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Protein

RNA-binding protein 24

Gene

Rbm24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays a role in myogenic differentiation by regulating MYOG levels. Binds to the 3'-UTR of MYOG mRNA and regulates its stability (By similarity).By similarity

GO - Molecular functioni

  • mRNA 3'-UTR binding Source: UniProtKB

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • regulation of mRNA stability Source: UniProtKB
  • regulation of myotube differentiation Source: UniProtKB

Keywordsi

Molecular functionRNA-binding
Biological processDifferentiation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein 24
Alternative name(s):
RNA-binding motif protein 24
Gene namesi
Name:Rbm24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:3610364 Rbm24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004161171 – 236RNA-binding protein 24Add BLAST236

Proteomic databases

MaxQBiD3Z4I3
PaxDbiD3Z4I3
PeptideAtlasiD3Z4I3
PRIDEiD3Z4I3

PTM databases

PhosphoSitePlusiD3Z4I3

Expressioni

Gene expression databases

BgeeiENSMUSG00000038132
GenevisibleiD3Z4I3 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043120

Structurei

3D structure databases

ProteinModelPortaliD3Z4I3
SMRiD3Z4I3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 88RRMPROSITE-ProRule annotationAdd BLAST78

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi141 – 221Ala-richAdd BLAST81

Phylogenomic databases

eggNOGiKOG0149 Eukaryota
ENOG4111PGT LUCA
GeneTreeiENSGT00390000002308
HOGENOMiHOG000276232
InParanoidiD3Z4I3
OMAiATSPYID
OrthoDBiEOG091G13K0
PhylomeDBiD3Z4I3
TreeFamiTF314235

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z4I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTTQKDTTY TKIFVGGLPY HTTDASLRKY FEVFGDIEEA VVITDRQTGK
60 70 80 90 100
SRGYGFVTMA DRAAAERACK DPNPIIDGRK ANVNLAYLGA KPRIMQPGFA
110 120 130 140 150
FGVQQLHPAL IQRPFGIPAH YVYPQAFVQP GVVIPHVQPT AAAASTTPYI
160 170 180 190 200
DYTGAAYAQY SAAAAAAAAA AAYDQYPYAA SPAAAGYVTT GGYSYAVQQP
210 220 230
ITAAAPGTAA AAAAAAAAAA AFGQYQPQQL QTDRMQ
Length:236
Mass (Da):24,822
Last modified:April 20, 2010 - v1
Checksum:i770ECF253A088E25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124411 Genomic DNA No translation available.
CCDSiCCDS36651.1
RefSeqiNP_001074894.1, NM_001081425.1
UniGeneiMm.38269

Genome annotation databases

EnsembliENSMUST00000037923; ENSMUSP00000043120; ENSMUSG00000038132
GeneIDi666794
KEGGimmu:666794
UCSCiuc007qhe.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRBM24_MOUSE
AccessioniPrimary (citable) accession number: D3Z4I3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: April 20, 2010
Last modified: March 28, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health