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Protein
Submitted name:

Serine/threonine-protein kinase D3

Gene

Prkd3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei510ATPUniRule annotation1
Active sitei604Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi487 – 495ATPUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase D3Imported
Gene namesi
Name:Prkd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1922542. Prkd3.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiD3Z6I0.
PaxDbiD3Z6I0.
PeptideAtlasiD3Z6I0.
PRIDEiD3Z6I0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000024070.
ExpressionAtlasiD3Z6I0. baseline and differential.
GenevisibleiD3Z6I0. MM.

Structurei

3D structure databases

ProteinModelPortaliD3Z6I0.
SMRiD3Z6I0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 109Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini176 – 226Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini321 – 437PHInterPro annotationAdd BLAST117
Domaini481 – 737Protein kinaseInterPro annotationAdd BLAST257

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG4236. Eukaryota.
ENOG410XQZ3. LUCA.
GeneTreeiENSGT00840000129794.
HOGENOMiHOG000015135.

Family and domain databases

CDDicd00029. C1. 2 hits.
Gene3Di2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR020454. DAG/PE-bd.
IPR011009. Kinase-like_dom.
IPR002219. PE/DAG-bd.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR015727. Protein_Kinase_C_mu-related.
IPR008271. Ser/Thr_kinase_AS.
PANTHERiPTHR22968. PTHR22968. 1 hit.
PfamiView protein in Pfam
PF00130. C1_1. 2 hits.
PF00169. PH. 1 hit.
PF00069. Pkinase. 1 hit.
PIRSFiPIRSF000552. PKC_mu_nu_D2. 1 hit.
PRINTSiPR00008. DAGPEDOMAIN.
SMARTiView protein in SMART
SM00109. C1. 2 hits.
SM00233. PH. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50003. PH_DOMAIN. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS00479. ZF_DAG_PE_1. 2 hits.
PS50081. ZF_DAG_PE_2. 2 hits.

Sequencei

Sequence statusi: Complete.

D3Z6I0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPECGFFGM YDKILLFRHD MNSENILQLI TSADEIHEGD LVEVVLSALA
60 70 80 90 100
TVEDFQIRPH ALYVHSYKAP TFCDYCGEML WGLVRQGLKC EGCGLNYHKR
110 120 130 140 150
CAFKIPNNCS GVRKRRLSNV SLPGPGLSVP RPLQPECVPL LSEESHTHQE
160 170 180 190 200
PSKRIPSWSG RPIWMEKMVM CRVKVPHTFA VHSYGRPTIC QYCKRLLKGL
210 220 230 240 250
FRQGMQCKDC KFNCHKRCAS KVPRDCLGEV TFNGEPCSVG TDADMPMDID
260 270 280 290 300
SSDVNSDGSR GLDDSEEPSP PEDKMFFLDP TDLDVERDEE TVKTISPSTS
310 320 330 340 350
NNIPLMRVVQ SIKHTKRRSS TVVKEGWMVH YTSRDNLRKR HYWRLDSKCL
360 370 380 390 400
TLFQNESGSK YYKEIPLSEI LRVSSPQDFT SISQGSNPHC FEIITDTVVY
410 420 430 440 450
FVGENNGSSS HNPVLAATGV GLDVAQSWEK AIRQALMPVT PQASVCTSPG
460 470 480 490 500
QGKDHKDLAT SISVSNCQVQ ENVDISSVYQ IFADEVLGSG QFGIVYGGKH
510 520 530 540 550
RKTGRDVAIK VIDKMRFPTK QESQLRNEVA ILQNLHHPGI VNLECMFETP
560 570 580 590 600
ERVFVVMEKL HGDMLEMILS SEKSRLPERI TKFMVTQILV ALRNLHFKNI
610 620 630 640 650
VHCDLKPENV LLASAEPFPQ VKLCDFGFAR IIGEKSFRRS VVGTPAYLAP
660 670 680 690 700
EVLRSKGYNR SLDMWSVGVI VYVSLSGTFP FNEDEDINDQ IQNAAFMYPP
710 720 730 740 750
NPWREISSEA IDLINNLLQV KMRKRYSVDK SLSHPWLQDY QTWLDLREFE
760 770 780 790
TRIGERYITH ESDDARWEIH AYTHNLEYPK HFIMAPNPDD MEEDP
Length:795
Mass (Da):90,450
Last modified:April 20, 2010 - v1
Checksum:iDD53C2340C11658C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151293 Genomic DNA. No translation available.
AC154274 Genomic DNA. No translation available.
RefSeqiNP_001164476.1. NM_001171005.1.
UniGeneiMm.252776.

Genome annotation databases

EnsembliENSMUST00000118768; ENSMUSP00000113232; ENSMUSG00000024070.
GeneIDi75292.
UCSCiuc008dpq.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiD3Z6I0_MOUSE
AccessioniPrimary (citable) accession number: D3Z6I0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: August 30, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported