Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Solute carrier family 12 member 8

Gene

Slc12a8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 12 member 8Imported
Gene namesi
Name:Slc12a8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2443672. Slc12a8.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 59HelicalSequence analysisAdd BLAST24
Transmembranei71 – 92HelicalSequence analysisAdd BLAST22
Transmembranei98 – 115HelicalSequence analysisAdd BLAST18
Transmembranei122 – 141HelicalSequence analysisAdd BLAST20
Transmembranei153 – 172HelicalSequence analysisAdd BLAST20
Transmembranei184 – 204HelicalSequence analysisAdd BLAST21
Transmembranei232 – 253HelicalSequence analysisAdd BLAST22
Transmembranei265 – 286HelicalSequence analysisAdd BLAST22
Transmembranei306 – 330HelicalSequence analysisAdd BLAST25
Transmembranei342 – 371HelicalSequence analysisAdd BLAST30

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiD3Z6X1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000035506.
ExpressionAtlasiD3Z6X1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062337.

Structurei

3D structure databases

ProteinModelPortaliD3Z6X1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 350AA_permeaseInterPro annotationAdd BLAST307

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2083. Eukaryota.
COG0531. LUCA.
GeneTreeiENSGT00760000119053.
HOGENOMiHOG000045198.

Family and domain databases

InterProiIPR004841. AA-permease/SLC12A_dom.
[Graphical view]
PfamiPF00324. AA_permease. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z6X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQRSPQELF HEAAQQGILA QPQPWWKIQL FMWEPVLFGT WDGVFTSCMI
60 70 80 90 100
NIFGVVLFLR TGWLVGNTGV LLGLLLVSFV VLVALITVLS GIGVAEHGGI
110 120 130 140 150
SSGGVYSMIS SVLGGQMGGT VGLLYVFGQC VAGAMYITGF AESISDLLGL
160 170 180 190 200
GDIWAVRGIS VAVLLALLGI NLAGVKWIIR LQLLLLLLLA VSTLDFVVGS
210 220 230 240 250
FTHLDPEHGF IGYSPELLQS NILPEYSPGE SFFTVFGVFF PAATGVMAGF
260 270 280 290 300
NMGGDLRDPA DSVPLGSLAA VGVSWFLYII FAFLLGAVCT REALRSDFLI
310 320 330 340 350
AEKVSLVGFL FLLGLYISSL ASCMGGLYGA PRILQCIAQD KVIPALAFLA
360 370 380 390 400
NGVNVLAPVV TINFMLTYIM VDYSYFALSM AHCGLAPSPE PVPRQGPDTL
410 420 430 440 450
HCSEHLLQDR APSYGSDVPA RSLSEGTLLE FTKDMDQFLQ PIEELESRQL
460 470 480 490 500
GSREGNNPKN QKRKGKKGAK QTLQDSFLLD PGSPLSFPTR TSERLSVAFC
510 520 530 540 550
GEQESYQKQQ TSRSESHDHL VPDLRNQPRV NREDFFLKCR LQEQEIQRRP
560 570 580
SVFYACMCNP WVSLLGEPEV RPGANHLGAI TSQG
Length:584
Mass (Da):63,487
Last modified:April 20, 2010 - v1
Checksum:iA7ED3E6A11927034
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121570 Genomic DNA. No translation available.
AC127412 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000122427; ENSMUSP00000113164; ENSMUSG00000035506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121570 Genomic DNA. No translation available.
AC127412 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3Z6X1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062337.

Proteomic databases

PaxDbiD3Z6X1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000122427; ENSMUSP00000113164; ENSMUSG00000035506.

Organism-specific databases

MGIiMGI:2443672. Slc12a8.

Phylogenomic databases

eggNOGiKOG2083. Eukaryota.
COG0531. LUCA.
GeneTreeiENSGT00760000119053.
HOGENOMiHOG000045198.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000035506.
ExpressionAtlasiD3Z6X1. baseline and differential.

Family and domain databases

InterProiIPR004841. AA-permease/SLC12A_dom.
[Graphical view]
PfamiPF00324. AA_permease. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z6X1_MOUSE
AccessioniPrimary (citable) accession number: D3Z6X1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 2, 2016
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.