D3ZEB9 (D3ZEB9_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Histone methyltransferase Pr-set7/Set8 EMBL BAK43219.1

Submitted name:
Protein LOC100909949 Ensembl ENSRNOP00000062763

Gene names

Name:	Setd8 Ensembl ENSRNOP00000062763 RGD 1587560
Synonyms:	LOC100909949 Ensembl ENSRNOP00000062763, Pr-set7 EMBL BAK43219.1

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000062763

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SET domain. SAAS SAAS001214 RuleBase RU004538

Ontologies

Keywords
Molecular function	Methyltransferase EMBL BAK43219.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3ZEB9 [UniParc]. Last modified April 3, 2013. Version 2. Checksum: BB07F0BC32F9A066	FASTA	322	36,216
	10 20 30 40 50 60 MVERRGPGRP RSDGENVFAG QSKIYAYMSP NKCSGMRSPL QEENSVAHHE VKCPGKPLAG 70 80 90 100 110 120 IYRKREEKRN AGNVIRSAVK SEEQKSKDTR RGPLAPFPNQ KPEATEPPKT PPPSCDSTSV 130 140 150 160 170 180 AVAKQALKKP LKGKQAPRKK SQGKTQQNRK LTDFYPVRRS SRKSKAELQS EERKKIDELI 190 200 210 220 230 240 ESGKEEGMKI DLIDGKGRGV IATKRFSRGD FVVEYHGDLI EITDAKKREA LYAQDPSTGC 250 260 270 280 290 300 YMYYFQYLSK TYCVDATQET NRLGRLINHS KCGNCQTKLH DIDGVPHLIL IASRDIAAGE 310 320 ELLYDYGDRS KASIEAYPWL KH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000062763.
[2]	"Histone methyltransferase Pr-set7 represses the promoter activity of the tumor marker gene." Osada S., Hashizume H., Gomita U., Imagawa M. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Liver EMBL BAK43219.1.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000062763.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06071938 Genomic DNA. No translation available. AABR06071939 Genomic DNA. No translation available. AABR06071940 Genomic DNA. No translation available. AB606422 mRNA. Translation: BAK43219.1.
IPI	IPI00765769.
RefSeq	NP_001233594.1. NM_001246665.1.
UniGene	Rn.8879.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000066253; ENSRNOP00000062763; ENSRNOG00000001062.
GeneID	689820.
KEGG	rno:689820.
UCSC	RGD:1587560. rat.
Organism-specific databases
CTD	387893.
RGD	6501036. LOC100909949. 1587560. Setd8.
Phylogenomic databases
GeneTree	ENSGT00410000025501.
KO	K11428.
Family and domain databases
InterPro	IPR016858. Hist_H4-K20_MeTrfase. IPR001214. SET_dom. [Graphical view]
Pfam	PF00856. SET. 1 hit. [Graphical view]
PIRSF	PIRSF027717. Histone_H4-K20_mtfrase. 1 hit.
SMART	SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS51571. SAM_MT43_PR_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35566877.

Entry information

Entry name

D3ZEB9_RAT

Accession

Primary (citable) accession number: D3ZEB9
Secondary accession number(s): F7J138

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 3, 2013
Last modified:	May 1, 2013
This is version 24 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)