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D3Z9J1

- D3Z9J1_RAT

UniProt

D3Z9J1 - D3Z9J1_RAT

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Protein
Submitted name: Dickkopf homolog 1 (Xenopus laevis) (Predicted)
Gene
Dkk1, DKK1, Dkk1_predicted, LOC100912050, rCG_48380
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. multicellular organismal development Source: InterPro
  2. negative regulation of Wnt signaling pathway Source: InterPro
  3. negative regulation of ossification Source: RGD
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_205336. negative regulation of TCF-dependent signaling by WNT ligand antagonists.
REACT_212065. TCF dependent signaling in response to WNT.

Names & Taxonomyi

Protein namesi
Submitted name:
Dickkopf homolog 1 (Xenopus laevis) (Predicted)Imported
Submitted name:
Dickkopf-like protein 1Imported
Submitted name:
Protein Dkk1Imported
Submitted name:
Protein LOC100912050Imported
Gene namesi
Name:Dkk1Imported
Synonyms:DKK1Imported, Dkk1_predictedImported, LOC100912050Imported
ORF Names:rCG_48380Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 1

Organism-specific databases

RGDi1307313. Dkk1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: RGD
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000007000.
KOiK02165.
OMAiGQEGSVC.
OrthoDBiEOG7K3TMT.
TreeFamiTF330916.

Family and domain databases

InterProiIPR006796. Dickkopf_N.
[Graphical view]
PfamiPF04706. Dickkopf_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z9J1-1 [UniParc]FASTAAdd to Basket

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MTVVRAVAAV RFLVVLSTMA LCSLPPLGVS ATLNSVLINS NAIKNLPPPL    50
GGAGGQPGSA VSVAPGVLYE GGNKYQTLDN YQPYPCAEDE ECGTDEYCSS 100
PSRGAAGVGG VQICLACRKR RKRCMRHAMC CPGNYCKNGI CMPSDHSHLP 150
RGEIEEGIIE NLGNDHGAGD GYPRRTTLTS KIYHTKGQEG SVCLRSSDCA 200
TGLCCARHFW SKICKPVLKE GQVCTKHRRK GSHGLEIFQR CYCGEGLACR 250
IQKDHHQTSN SSRLHTCQRH 270
Length:270
Mass (Da):29,149
Last modified:April 20, 2010 - v1
Checksum:iDED5D89186DD993F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06010531 Genomic DNA. No translation available.
AABR06010532 Genomic DNA. No translation available.
AABR06010533 Genomic DNA. No translation available.
JN966752 mRNA. Translation: AFI61655.1.
CH473953 Genomic DNA. Translation: EDM13121.1.
RefSeqiNP_001099820.1. NM_001106350.1.
XP_003749137.1. XM_003749089.2.
UniGeneiRn.214343.

Genome annotation databases

EnsembliENSRNOT00000015771; ENSRNOP00000015771; ENSRNOG00000011692.
ENSRNOT00000074393; ENSRNOP00000064286; ENSRNOG00000048688.
GeneIDi100912050.
293897.
KEGGirno:100912050.
rno:293897.
UCSCiRGD:1307313. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06010531 Genomic DNA. No translation available.
AABR06010532 Genomic DNA. No translation available.
AABR06010533 Genomic DNA. No translation available.
JN966752 mRNA. Translation: AFI61655.1 .
CH473953 Genomic DNA. Translation: EDM13121.1 .
RefSeqi NP_001099820.1. NM_001106350.1.
XP_003749137.1. XM_003749089.2.
UniGenei Rn.214343.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000015771 ; ENSRNOP00000015771 ; ENSRNOG00000011692 .
ENSRNOT00000074393 ; ENSRNOP00000064286 ; ENSRNOG00000048688 .
GeneIDi 100912050.
293897.
KEGGi rno:100912050.
rno:293897.
UCSCi RGD:1307313. rat.

Organism-specific databases

CTDi 22943.
RGDi 1307313. Dkk1.

Phylogenomic databases

GeneTreei ENSGT00390000007000.
KOi K02165.
OMAi GQEGSVC.
OrthoDBi EOG7K3TMT.
TreeFami TF330916.

Enzyme and pathway databases

Reactomei REACT_205336. negative regulation of TCF-dependent signaling by WNT ligand antagonists.
REACT_212065. TCF dependent signaling in response to WNT.

Miscellaneous databases

NextBioi 637227.
PROi D3Z9J1.

Family and domain databases

InterProi IPR006796. Dickkopf_N.
[Graphical view ]
Pfami PF04706. Dickkopf_N. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.
  5. "Molecular cloning and bioinformatic analysis of DKK1."
    Hu L., Jiang G., Yang J., Liu S.
    Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  6. Ensembl
    Submitted (FEB-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD3Z9J1_RAT
AccessioniPrimary (citable) accession number: D3Z9J1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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