Forkhead box protein P1

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• chromatin binding Source: Ensembl
• protein heterodimerization activity Source: Ensembl
• protein homodimerization activity Source: Ensembl
• RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl
• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Source: Ensembl

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• cardiac muscle cell differentiation Source: Ensembl
• cardiovascular system development Source: Ensembl
• immunoglobulin V(D)J recombination Source: Ensembl
• interleukin-21 secretion Source: Ensembl
• in utero embryonic development Source: Ensembl
• lung secretory cell differentiation Source: Ensembl
• motor neuron axon guidance Source: Ensembl
• negative regulation of lung goblet cell differentiation Source: Ensembl
• negative regulation of transcription by RNA polymerase II Source: Ensembl
• positive regulation of cardiac muscle cell differentiation Source: Ensembl
• positive regulation of epithelial cell proliferation Source: Ensembl
• positive regulation of immunoglobulin production Source: Ensembl
• positive regulation of mesenchymal cell proliferation Source: Ensembl
• positive regulation of transcription by RNA polymerase II Source: Ensembl
• pre-B cell differentiation Source: Ensembl
• regulation of cardiac muscle cell proliferation Source: Ensembl
• sarcomere organization Source: Ensembl
• skeletal muscle tissue development Source: Ensembl
• smooth muscle tissue development Source: Ensembl
• T follicular helper cell differentiation Source: Ensembl
• transcription, DNA-templated Source: UniProtKB-KW
• ventral spinal cord development Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• protein heterodimerization activity Source: Ensembl
• protein homodimerization activity Source: Ensembl

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Coiled coil

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MMQESGSETK SNGSAIQNGS SGGNHLLECG ALRDTRSNGE APAVDLGAAD 
        60         70         80         90        100
LAHVQQQQQQ ALQVARQLLL QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ 
       110        120        130        140        150
QQQQQQQVSG LKSPKRNDKQ PALQVPVSVA MMTPQVITPQ QMQQILQQQV 
       160        170        180        190        200
LSPQQLQVLL QQQQALMLQQ QLQEFYKKQQ EQLQLQLLQQ QHAGKQPKEQ 
       210        220        230        240        250
QQVATQQLAF QQQLLQMQQL QQQHLLSLQR QGLLTIQPGQ PALPLQPLAQ 
       260        270        280        290        300
GMIPTELQQL WKEVTSAHTA EETTSSNHSS LDLTSTCVSS SAPSKSSLIM 
       310        320        330        340        350
NPHASTNGQL SVHTPKRESL SHEEHPHSHP LYGHGVCKWP GCEAVCDDFP 
       360        370        380        390        400
AFLKHLNSEH ALDDRSTAQC RVQMQVVQQL ELQLAKDKER LQAMMTHLHV 
       410        420        430        440        450
KSTEPKAAPQ PLNLVSSVTL SKSASEASPQ SLPHTPTTPT APLTPVTQGP 
       460        470        480        490        500
SVITTTSMHT VGPIRRRYSD KYNVPISSAD IAQNQEFYKN AEVRPPFTYA 
       510        520        530        540        550
SLIRQAILES PEKQLTLNEI YNWFTRMFAY FRRNAATWKN AVRHNLSLHK 
       560        570        580        590        600
CFVRVENVKG AVWTVDEVEF QKRRPQKISG NPSLIKNMQS SHAYCTPLNA 
       610        620        630        640        650
ALQASMAENS IPLYTTASMG NPTLGSLASA IREELNGAME HTNSNESDSS 
       660        670        680        690        700
PGRSPMQAVH PIHVKEEPLD PEEAEGPLSL VTTANHSPDF DHDRDYEDEP 

VNEDME                                                 

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ