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D3Z5H2

- D3Z5H2_MOUSE

UniProt

D3Z5H2 - D3Z5H2_MOUSE

Protein
Submitted name:

DNA repair protein XRCC2

Gene

Xrcc2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. DNA binding Source: InterPro
    3. DNA-dependent ATPase activity Source: InterPro

    GO - Biological processi

    1. cellular response to DNA damage stimulus Source: MGI
    2. double-strand break repair via homologous recombination Source: MGI
    3. in utero embryonic development Source: MGI
    4. negative regulation of neuron apoptotic process Source: MGI
    5. positive regulation of neurogenesis Source: MGI
    6. response to gamma radiation Source: MGI
    7. response to X-ray Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    DNA repair protein XRCC2Imported
    Submitted name:
    X-ray repair complementing defective repair in Chinese hamster cells 2, isoform CRA_aImported
    Gene namesi
    Name:Xrcc2Imported
    ORF Names:mCG_1077Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:1927345. Xrcc2.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000020445.
    HOGENOMiHOG000004802.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR013632. DNA_recomb/repair_Rad51_C.
    IPR027417. P-loop_NTPase.
    IPR020588. RecA_ATP-bd.
    [Graphical view]
    PfamiPF08423. Rad51. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS50162. RECA_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D3Z5H2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLYHLTARCI LPKSEGGLQI EVLFIDTDYH FDMLRLVTVL EHRLSQSSEE    50
    AMKLCLARLF LAYCSSSMQL LLTLHSLEAL LCSRPSLCLL IVDSLSSFYW 100
    IDRVSGGESV ALQESTLQKC SQLLERLVTE YRLLLFATTQ SLMQKGSDSA 150
    DGPSSSKHPC DGDMGYRAYL CKAWQRVVKH RVIFSRDDEA KSSRFSLVSR 200
    HLKSNSLKKH SFMVRESGVE FC 222
    Length:222
    Mass (Da):25,199
    Last modified:April 20, 2010 - v1
    Checksum:iF2564A34CBD9EC85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159977 Genomic DNA. No translation available.
    CH466586 Genomic DNA. Translation: EDL03073.1.
    UniGeneiMm.143767.

    Genome annotation databases

    EnsembliENSMUST00000114922; ENSMUSP00000110572; ENSMUSG00000028933.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159977 Genomic DNA. No translation available.
    CH466586 Genomic DNA. Translation: EDL03073.1 .
    UniGenei Mm.143767.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000114922 ; ENSMUSP00000110572 ; ENSMUSG00000028933 .

    Organism-specific databases

    MGIi MGI:1927345. Xrcc2.

    Phylogenomic databases

    GeneTreei ENSGT00390000020445.
    HOGENOMi HOG000004802.

    Miscellaneous databases

    NextBioi 35551243.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR013632. DNA_recomb/repair_Rad51_C.
    IPR027417. P-loop_NTPase.
    IPR020588. RecA_ATP-bd.
    [Graphical view ]
    Pfami PF08423. Rad51. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS50162. RECA_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD3Z5H2_MOUSE
    AccessioniPrimary (citable) accession number: D3Z5H2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3