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Protein
Submitted name:

Neuroligin-3

Gene

Nlgn3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-6794361. Neurexins and neuroligins.

Protein family/group databases

ESTHERiratno-3neur. Neuroligin.

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroligin-3Imported
Gene namesi
Name:Nlgn3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi621119. Nlgn3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei688 – 711HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 37Sequence analysisAdd BLAST37
ChainiPRO_500305275238 – 828Sequence analysisAdd BLAST791

Proteomic databases

PaxDbiD3ZDC0.

Expressioni

Gene expression databases

BgeeiENSRNOG00000003812.
ExpressionAtlasiD3ZDC0. baseline.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 604COesteraseInterPro annotationAdd BLAST564

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1516. Eukaryota.
COG2272. LUCA.
GeneTreeiENSGT00760000118946.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019819. Carboxylesterase_B_CS.
IPR000460. Nlgn.
IPR030024. NLGN3.
PANTHERiPTHR43903:SF4. PTHR43903:SF4. 1 hit.
PfamiView protein in Pfam
PF00135. COesterase. 1 hit.
PRINTSiPR01090. NEUROLIGIN.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiView protein in PROSITE
PS00941. CARBOXYLESTERASE_B_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D3ZDC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLQLGLPSL SLSPTPTVGR SLCLILWFLS LVLRASTQAP APTVNTHFGK
60 70 80 90 100
LRGARVPLPS EILGPVDQYL GVPYAAPPIG EKRFLPPEPP PSWSGIRNAT
110 120 130 140 150
HFPPVCPQNI HTAVPEVMLP VWFTANLDIV ATYIQEPNED CLYLNVYVPT
160 170 180 190 200
EDGSGAKKQG EDLADNDGDE DEDIRDSGAK PVMVYIHGGS YMEGTGNMID
210 220 230 240 250
GSVLASYGNV IVITLNYRVG VLGFLSTGDQ AAKGNYGLLD QIQALRWVSE
260 270 280 290 300
NIAFFGGDPR RITVFGSGIG ASCVSLLTLS HHSEGLFQRA IIQSGSALSS
310 320 330 340 350
WAVNYQPVKY TSLLADKVGC NVLDTVDMVD CLRQKSAKEL VEQDIQPARY
360 370 380 390 400
HVAFGPVIDG DVIPDDPEIL MEQGEFLNYD IMLGVNQGEG LKFVEGVVDP
410 420 430 440 450
EDGVSGTDFD YSVSNFVDNL YGYPEGKDTL RETIKFMYTD WADRDNPETR
460 470 480 490 500
RKTLVALFTD HQWVEPSVVT ADLHARYGSP TYFYAFYHHC QSLMKPAWSD
510 520 530 540 550
AAHGDEVPYV FGVPMVGPTD LFPCNFSKND VMLSAVVMTY WTNFAKTGDP
560 570 580 590 600
NKPVPQDTKF IHTKANRFEE VAWSKYNPRD QLYLHIGLKP RVRDHYRATK
610 620 630 640 650
VAFWKHLVPH LYNLHDMFHY TSTTTKVPPP DTTHSSHITR RPNGKTWSTK
660 670 680 690 700
RPAISPAYSN ENAPGSWNGD QDAGPLLVEN PRDYSTELSV TIAVGASLLF
710 720 730 740 750
LNVLAFAALY YRKDKRRQEP LRQPSPQRGT GAPELGTAPE EELAALQLGP
760 770 780 790 800
THHECEAGPP HDTLRLTALP DYTLTLRRSP DDIPLMTPNT ITMIPNSLVG
810 820
LQTLHPYNTF AAGFNSTGLP HSHSTTRV
Length:828
Mass (Da):91,586
Last modified:April 20, 2010 - v1
Checksum:i3812DF45CF916C8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07039195 Genomic DNA. No translation available.
RefSeqiXP_006257116.1. XM_006257054.3.
UniGeneiRn.226139.

Genome annotation databases

EnsembliENSRNOT00000005102; ENSRNOP00000005102; ENSRNOG00000003812.
GeneIDi171297.

Similar proteinsi

Entry informationi

Entry nameiD3ZDC0_RAT
AccessioniPrimary (citable) accession number: D3ZDC0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 25, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported