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Protein
Submitted name:

Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_a

Gene

Ifnar1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Enzyme and pathway databases

ReactomeiR-RNO-909733. Interferon alpha/beta signaling.
R-RNO-912694. Regulation of IFNA signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon (Alpha and beta) receptor 1 (Predicted), isoform CRA_aImported
Submitted name:
Interferon alpha and beta receptor subunit 1Imported
Gene namesi
Name:Ifnar1Imported
Synonyms:Ifnar1_predictedImported
ORF Names:rCG_58652Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 11

Organism-specific databases

RGDi1305399. Ifnar1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei432 – 451HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_501120498626 – 593Sequence analysisAdd BLAST568

Expressioni

Gene expression databases

BgeeiENSRNOG00000028594.
ExpressionAtlasiD3ZDS9. baseline and differential.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000031611.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 131Fibronectin type-IIIInterPro annotationAdd BLAST101
Domaini230 – 328Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini332 – 428Fibronectin type-IIIInterPro annotationAdd BLAST97

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IKIP. Eukaryota.
ENOG4111QEU. LUCA.
GeneTreeiENSGT00530000063449.
KOiK05130.
OMAiVYCVKAR.
OrthoDBiEOG091G04H5.
TreeFamiTF332537.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR036116. FN3_sf.
IPR013783. Ig-like_fold.
IPR015373. Interferon/interleukin_rcp_dom.
PfamiView protein in Pfam
PF09294. Interfer-bind. 2 hits.
PF01108. Tissue_fac. 1 hit.
SMARTiView protein in SMART
SM00060. FN3. 3 hits.
SUPFAMiSSF49265. SSF49265. 4 hits.
PROSITEiView protein in PROSITE
PS50853. FN3. 3 hits.

Sequencei

Sequence statusi: Complete.

D3ZDS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAVVGAAAL VLVAGAPWML PVASGEDNLR PPEDVAIYII DDNYTLKWNH
60 70 80 90 100
HRESMGNVTF SAEYQKGEGR IWLKVPKCQH ITRTKCEFSL LGINVYSKTQ
110 120 130 140 150
FRVRAEEGNS TSSWNEADSF IPFYKAHVSP PRVHLKAEDK AILVYISPPG
160 170 180 190 200
EDGTMWAQEK RCFNYTIRIW GRSFPVREIK PMYFPKKISK LLPETTYCLE
210 220 230 240 250
VRAVHTSLQR HSNYSSARCI NTTVANKIPV PENLEVDVQG DSYVLKWDHA
260 270 280 290 300
FANMTFKAQW IPVYSKSSPG NHSDKWKPIP TCANVQTTHC VSPRETFHTG
310 320 330 340 350
TFFLRVQASD GNNTSFWSEE KLIDSQKYTL LPPPVIAVTP TGDSLLVYVS
360 370 380 390 400
CKDSKCNGLI YEVIFWENTS NTEKRQHPQS MIKEHPEFNV VNLRPLTVYC
410 420 430 440 450
VQARVLSTGV WNKTSKFSDK LCKKTHPGNS SVTWIITGFG ALLFSAMAFY
460 470 480 490 500
AGRSLQKYLY YVFSPPLKPP CSIDEFFSEL PSKSLLLLTA EEHTERCFVI
510 520 530 540 550
ENTGVVAGEE NRAPEEELRK YSSQSSQDSG NYSNEEEESV GPESGQDMLS
560 570 580 590
TAPSGSPWSL PCPAGTLEDG ACFPGKEKHL QSPVLRTQPA LHG
Length:593
Mass (Da):66,591
Last modified:July 22, 2015 - v2
Checksum:i082C0260B7CF5B81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120974 Genomic DNA. No translation available.
CH473989 Genomic DNA. Translation: EDM10721.1.
RefSeqiNP_001099363.2. NM_001105893.1.
UniGeneiRn.105738.

Genome annotation databases

EnsembliENSRNOT00000029985; ENSRNOP00000031611; ENSRNOG00000028594.
GeneIDi288264.
KEGGirno:288264.
UCSCiRGD:1305399. rat.

Similar proteinsi

Entry informationi

Entry nameiD3ZDS9_RAT
AccessioniPrimary (citable) accession number: D3ZDS9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: December 20, 2017
This is version 67 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported