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Protein
Submitted name:

Sorbin and SH3 domain-containing protein 1

Gene

Sorbs1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-445355 Smooth Muscle Contraction

Names & Taxonomyi

Protein namesi
Submitted name:
Sorbin and SH3 domain-containing protein 1Imported
Gene namesi
Name:Sorbs1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:700014 Sorbs1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

PTM databases

iPTMnetiD3Z5J3

Expressioni

Gene expression databases

BgeeiENSMUSG00000025006
GenevisibleiD3Z5J3 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097066

Structurei

3D structure databases

ProteinModelPortaliD3Z5J3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini326 – 429SoHoInterPro annotationAdd BLAST104
Domaini697 – 756SH3InterPro annotationAdd BLAST60
Domaini771 – 832SH3InterPro annotationAdd BLAST62
Domaini877 – 938SH3InterPro annotationAdd BLAST62

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4225 Eukaryota
ENOG41110AD LUCA
GeneTreeiENSGT00760000119190
HOGENOMiHOG000294090
OMAiDYIDLPF
OrthoDBiEOG091G0172
TreeFamiTF320680

Family and domain databases

CDDicd11919 SH3_Sorbs1_1, 1 hit
cd11922 SH3_Sorbs1_2, 1 hit
cd11916 SH3_Sorbs1_3, 1 hit
InterProiView protein in InterPro
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR003127 SoHo_dom
IPR028506 Sorbin_SH3
IPR035606 SORBS1_SH3
IPR035610 SORBS1_SH3_1
IPR035611 SORBS1_SH3_2
PANTHERiPTHR45043 PTHR45043, 1 hit
PfamiView protein in Pfam
PF00018 SH3_1, 1 hit
PF07653 SH3_2, 1 hit
PF14604 SH3_9, 1 hit
PF02208 Sorb, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00326 SH3, 3 hits
SM00459 Sorb, 1 hit
SUPFAMiSSF50044 SSF50044, 3 hits
PROSITEiView protein in PROSITE
PS50002 SH3, 3 hits
PS50831 SOHO, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z5J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSECDVGSS KAVVNGLASG NHGPDKDMDP TKICTGKGTV TLRASSSYRG
60 70 80 90 100
TPSSSPVSPQ ESPKHESKSD EWKLSSSADT NGNAQPSPLA AKGYRSVHPS
110 120 130 140 150
LSADKPQGAT SSSSAPSEVI VVPLYLVNTD RGQGQEGTAR TPASLGPLGC
160 170 180 190 200
VHTVPATTPA ASPLTFPTLD DFIPPHLQRR PHHSQPASAC GSLSPASQTS
210 220 230 240 250
PPSPPPPLVP PVPEDLHRGL EPDLPGAVSS TGSPLLNEVS SSHIETDSQD
260 270 280 290 300
FPPTSRPSSA YPSTTIVNPT IVLLQHNREQ QKRLSSLSDP ASERRAGEQD
310 320 330 340 350
PVPTPAELTS PGRASERRAK DASRRVVRST QDLSDVSTDE VGIPLRNTER
360 370 380 390 400
SKDWYKTMFK QIHKLNRDTP EENPYFPTYK FPELPEILQN SEEDSSYTPT
410 420 430 440 450
YQFPASTPSP KSEDDDSDVH SPRYSFSDDT KSPLSVPRSK SEMNYIEGEK
460 470 480 490 500
VVKRSATLPL PARSSSLKSS PERNDWEPPD KKVDTRKYRA EPKSIYEYQP
510 520 530 540 550
GKSSVLTNEK MSRDISPEEI DLKNEPWYKF FSELEFGRPP PKKIWDYTPG
560 570 580 590 600
DCSILPREDR KTNLEKDLSF CQAELEADLE KVETVNKSPS ANSPQSSAVS
610 620 630 640 650
PTPDITSEPP GYIYSSNFHA VKRESDGTPG GLASLENERQ IYKSVLEGGD
660 670 680 690 700
IPLQGLSGLK RPSSSASTKD SESPRHFIPA DYLESTEEFI RRRHDDKEMR
710 720 730 740 750
PARAKFDFKA QTLKELPLQK GDVVYIYRQI DQNWYEGEHH GRVGIFPRTY
760 770 780 790 800
IELLPPAEKA QPRKLAPVQV LEYGEAIAKF NFNGDTQVEM SFRKGERITL
810 820 830 840 850
LRQVDENWYE GRIPGTSRQG IFPITYVDVL KRPLVKTPVD YIDLPYSSSP
860 870 880 890 900
SRSATVSPQQ PQAQQRRVTP DRSQPSLDLC SYQALYSYVP QNDDELELRD
910 920 930
GDIVDVMEKC DDGWFVGTSR RTRQFGTFPG NYVKPLYL
Length:938
Mass (Da):103,977
Last modified:April 20, 2010 - v1
Checksum:i1D0AEEB5B7EB2F20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142101 Genomic DNA No translation available.
AC144949 Genomic DNA No translation available.
AC170187 Genomic DNA No translation available.
RefSeqiNP_848139.1, NM_178362.1
UniGeneiMm.210815
Mm.440351
Mm.489013

Genome annotation databases

EnsembliENSMUST00000099467; ENSMUSP00000097066; ENSMUSG00000025006
ENSMUST00000225153; ENSMUSP00000153313; ENSMUSG00000025006
GeneIDi20411
UCSCiuc008hkp.1 mouse

Similar proteinsi

Entry informationi

Entry nameiD3Z5J3_MOUSE
AccessioniPrimary (citable) accession number: D3Z5J3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health