D3Z5H2 (D3Z5H2_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA repair protein XRCC2 Ensembl ENSMUSP00000110572

Submitted name:
X-ray repair complementing defective repair in Chinese hamster cells 2, isoform CRA_a EMBL EDL03073.1

Gene names

Name:	Xrcc2 Ensembl ENSMUSP00000110572 MGI 1927345 EMBL EDL03073.1
ORF Names:	mCG_1077 EMBL EDL03073.1

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000110572

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	double-strand break repair via homologous recombination Inferred from mutant phenotype PubMed 16777961. Source: MGI in utero embryonic development Inferred from mutant phenotype PubMed 16777961. Source: MGI negative regulation of neuron apoptotic process Inferred from genetic interaction PubMed 16777961. Source: MGI positive regulation of neurogenesis Inferred from mutant phenotype PubMed 16777961. Source: MGI response to X-ray Inferred from mutant phenotype PubMed 15979950. Source: MGI response to gamma radiation Inferred from mutant phenotype PubMed 16777961. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D3Z5H2 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: F2564A34CBD9EC85	FASTA	222	25,199
	10 20 30 40 50 60 MLYHLTARCI LPKSEGGLQI EVLFIDTDYH FDMLRLVTVL EHRLSQSSEE AMKLCLARLF 70 80 90 100 110 120 LAYCSSSMQL LLTLHSLEAL LCSRPSLCLL IVDSLSSFYW IDRVSGGESV ALQESTLQKC 130 140 150 160 170 180 SQLLERLVTE YRLLLFATTQ SLMQKGSDSA DGPSSSKHPC DGDMGYRAYL CKAWQRVVKH 190 200 210 220 RVIFSRDDEA KSSRFSLVSR HLKSNSLKKH SFMVRESGVE FC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL03073.1.
[2]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL03073.1.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000110572.
[4]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000110572.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC159977 Genomic DNA. No translation available. CH466586 Genomic DNA. Translation: EDL03073.1.
IPI	IPI00858210.
UniGene	Mm.143767.
3D structure databases
SMR	D3Z5H2. Positions 11-140.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000114922; ENSMUSP00000110572; ENSMUSG00000028933.
Organism-specific databases
MGI	MGI:1927345. Xrcc2.
Phylogenomic databases
GeneTree	ENSGT00390000020445.
HOGENOM	HOG000004802.
Family and domain databases
InterPro	IPR013632. DNA_recomb/repair_Rad51_C. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF08423. Rad51. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
ProtoNet	Search...
Other
NextBio	35551243.
SOURCE	Search...

Entry information

Entry name

D3Z5H2_MOUSE

Accession

Primary (citable) accession number: D3Z5H2

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	May 29, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)