Olr754

Functionⁱ

GO - Molecular functionⁱ

G-protein coupled receptor activity Source: UniProtKB-KW
olfactory receptor activity Source: InterPro
transmembrane signaling receptor activity Source: GO_Central

GO - Biological processⁱ

detection of chemical stimulus involved in sensory perception Source: GO_Central
G-protein coupled receptor signaling pathway Source: GO_Central

Keywordsⁱ

Molecular function	G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological process	OlfactionUniRule annotationSAAS annotation, Sensory transduction

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Olfactory receptorUniRule annotation
Gene namesⁱ	Name:Olr754Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 3

Organism-specific databases

Rat genome database More...RGDⁱ	1333545. Olr754.

RGDⁱ

1333545. Olr754.

Subcellular locationⁱ

Cell membrane
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU363047
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00521146
; Multi-pass membrane protein
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU363047
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00521146

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	25 – 51	HelicalUniRule annotationAdd BLAST	27
Transmembraneⁱ	58 – 78	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	98 – 120	HelicalUniRule annotationAdd BLAST	23
Transmembraneⁱ	141 – 164	HelicalUniRule annotationAdd BLAST	24
Transmembraneⁱ	205 – 225	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	237 – 260	HelicalUniRule annotationAdd BLAST	24
Transmembraneⁱ	272 – 289	HelicalUniRule annotationAdd BLAST	18

GO - Cellular componentⁱ

integral component of membrane Source: GO_Central
plasma membrane Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cell membraneUniRule annotationSAAS annotation, Membrane

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	D3ZBR6.
PRIDEⁱ	D3ZBR6.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000043230.

STRINGⁱ

10116.ENSRNOP00000043230.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	D3ZBR6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	41 – 287	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		247

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118815.
InParanoidⁱ	D3ZBR6.
KEGG Orthology (KO) More...KOⁱ	K04257.
OMAⁱ	LCTTREL.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DM8.
PhylomeDBⁱ	D3ZBR6.
TreeFamⁱ	TF336512.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt.
PRINTSⁱ	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZBR6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEDSNHTGVS QFIFQGLCTT RELEIFLLLP FSTLYLMTIV GNLFVVILII 
        60         70         80         90        100
IDHHLHSPMY FLLANLSFVD FCLSSVNTPK LAIDLLKENK TISFGGCMSQ 
       110        120        130        140        150
ILCVHFFGGS EMVLLVTMAY DRCVAICRPL HYSTIMDRQK CIWLVVISWI 
       160        170        180        190        200
IGFVHAISQI LLILDLPFCG PRVIDSFFCD IPLVMKLACV NTDTLEILIN 
       210        220        230        240        250
ADSGILATTC FILLLISYTY ILLTVKLHSK DGSSKALSTC TSHIIVVVLF 
       260        270        280        290        300
FGPIIFIYLW PVNITWVDKF LAVFYTVITP FLNPAIYTLR NKDIKNAIRK 

LINHM

Length:305

Mass (Da):34,502

Last modified:April 20, 2010 - v1

Checksum:ⁱ2EA957CA06DDB551

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC121203 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001000368.1. NM_001000368.1.
UniGeneⁱ	Rn.142769.

Genome annotation databases

Ensemblⁱ	ENSRNOT00000047138; ENSRNOP00000043230; ENSRNOG00000050411.
GeneIDⁱ	296005.
KEGGⁱ	rno:296005.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC121203 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001000368.1. NM_001000368.1.
UniGeneⁱ	Rn.142769.

3D structure databases

ProteinModelPortalⁱ	D3ZBR6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000043230.

STRINGⁱ

10116.ENSRNOP00000043230.

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

Proteomic databases

PaxDbⁱ	D3ZBR6.
PRIDEⁱ	D3ZBR6.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000047138; ENSRNOP00000043230; ENSRNOG00000050411.
GeneIDⁱ	296005.
KEGGⁱ	rno:296005.

Organism-specific databases

CTDⁱ	296005.
Rat genome database More...RGDⁱ	1333545. Olr754.

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118815.
InParanoidⁱ	D3ZBR6.
KEGG Orthology (KO) More...KOⁱ	K04257.
OMAⁱ	LCTTREL.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0DM8.
PhylomeDBⁱ	D3ZBR6.
TreeFamⁱ	TF336512.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt.
PRINTSⁱ	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZBR6_RAT
Accessionⁱ	D3ZBR6Primary (citable) accession number: D3ZBR6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	June 7, 2017
	This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZBR6 (D3ZBR6_RAT)

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Olfactory receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ