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Protein
Submitted name:

Protein Rfx8

Gene

Rfx8

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: GO_Central
  2. sequence-specific DNA binding transcription factor activity Source: GO_Central

GO - Biological processi

  1. endocrine pancreas development Source: GO_Central
  2. regulation of transcription from RNA polymerase II promoter Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Rfx8Imported
Gene namesi
Name:Rfx8Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1560724. Rfx8.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: GO_Central
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074532.
InParanoidiD3ZCQ8.
OMAiDNFCICE.
OrthoDBiEOG74BJRM.
TreeFamiTF342109.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR003150. DNA-bd_RFX.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF02257. RFX_DNA_binding. 1 hit.
[Graphical view]
PROSITEiPS51526. RFX_DBD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3ZCQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAVPASPA GGRGLHRGII QWLVDNFCIC EGFSVPRCLM YEIYVETCGQ
60 70 80 90 100
SAQNQVNPAT FGKLVRLVFP DLGTRRLGTR GSARYHYDGI YIKKSSFFYA
110 120 130 140 150
HYCYLLGKKS CHSGDLVAFG KSPDFNNVLQ QEETCESHSP IKTDPMGSPV
160 170 180 190 200
SPFRRCPFWE QELANKYSCK LVVFLADEYC NYCRDILQYV RNQELEKVGS
210 220 230 240 250
LVSSAVKTQQ QNSVFLLGIP XVRQLFGCYD MQLYKGLEDT LLPDFLEDVS
260 270 280 290 300
IQYLKSVRLF SKRFKLWLLG ALEGFPAILQ ISKLKEVTGF VKRLRRKTYL
310 320 330 340 350
SNMAKTMKMV LKNSRRVGLL KSDLRAIIRE GTLDISKKVL EGDSGHEEEP
360 370 380 390 400
ESHTEMKCLG CLISLLETST DLAELLNCVS SNLQALVFQP SKSKEEFIKL
410 420 430 440 450
AASFQLKWNF LLTAVSKAMT LSHRDSFGAW HLFHLLLLEY VIHILESCME
460 470 480 490 500
EEEEEEDLGS LQDLLSDDQF LTQPDQALFH SLDSLPASEC ASRNVESPQV
510 520 530 540 550
TLKHMSQSCS PMGVSSMVLQ VLGFLVDTAT GNKLIQVLLE DKATESAVKL
560 570 580 590
SLPVGQEALI TLSNGQRFVI HISDVPQSSE NTYCRKSDST MPGGLLE
Length:597
Mass (Da):66,999
Last modified:April 3, 2013 - v2
Checksum:i4BA7F02AAD5EF46B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06059967 Genomic DNA. No translation available.
AABR06059968 Genomic DNA. No translation available.
AABR06059969 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000047654; ENSRNOP00000043410; ENSRNOG00000032910.
UCSCiRGD:1560724. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06059967 Genomic DNA. No translation available.
AABR06059968 Genomic DNA. No translation available.
AABR06059969 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000047654; ENSRNOP00000043410; ENSRNOG00000032910.
UCSCiRGD:1560724. rat.

Organism-specific databases

RGDi1560724. Rfx8.

Phylogenomic databases

GeneTreeiENSGT00550000074532.
InParanoidiD3ZCQ8.
OMAiDNFCICE.
OrthoDBiEOG74BJRM.
TreeFamiTF342109.

Miscellaneous databases

NextBioi35566507.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR003150. DNA-bd_RFX.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF02257. RFX_DNA_binding. 1 hit.
[Graphical view]
PROSITEiPS51526. RFX_DBD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3ZCQ8_RAT
AccessioniPrimary (citable) accession number: D3ZCQ8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: April 1, 2015
This is version 34 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.