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Protein
Submitted name:

Sorbin and SH3 domain-containing protein 1

Gene

Sorbs1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-445355. Smooth Muscle Contraction.

Names & Taxonomyi

Protein namesi
Submitted name:
Sorbin and SH3 domain-containing protein 1Imported
Gene namesi
Name:Sorbs1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:700014. Sorbs1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiD3Z5J3.
PaxDbiD3Z5J3.
PeptideAtlasiD3Z5J3.
PRIDEiD3Z5J3.

PTM databases

iPTMnetiD3Z5J3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000025006.
ExpressionAtlasiD3Z5J3. baseline and differential.
GenevisibleiD3Z5J3. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097066.

Structurei

3D structure databases

ProteinModelPortaliD3Z5J3.
SMRiD3Z5J3. Positions 698-938.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini326 – 429104SoHoInterPro annotationAdd
BLAST
Domaini697 – 75660SH3InterPro annotationAdd
BLAST
Domaini771 – 83262SH3InterPro annotationAdd
BLAST
Domaini884 – 93855SH3InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 3 SH3 domains.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

eggNOGiKOG4225. Eukaryota.
ENOG41110AD. LUCA.
GeneTreeiENSGT00760000119190.
HOGENOMiHOG000294090.
OMAiDYIDLPF.
OrthoDBiEOG091G0172.
TreeFamiTF320680.

Family and domain databases

InterProiIPR028506. CAP/ponsin.
IPR011511. SH3_2.
IPR001452. SH3_domain.
IPR003127. SoHo_dom.
[Graphical view]
PANTHERiPTHR10663:SF202. PTHR10663:SF202. 1 hit.
PfamiPF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
PF14604. SH3_9. 1 hit.
PF02208. Sorb. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 3 hits.
SM00459. Sorb. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS50002. SH3. 3 hits.
PS50831. SOHO. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z5J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSECDVGSS KAVVNGLASG NHGPDKDMDP TKICTGKGTV TLRASSSYRG
60 70 80 90 100
TPSSSPVSPQ ESPKHESKSD EWKLSSSADT NGNAQPSPLA AKGYRSVHPS
110 120 130 140 150
LSADKPQGAT SSSSAPSEVI VVPLYLVNTD RGQGQEGTAR TPASLGPLGC
160 170 180 190 200
VHTVPATTPA ASPLTFPTLD DFIPPHLQRR PHHSQPASAC GSLSPASQTS
210 220 230 240 250
PPSPPPPLVP PVPEDLHRGL EPDLPGAVSS TGSPLLNEVS SSHIETDSQD
260 270 280 290 300
FPPTSRPSSA YPSTTIVNPT IVLLQHNREQ QKRLSSLSDP ASERRAGEQD
310 320 330 340 350
PVPTPAELTS PGRASERRAK DASRRVVRST QDLSDVSTDE VGIPLRNTER
360 370 380 390 400
SKDWYKTMFK QIHKLNRDTP EENPYFPTYK FPELPEILQN SEEDSSYTPT
410 420 430 440 450
YQFPASTPSP KSEDDDSDVH SPRYSFSDDT KSPLSVPRSK SEMNYIEGEK
460 470 480 490 500
VVKRSATLPL PARSSSLKSS PERNDWEPPD KKVDTRKYRA EPKSIYEYQP
510 520 530 540 550
GKSSVLTNEK MSRDISPEEI DLKNEPWYKF FSELEFGRPP PKKIWDYTPG
560 570 580 590 600
DCSILPREDR KTNLEKDLSF CQAELEADLE KVETVNKSPS ANSPQSSAVS
610 620 630 640 650
PTPDITSEPP GYIYSSNFHA VKRESDGTPG GLASLENERQ IYKSVLEGGD
660 670 680 690 700
IPLQGLSGLK RPSSSASTKD SESPRHFIPA DYLESTEEFI RRRHDDKEMR
710 720 730 740 750
PARAKFDFKA QTLKELPLQK GDVVYIYRQI DQNWYEGEHH GRVGIFPRTY
760 770 780 790 800
IELLPPAEKA QPRKLAPVQV LEYGEAIAKF NFNGDTQVEM SFRKGERITL
810 820 830 840 850
LRQVDENWYE GRIPGTSRQG IFPITYVDVL KRPLVKTPVD YIDLPYSSSP
860 870 880 890 900
SRSATVSPQQ PQAQQRRVTP DRSQPSLDLC SYQALYSYVP QNDDELELRD
910 920 930
GDIVDVMEKC DDGWFVGTSR RTRQFGTFPG NYVKPLYL
Length:938
Mass (Da):103,977
Last modified:April 20, 2010 - v1
Checksum:i1D0AEEB5B7EB2F20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC144949 Genomic DNA. No translation available.
AC170187 Genomic DNA. No translation available.
RefSeqiNP_848139.1. NM_178362.1.
UniGeneiMm.210815.
Mm.440351.
Mm.489013.

Genome annotation databases

EnsembliENSMUST00000099467; ENSMUSP00000097066; ENSMUSG00000025006.
GeneIDi20411.
UCSCiuc008hkp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC144949 Genomic DNA. No translation available.
AC170187 Genomic DNA. No translation available.
RefSeqiNP_848139.1. NM_178362.1.
UniGeneiMm.210815.
Mm.440351.
Mm.489013.

3D structure databases

ProteinModelPortaliD3Z5J3.
SMRiD3Z5J3. Positions 698-938.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097066.

PTM databases

iPTMnetiD3Z5J3.

Proteomic databases

MaxQBiD3Z5J3.
PaxDbiD3Z5J3.
PeptideAtlasiD3Z5J3.
PRIDEiD3Z5J3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000099467; ENSMUSP00000097066; ENSMUSG00000025006.
GeneIDi20411.
UCSCiuc008hkp.1. mouse.

Organism-specific databases

CTDi10580.
MGIiMGI:700014. Sorbs1.

Phylogenomic databases

eggNOGiKOG4225. Eukaryota.
ENOG41110AD. LUCA.
GeneTreeiENSGT00760000119190.
HOGENOMiHOG000294090.
OMAiDYIDLPF.
OrthoDBiEOG091G0172.
TreeFamiTF320680.

Enzyme and pathway databases

ReactomeiR-MMU-445355. Smooth Muscle Contraction.

Miscellaneous databases

ChiTaRSiSorbs1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000025006.
ExpressionAtlasiD3Z5J3. baseline and differential.
GenevisibleiD3Z5J3. MM.

Family and domain databases

InterProiIPR028506. CAP/ponsin.
IPR011511. SH3_2.
IPR001452. SH3_domain.
IPR003127. SoHo_dom.
[Graphical view]
PANTHERiPTHR10663:SF202. PTHR10663:SF202. 1 hit.
PfamiPF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
PF14604. SH3_9. 1 hit.
PF02208. Sorb. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 3 hits.
SM00459. Sorb. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS50002. SH3. 3 hits.
PS50831. SOHO. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z5J3_MOUSE
AccessioniPrimary (citable) accession number: D3Z5J3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.