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Protein
Submitted name:

Solute carrier family 12 member 8

Gene

Slc12a8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 12 member 8Imported
Gene namesi
Name:Slc12a8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2443672 Slc12a8

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 59HelicalSequence analysisAdd BLAST24
Transmembranei71 – 92HelicalSequence analysisAdd BLAST22
Transmembranei98 – 115HelicalSequence analysisAdd BLAST18
Transmembranei122 – 141HelicalSequence analysisAdd BLAST20
Transmembranei153 – 172HelicalSequence analysisAdd BLAST20
Transmembranei184 – 204HelicalSequence analysisAdd BLAST21
Transmembranei232 – 253HelicalSequence analysisAdd BLAST22
Transmembranei265 – 286HelicalSequence analysisAdd BLAST22
Transmembranei306 – 330HelicalSequence analysisAdd BLAST25
Transmembranei342 – 371HelicalSequence analysisAdd BLAST30

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000035506
ExpressionAtlasiD3Z6X1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD3Z6X1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 350AA_permeaseInterPro annotationAdd BLAST307

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2083 Eukaryota
COG0531 LUCA
GeneTreeiENSGT00760000119053
HOGENOMiHOG000045198

Family and domain databases

InterProiView protein in InterPro
IPR004841 AA-permease/SLC12A_dom
PfamiView protein in Pfam
PF00324 AA_permease, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z6X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQRSPQELF HEAAQQGILA QPQPWWKIQL FMWEPVLFGT WDGVFTSCMI
60 70 80 90 100
NIFGVVLFLR TGWLVGNTGV LLGLLLVSFV VLVALITVLS GIGVAEHGGI
110 120 130 140 150
SSGGVYSMIS SVLGGQMGGT VGLLYVFGQC VAGAMYITGF AESISDLLGL
160 170 180 190 200
GDIWAVRGIS VAVLLALLGI NLAGVKWIIR LQLLLLLLLA VSTLDFVVGS
210 220 230 240 250
FTHLDPEHGF IGYSPELLQS NILPEYSPGE SFFTVFGVFF PAATGVMAGF
260 270 280 290 300
NMGGDLRDPA DSVPLGSLAA VGVSWFLYII FAFLLGAVCT REALRSDFLI
310 320 330 340 350
AEKVSLVGFL FLLGLYISSL ASCMGGLYGA PRILQCIAQD KVIPALAFLA
360 370 380 390 400
NGVNVLAPVV TINFMLTYIM VDYSYFALSM AHCGLAPSPE PVPRQGPDTL
410 420 430 440 450
HCSEHLLQDR APSYGSDVPA RSLSEGTLLE FTKDMDQFLQ PIEELESRQL
460 470 480 490 500
GSREGNNPKN QKRKGKKGAK QTLQDSFLLD PGSPLSFPTR TSERLSVAFC
510 520 530 540 550
GEQESYQKQQ TSRSESHDHL VPDLRNQPRV NREDFFLKCR LQEQEIQRRP
560 570 580
SVFYACMCNP WVSLLGEPEV RPGANHLGAI TSQG
Length:584
Mass (Da):63,487
Last modified:April 20, 2010 - v1
Checksum:iA7ED3E6A11927034
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121570 Genomic DNA No translation available.
AC127412 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000122427; ENSMUSP00000113164; ENSMUSG00000035506

Similar proteinsi

Entry informationi

Entry nameiD3Z6X1_MOUSE
AccessioniPrimary (citable) accession number: D3Z6X1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: March 28, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health