.
GeneIDi689820.
KEGGirno:689820.
UCSCiRGD:1587560. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036310 Genomic DNA. No translation available.
AABR07072291 Genomic DNA. No translation available.
AB606422 mRNA. Translation: BAK43219.1.
RefSeqiNP_001233594.1. NM_001246665.1.
UniGeneiRn.8879.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000062763.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000066253; ENSRNOP00000062763; ENSRNOG00000001062.
GeneIDi689820.
KEGGirno:689820.
UCSCiRGD:1587560. rat.

Organism-specific databases

CTDi387893.
RGDi1587560. Kmt5a.

Phylogenomic databases

eggNOGiKOG1085. Eukaryota.
COG2940. LUCA.
GeneTreeiENSGT00410000025501.
KOiK11428.
OMAiKQFSRGE.
OrthoDBiEOG091G0UBI.

Enzyme and pathway databases

ReactomeiR-RNO-2299718. Condensation of Prophase Chromosomes.
R-RNO-3214841. PKMTs methylate histone lysines.
R-RNO-6804760. Regulation of TP53 Activity through Methylation.

Gene expression databases

BgeeiENSRNOG00000001062.

Family and domain databases

InterProiIPR016858. Hist_H4-K20_MeTrfase.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
PIRSFiPIRSF027717. Histone_H4-K20_mtfrase. 1 hit.
SMARTiSM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51571. SAM_MT43_PR_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZEB9_RAT
AccessioniPrimary (citable) accession number: D3ZEB9
Secondary accession number(s): F7J138
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: September 7, 2016
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.