ID   D3ZD09_RAT              Unreviewed;        97 AA.
AC   D3ZD09;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 2.
DT   27-MAR-2024, entry version 102.
DE   RecName: Full=Cytochrome c oxidase subunit 6B1 {ECO:0000256|ARBA:ARBA00040060};
DE   AltName: Full=Cytochrome c oxidase subunit VIb isoform 1 {ECO:0000256|ARBA:ARBA00042114};
GN   Name=LOC120103152 {ECO:0000313|Ensembl:ENSRNOP00000048723.3,
GN   ECO:0000313|RGD:40933017};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000048723.3, ECO:0000313|Proteomes:UP000002494};
RN   [1] {ECO:0000313|Ensembl:ENSRNOP00000048723.3, ECO:0000313|Proteomes:UP000002494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000048723.3,
RC   ECO:0000313|Proteomes:UP000002494};
RX   PubMed=15057822; DOI=10.1038/nature02426;
RG   Rat Genome Sequencing Project Consortium;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA   Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA   Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA   Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA   Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA   Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA   Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA   Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA   Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA   Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA   Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA   Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA   Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA   Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA   Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA   Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA   Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA   Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA   Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA   Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA   Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA   Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA   Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA   Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA   Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA   Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA   Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA   Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA   Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA   Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA   Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA   Mockrin S., Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into mammalian
RT   evolution.";
RL   Nature 428:493-521(2004).
RN   [2] {ECO:0000313|Ensembl:ENSRNOP00000048723.3}
RP   IDENTIFICATION.
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000048723.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; D3ZD09; -.
DR   STRING; 10116.ENSRNOP00000048723; -.
DR   CarbonylDB; D3ZD09; -.
DR   jPOST; D3ZD09; -.
DR   PaxDb; 10116-ENSRNOP00000030997; -.
DR   PeptideAtlas; D3ZD09; -.
DR   Ensembl; ENSRNOT00000045155.5; ENSRNOP00000048723.3; ENSRNOG00000034161.5.
DR   UCSC; RGD:1584097; rat.
DR   AGR; RGD:40933017; -.
DR   RGD; 40933017; LOC120103152.
DR   VEuPathDB; HostDB:ENSRNOG00000034161; -.
DR   eggNOG; KOG3057; Eukaryota.
DR   GeneTree; ENSGT00940000156204; -.
DR   HOGENOM; CLU_133964_3_2_1; -.
DR   InParanoid; D3ZD09; -.
DR   OMA; IFARDCK; -.
DR   OrthoDB; 555936at2759; -.
DR   PhylomeDB; D3ZD09; -.
DR   TreeFam; TF105065; -.
DR   Reactome; R-RNO-5628897; TP53 Regulates Metabolic Genes.
DR   Reactome; R-RNO-611105; Respiratory electron transport.
DR   Reactome; R-RNO-9707564; Cytoprotection by HMOX1.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Bgee; ENSRNOG00000034161; Expressed in quadriceps femoris and 18 other cell types or tissues.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0045277; C:respiratory chain complex IV; IEA:InterPro.
DR   CDD; cd00926; Cyt_c_Oxidase_VIb; 1.
DR   Gene3D; 1.10.10.140; Cytochrome c oxidase, subunit VIb; 1.
DR   InterPro; IPR048280; COX6B-like.
DR   InterPro; IPR003213; Cyt_c_oxidase_su6B.
DR   InterPro; IPR036549; Cyt_c_oxidase_su6B_sf.
DR   PANTHER; PTHR11387; CYTOCHROME C OXIDASE SUBUNIT 6B; 1.
DR   PANTHER; PTHR11387:SF16; CYTOCHROME C OXIDASE SUBUNIT 6B1; 1.
DR   Pfam; PF02297; COX6B; 1.
DR   PIRSF; PIRSF000278; Cyt_c_oxidase_6B; 1.
DR   SUPFAM; SSF47694; Cytochrome c oxidase subunit h; 1.
DR   PROSITE; PS51808; CHCH; 1.
PE   1: Evidence at protein level;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW   ECO:0000256|PIRSR:PIRSR000278-1};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Proteomics identification {ECO:0007829|PeptideAtlas:D3ZD09};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT   DISULFID        30..65
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000278-1"
FT   DISULFID        40..54
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000278-1"
SQ   SEQUENCE   97 AA;  11251 MW;  6C778527EF8B07DD CRC64;
     MAEEIKIKIK NYKTAPFDSR FPNQNQTKNC WQNYLDFRHC EKAMTAKGGD VSVCEWYRRV
     YKSLCPVSWV SAWDDRIAEG TFPGKIRPGS AHLSYAL
//