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D3Z6I0

- D3Z6I0_MOUSE

UniProt

D3Z6I0 - D3Z6I0_MOUSE

Protein
Submitted name:

Serine/threonine-protein kinase D3

Gene

Prkd3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.SAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. protein kinase C activity Source: InterPro

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Metal-binding, Nucleotide-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Serine/threonine-protein kinase D3Imported
    Gene namesi
    Name:Prkd3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1922542. Prkd3.

    PTM / Processingi

    Proteomic databases

    PRIDEiD3Z6I0.

    Expressioni

    Gene expression databases

    ArrayExpressiD3Z6I0.
    BgeeiD3Z6I0.

    Structurei

    3D structure databases

    ProteinModelPortaliD3Z6I0.
    SMRiD3Z6I0. Positions 60-109, 177-226, 319-437, 450-739.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PH domain.UniRule annotation
    Contains PH domain.SAAS annotation
    Contains protein kinase domain.SAAS annotation

    Keywords - Domaini

    Zinc-fingerSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117523.
    HOGENOMiHOG000015135.
    KOiK06070.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR020454. DAG/PE-bd.
    IPR011009. Kinase-like_dom.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR015727. Protein_Kinase_C_mu-related.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PANTHERiPTHR22968. PTHR22968. 1 hit.
    PfamiPF00130. C1_1. 2 hits.
    PF00169. PH. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000552. PKC_mu_nu_D2. 1 hit.
    PRINTSiPR00008. DAGPEDOMAIN.
    SMARTiSM00109. C1. 2 hits.
    SM00233. PH. 1 hit.
    SM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50003. PH_DOMAIN. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    PS00479. ZF_DAG_PE_1. 2 hits.
    PS50081. ZF_DAG_PE_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3Z6I0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFPECGFFGM YDKILLFRHD MNSENILQLI TSADEIHEGD LVEVVLSALA    50
    TVEDFQIRPH ALYVHSYKAP TFCDYCGEML WGLVRQGLKC EGCGLNYHKR 100
    CAFKIPNNCS GVRKRRLSNV SLPGPGLSVP RPLQPECVPL LSEESHTHQE 150
    PSKRIPSWSG RPIWMEKMVM CRVKVPHTFA VHSYGRPTIC QYCKRLLKGL 200
    FRQGMQCKDC KFNCHKRCAS KVPRDCLGEV TFNGEPCSVG TDADMPMDID 250
    SSDVNSDGSR GLDDSEEPSP PEDKMFFLDP TDLDVERDEE TVKTISPSTS 300
    NNIPLMRVVQ SIKHTKRRSS TVVKEGWMVH YTSRDNLRKR HYWRLDSKCL 350
    TLFQNESGSK YYKEIPLSEI LRVSSPQDFT SISQGSNPHC FEIITDTVVY 400
    FVGENNGSSS HNPVLAATGV GLDVAQSWEK AIRQALMPVT PQASVCTSPG 450
    QGKDHKDLAT SISVSNCQVQ ENVDISSVYQ IFADEVLGSG QFGIVYGGKH 500
    RKTGRDVAIK VIDKMRFPTK QESQLRNEVA ILQNLHHPGI VNLECMFETP 550
    ERVFVVMEKL HGDMLEMILS SEKSRLPERI TKFMVTQILV ALRNLHFKNI 600
    VHCDLKPENV LLASAEPFPQ VKLCDFGFAR IIGEKSFRRS VVGTPAYLAP 650
    EVLRSKGYNR SLDMWSVGVI VYVSLSGTFP FNEDEDINDQ IQNAAFMYPP 700
    NPWREISSEA IDLINNLLQV KMRKRYSVDK SLSHPWLQDY QTWLDLREFE 750
    TRIGERYITH ESDDARWEIH AYTHNLEYPK HFIMAPNPDD MEEDP 795
    Length:795
    Mass (Da):90,450
    Last modified:April 20, 2010 - v1
    Checksum:iDD53C2340C11658C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151293 Genomic DNA. No translation available.
    AC154274 Genomic DNA. No translation available.
    RefSeqiNP_001164476.1. NM_001171005.1.
    UniGeneiMm.252776.

    Genome annotation databases

    EnsembliENSMUST00000118768; ENSMUSP00000113232; ENSMUSG00000024070.
    GeneIDi75292.
    KEGGimmu:75292.
    UCSCiuc008dpq.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151293 Genomic DNA. No translation available.
    AC154274 Genomic DNA. No translation available.
    RefSeqi NP_001164476.1. NM_001171005.1.
    UniGenei Mm.252776.

    3D structure databases

    ProteinModelPortali D3Z6I0.
    SMRi D3Z6I0. Positions 60-109, 177-226, 319-437, 450-739.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D3Z6I0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000118768 ; ENSMUSP00000113232 ; ENSMUSG00000024070 .
    GeneIDi 75292.
    KEGGi mmu:75292.
    UCSCi uc008dpq.2. mouse.

    Organism-specific databases

    CTDi 23683.
    MGIi MGI:1922542. Prkd3.

    Phylogenomic databases

    GeneTreei ENSGT00750000117523.
    HOGENOMi HOG000015135.
    KOi K06070.

    Miscellaneous databases

    NextBioi 342658.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D3Z6I0.
    Bgeei D3Z6I0.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR020454. DAG/PE-bd.
    IPR011009. Kinase-like_dom.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR015727. Protein_Kinase_C_mu-related.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    PANTHERi PTHR22968. PTHR22968. 1 hit.
    Pfami PF00130. C1_1. 2 hits.
    PF00169. PH. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000552. PKC_mu_nu_D2. 1 hit.
    PRINTSi PR00008. DAGPEDOMAIN.
    SMARTi SM00109. C1. 2 hits.
    SM00233. PH. 1 hit.
    SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50003. PH_DOMAIN. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    PS00479. ZF_DAG_PE_1. 2 hits.
    PS50081. ZF_DAG_PE_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z6I0_MOUSE
    AccessioniPrimary (citable) accession number: D3Z6I0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3