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D3Z5H2

- D3Z5H2_MOUSE

UniProt

D3Z5H2 - D3Z5H2_MOUSE

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Protein
Submitted name:

DNA repair protein XRCC2

Gene

Xrcc2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA-dependent ATPase activity Source: InterPro
  3. four-way junction DNA binding Source: Ensembl

GO - Biological processi

  1. cellular response to DNA damage stimulus Source: MGI
  2. centrosome organization Source: Ensembl
  3. double-strand break repair via homologous recombination Source: MGI
  4. in utero embryonic development Source: MGI
  5. mitotic cell cycle Source: Ensembl
  6. multicellular organism growth Source: MGI
  7. negative regulation of neuron apoptotic process Source: MGI
  8. neurogenesis Source: MGI
  9. positive regulation of neurogenesis Source: MGI
  10. regulation of fibroblast apoptotic process Source: MGI
  11. response to gamma radiation Source: MGI
  12. response to X-ray Source: MGI
  13. somitogenesis Source: MGI
  14. strand invasion Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DNA repair protein XRCC2Imported
Submitted name:
X-ray repair complementing defective repair in Chinese hamster cells 2, isoform CRA_aImported
Gene namesi
Name:Xrcc2Imported
ORF Names:mCG_1077Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:1927345. Xrcc2.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: Ensembl
  2. Rad51B-Rad51C-Rad51D-XRCC2 complex Source: Ensembl
  3. replication fork Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000020445.
HOGENOMiHOG000004802.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR013632. DNA_recomb/repair_Rad51_C.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z5H2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLYHLTARCI LPKSEGGLQI EVLFIDTDYH FDMLRLVTVL EHRLSQSSEE
60 70 80 90 100
AMKLCLARLF LAYCSSSMQL LLTLHSLEAL LCSRPSLCLL IVDSLSSFYW
110 120 130 140 150
IDRVSGGESV ALQESTLQKC SQLLERLVTE YRLLLFATTQ SLMQKGSDSA
160 170 180 190 200
DGPSSSKHPC DGDMGYRAYL CKAWQRVVKH RVIFSRDDEA KSSRFSLVSR
210 220
HLKSNSLKKH SFMVRESGVE FC
Length:222
Mass (Da):25,199
Last modified:April 20, 2010 - v1
Checksum:iF2564A34CBD9EC85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159977 Genomic DNA. No translation available.
CH466586 Genomic DNA. Translation: EDL03073.1.
UniGeneiMm.143767.

Genome annotation databases

EnsembliENSMUST00000114922; ENSMUSP00000110572; ENSMUSG00000028933.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159977 Genomic DNA. No translation available.
CH466586 Genomic DNA. Translation: EDL03073.1 .
UniGenei Mm.143767.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000114922 ; ENSMUSP00000110572 ; ENSMUSG00000028933 .

Organism-specific databases

MGIi MGI:1927345. Xrcc2.

Phylogenomic databases

GeneTreei ENSGT00390000020445.
HOGENOMi HOG000004802.

Miscellaneous databases

NextBioi 35551243.
SOURCEi Search...

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR013632. DNA_recomb/repair_Rad51_C.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
[Graphical view ]
Pfami PF08423. Rad51. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS50162. RECA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z5H2_MOUSE
AccessioniPrimary (citable) accession number: D3Z5H2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

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