ID   D3Z4M5_MOUSE            Unreviewed;       516 AA.
AC   D3Z4M5;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Fas-activated serine/threonine kinase {ECO:0000313|Ensembl:ENSMUSP00000110695.2};
GN   Name=Fastk {ECO:0000313|Ensembl:ENSMUSP00000110695.2,
GN   ECO:0000313|MGI:MGI:1913837};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000110695.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000110695.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000110695.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000110695.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000110695.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; D3Z4M5; -.
DR   SMR; D3Z4M5; -.
DR   MaxQB; D3Z4M5; -.
DR   ProteomicsDB; 308399; -.
DR   Antibodypedia; 32964; 310 antibodies from 25 providers.
DR   Ensembl; ENSMUST00000115043.8; ENSMUSP00000110695.2; ENSMUSG00000028959.15.
DR   UCSC; uc008wrn.1; mouse.
DR   AGR; MGI:1913837; -.
DR   MGI; MGI:1913837; Fastk.
DR   VEuPathDB; HostDB:ENSMUSG00000028959; -.
DR   GeneTree; ENSGT01030000234607; -.
DR   ChiTaRS; Fastk; mouse.
DR   Proteomes; UP000000589; Chromosome 5.
DR   Bgee; ENSMUSG00000028959; Expressed in hindlimb stylopod muscle and 254 other cell types or tissues.
DR   ExpressionAtlas; D3Z4M5; baseline and differential.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IEA:InterPro.
DR   InterPro; IPR013579; FAST_2.
DR   InterPro; IPR010622; FAST_Leu-rich.
DR   InterPro; IPR013584; RAP.
DR   PANTHER; PTHR21228:SF4; FAS-ACTIVATED SERINE_THREONINE KINASE; 1.
DR   PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR   Pfam; PF06743; FAST_1; 1.
DR   Pfam; PF08368; FAST_2; 1.
DR   Pfam; PF08373; RAP; 1.
DR   PROSITE; PS51286; RAP; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Proteomics identification {ECO:0007829|EPD:D3Z4M5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          473..516
FT                   /note="RAP"
FT                   /evidence="ECO:0000259|PROSITE:PS51286"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   516 AA;  57986 MW;  212D57C71D88BCE4 CRC64;
     MRRPRGEPGS RAPRPAERVT YAGPGESWSP PPSSMLRILL SAQTSPARLS GLLLIPPVQP
     CCLGPSKSGD RPFGGGPVQG LQRLLEQARS PGELLRWLSQ NPTKVRAHHY PVALRRLGQL
     LVSQPRPSPV EQATLQDLSQ LIIRNCPSFD VHTIHVCLHL AVLLGFPSDG PLLCALEQER
     RSRLPPKPPS PHRPAIYGGQ RLEVALSCPR FLQYPRQHLI RSLAEARPEE LTPHVMVLLA
     QHLARHRLRE PQLLEAIAHF LVVQEAQLNS KVVQKLVLPF GRLNYMPLEQ QFMPCLERIL
     AREAGVAPLA TVNILMSLCQ LQCLPFRALQ FVFSPSFINH INGTPPSLIV RRYLSLLDTA
     VELELPGYQG PRLPQRQRVP IFPQPLITDR ARCKYSHKDM VAEGLRQLLG EENYRQNLTV
     PPGYCTDFLL CVSSSGAVLP MRTQDPFLPY PPRSCQQDQA NFNSTTQDPA QRVVLMLRER
     WHFCRDGRVL LGSRALRERH LGLMGYQLLP VPQPCS
//