D3Z9J1 (D3Z9J1_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dickkopf homolog 1 (Xenopus laevis) (Predicted) EMBL EDM13121.1

Submitted name:
Dickkopf-like protein 1 EMBL AFI61655.1
Submitted name:
Protein Dkk1 Ensembl ENSRNOP00000015771
Submitted name:
Protein LOC100912050 Ensembl ENSRNOP00000064286

Gene names

Name:	Dkk1 Ensembl ENSRNOP00000015771 RGD 1307313
Synonyms:	DKK1 EMBL AFI61655.1, Dkk1_predicted EMBL EDM13121.1, LOC100912050 Ensembl ENSRNOP00000064286
ORF Names:	rCG_48380 EMBL EDM13121.1

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000015771

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	multicellular organismal development Inferred from electronic annotation. Source: InterPro negative regulation of Wnt receptor signaling pathway Inferred from electronic annotation. Source: InterPro negative regulation of ossification Inferred from mutant phenotype PubMed 21773994. Source: RGD
Cellular_component	extracellular space Inferred from direct assay PubMed 22009597. Source: RGD
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3Z9J1 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: DED5D89186DD993F	FASTA	270	29,149
	10 20 30 40 50 60 MTVVRAVAAV RFLVVLSTMA LCSLPPLGVS ATLNSVLINS NAIKNLPPPL GGAGGQPGSA 70 80 90 100 110 120 VSVAPGVLYE GGNKYQTLDN YQPYPCAEDE ECGTDEYCSS PSRGAAGVGG VQICLACRKR 130 140 150 160 170 180 RKRCMRHAMC CPGNYCKNGI CMPSDHSHLP RGEIEEGIIE NLGNDHGAGD GYPRRTTLTS 190 200 210 220 230 240 KIYHTKGQEG SVCLRSSDCA TGLCCARHFW SKICKPVLKE GQVCTKHRRK GSHGLEIFQR 250 260 270 CYCGEGLACR IQKDHHQTSN SSRLHTCQRH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000015771 Ensembl ENSRNOP00000064286.
[2]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDM13121.1.
[3]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDM13121.1.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000015771.
[5]	"Molecular cloning and bioinformatic analysis of DKK1." Hu L., Jiang G., Yang J., Liu S. Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[6]	Ensembl Submitted (FEB-2013) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000064286.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06010531 Genomic DNA. No translation available. AABR06010532 Genomic DNA. No translation available. AABR06010533 Genomic DNA. No translation available. JN966752 mRNA. Translation: AFI61655.1. CH473953 Genomic DNA. Translation: EDM13121.1.
IPI	IPI00361250.
RefSeq	NP_001099820.1. NM_001106350.1. XP_003749137.1. XM_003749089.1.
UniGene	Rn.214343.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000015771; ENSRNOP00000015771; ENSRNOG00000011692. ENSRNOT00000074393; ENSRNOP00000064286; ENSRNOG00000048688.
GeneID	100912050. 293897.
KEGG	rno:100912050. rno:293897.
UCSC	RGD:1307313. rat.
Organism-specific databases
CTD	22943.
RGD	1307313. Dkk1.
Phylogenomic databases
GeneTree	ENSGT00390000007000.
KO	K02165.
OMA	GSVCLRS.
OrthoDB	EOG4DFPP7.
Family and domain databases
InterPro	IPR006796. Dickkopf_N. [Graphical view]
Pfam	PF04706. Dickkopf_N. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	637227.

Entry information

Entry name

D3Z9J1_RAT

Accession

Primary (citable) accession number: D3Z9J1

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	April 3, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)