D3Z6I1 (D3Z6I1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Mmp27 Ensembl ENSMUSP00000113231

Gene names

Name:

Mmp27 Ensembl ENSMUSP00000113231 MGI 3039232

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000113231

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 4 hemopexin-like domains. SAAS SAAS016293
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000113231

Ontologies

Keywords
Domain	Repeat SAAS SAAS016293
Ligand	Calcium SAAS SAAS016293 Metal-binding SAAS SAAS016293 Zinc SAAS SAAS016293
Molecular function	Hydrolase Metalloprotease SAAS SAAS016293 Protease
PTM	Disulfide bond SAAS SAAS016293
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	232	1	By similarity PIRSR PIRSR001191-1

Sequences

	Sequence		Length	Mass (Da)
	D3Z6I1 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: D8FDC46E7AA45897	FASTA	525	59,630
	10 20 30 40 50 60 MPYKQKQALT EETGMKCLLS LMVNFITLSA AFPPDRKDKN EENNQLAQAY LNQFYSLEIE 70 80 90 100 110 120 GSHFVQSKNR SLFDGKLREM QAFFGLTVTG KLDSDTLAIM KVPRCGVPDV GQYGYTLPGW 130 140 150 160 170 180 RKYSLTYRIM NYTPDMTPAD VDEAIQKALQ VWSKVTPLTF TRISKGVADI MIAFRTGVHG 190 200 210 220 230 240 WCPRHFDGPL GVLGHAFPPG LGLGGDTHFD EDETWIAKDG EGFNLFLVAA HEFGHSLGLS 250 260 270 280 290 300 HSNDQTALMF PNYISLDPSK YPLSQDDIDG IQSIYGSPPK VTTKPSGNSE PHACDPTLTF 310 320 330 340 350 360 DAITTFRREV MFFKGRHLWR VYSDIAGAEF EFIDSFWPSL PADLQAAYES PRDELLVFKD 370 380 390 400 410 420 ENFWVIRGYS VLPGYPKSIH TLGFPRRVKK IDAAVCDHDT RKTFFFVGIW CWRYDEMAQA 430 440 450 460 470 480 MDRGFPQRII KCFPGIRLRV DAVFQHNGFL YFFHGSRQFE YDMKAKNITQ VIKTNSWFLC 490 500 510 520 NEPLNASFNV SVKGKANSIG TVILHHKRLS LLTFSIVHVL TKTYN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000113231.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000113231.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC115689 Genomic DNA. No translation available.
IPI	IPI00895010.
3D structure databases
ProteinModelPortal	D3Z6I1.
SMR	D3Z6I1. Positions 46-480.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000120900; ENSMUSP00000113231; ENSMUSG00000070323.
UCSC	uc009oct.1. mouse.
Organism-specific databases
MGI	MGI:3039232. Mmp27.
Phylogenomic databases
GeneTree	ENSGT00630000089491.
HOGENOM	HOG000217927.
Gene expression databases
ArrayExpress	D3Z6I1.
Bgee	D3Z6I1.
Family and domain databases
Gene3D	2.110.10.10. 1 hit. 3.40.390.10. 1 hit.
InterPro	IPR000585. Hemopexin-like_dom. IPR018487. Hemopexin-like_repeat. IPR018486. Hemopexin_CS. IPR024079. MetalloPept_cat_dom. IPR001818. Pept_M10_metallopeptidase. IPR021190. Pept_M10A. IPR016293. Pept_M10A_Metazoans. IPR021158. Pept_M10A_Zn_BS. IPR006026. Peptidase_Metallo. IPR002477. Peptidoglycan-bd-like. [Graphical view]
Pfam	PF00045. Hemopexin. 3 hits. PF00413. Peptidase_M10. 1 hit. PF01471. PG_binding_1. 1 hit. [Graphical view]
PIRSF	PIRSF001191. Peptidase_M10A_matrix. 1 hit.
PRINTS	PR00138. MATRIXIN.
SMART	SM00120. HX. 4 hits. SM00235. ZnMc. 1 hit. [Graphical view]
SUPFAM	SSF50923. Hemopexin. 1 hit. SSF47090. PGBD_like. 1 hit.
PROSITE	PS00546. CYSTEINE_SWITCH. 1 hit. PS00024. HEMOPEXIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35551464.
SOURCE	Search...

Entry information

Entry name

D3Z6I1_MOUSE

Accession

Primary (citable) accession number: D3Z6I1

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)