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Protein
Submitted name:

Serine/threonine-protein kinase D3

Gene

Prkd3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei510ATPUniRule annotation1
Active sitei604Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi487 – 495ATPUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase D3Imported
Gene namesi
Name:Prkd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1922542 Prkd3

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiD3Z6I0
PeptideAtlasiD3Z6I0
PRIDEiD3Z6I0

Expressioni

Gene expression databases

BgeeiENSMUSG00000024070
ExpressionAtlasiD3Z6I0 baseline and differential
GenevisibleiD3Z6I0 MM

Structurei

3D structure databases

ProteinModelPortaliD3Z6I0
SMRiD3Z6I0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 109Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini176 – 226Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini321 – 437PHInterPro annotationAdd BLAST117
Domaini481 – 737Protein kinaseInterPro annotationAdd BLAST257

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG4236 Eukaryota
ENOG410XQZ3 LUCA
GeneTreeiENSGT00910000144054
HOGENOMiHOG000015135

Family and domain databases

CDDicd00029 C1, 2 hits
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR020454 DAG/PE-bd
IPR011009 Kinase-like_dom_sf
IPR002219 PE/DAG-bd
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR015727 Protein_Kinase_C_mu-related
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR22968 PTHR22968, 1 hit
PfamiView protein in Pfam
PF00130 C1_1, 2 hits
PF00169 PH, 1 hit
PF00069 Pkinase, 1 hit
PIRSFiPIRSF000552 PKC_mu_nu_D2, 1 hit
PRINTSiPR00008 DAGPEDOMAIN
SMARTiView protein in SMART
SM00109 C1, 2 hits
SM00233 PH, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS00479 ZF_DAG_PE_1, 2 hits
PS50081 ZF_DAG_PE_2, 2 hits

Sequencei

Sequence statusi: Complete.

D3Z6I0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPECGFFGM YDKILLFRHD MNSENILQLI TSADEIHEGD LVEVVLSALA
60 70 80 90 100
TVEDFQIRPH ALYVHSYKAP TFCDYCGEML WGLVRQGLKC EGCGLNYHKR
110 120 130 140 150
CAFKIPNNCS GVRKRRLSNV SLPGPGLSVP RPLQPECVPL LSEESHTHQE
160 170 180 190 200
PSKRIPSWSG RPIWMEKMVM CRVKVPHTFA VHSYGRPTIC QYCKRLLKGL
210 220 230 240 250
FRQGMQCKDC KFNCHKRCAS KVPRDCLGEV TFNGEPCSVG TDADMPMDID
260 270 280 290 300
SSDVNSDGSR GLDDSEEPSP PEDKMFFLDP TDLDVERDEE TVKTISPSTS
310 320 330 340 350
NNIPLMRVVQ SIKHTKRRSS TVVKEGWMVH YTSRDNLRKR HYWRLDSKCL
360 370 380 390 400
TLFQNESGSK YYKEIPLSEI LRVSSPQDFT SISQGSNPHC FEIITDTVVY
410 420 430 440 450
FVGENNGSSS HNPVLAATGV GLDVAQSWEK AIRQALMPVT PQASVCTSPG
460 470 480 490 500
QGKDHKDLAT SISVSNCQVQ ENVDISSVYQ IFADEVLGSG QFGIVYGGKH
510 520 530 540 550
RKTGRDVAIK VIDKMRFPTK QESQLRNEVA ILQNLHHPGI VNLECMFETP
560 570 580 590 600
ERVFVVMEKL HGDMLEMILS SEKSRLPERI TKFMVTQILV ALRNLHFKNI
610 620 630 640 650
VHCDLKPENV LLASAEPFPQ VKLCDFGFAR IIGEKSFRRS VVGTPAYLAP
660 670 680 690 700
EVLRSKGYNR SLDMWSVGVI VYVSLSGTFP FNEDEDINDQ IQNAAFMYPP
710 720 730 740 750
NPWREISSEA IDLINNLLQV KMRKRYSVDK SLSHPWLQDY QTWLDLREFE
760 770 780 790
TRIGERYITH ESDDARWEIH AYTHNLEYPK HFIMAPNPDD MEEDP
Length:795
Mass (Da):90,450
Last modified:April 20, 2010 - v1
Checksum:iDD53C2340C11658C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151293 Genomic DNA No translation available.
AC154274 Genomic DNA No translation available.
RefSeqiNP_001164476.1, NM_001171005.1
UniGeneiMm.252776

Genome annotation databases

EnsembliENSMUST00000118768; ENSMUSP00000113232; ENSMUSG00000024070
GeneIDi75292
UCSCiuc008dpq.2 mouse

Similar proteinsi

Entry informationi

Entry nameiD3Z6I0_MOUSE
AccessioniPrimary (citable) accession number: D3Z6I0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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