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Protein

RNA-binding protein 24

Gene

Rbm24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Plays a role in myogenic differentiation by regulating MYOG levels. Binds to the 3'-UTR of MYOG mRNA and regulates its stability (By similarity).By similarity

GO - Molecular functioni

  • mRNA 3'-UTR binding Source: UniProtKB
  • nucleotide binding Source: InterPro

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • regulation of mRNA stability Source: UniProtKB
  • regulation of myotube differentiation Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Differentiation

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein 24
Alternative name(s):
RNA-binding motif protein 24
Gene namesi
Name:Rbm24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:3610364. Rbm24.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 236236RNA-binding protein 24PRO_0000416117Add
BLAST

Proteomic databases

EPDiD3Z4I3.
PaxDbiD3Z4I3.

Expressioni

Gene expression databases

BgeeiD3Z4I3.
GenevisibleiD3Z4I3. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043120.

Structurei

3D structure databases

ProteinModelPortaliD3Z4I3.
SMRiD3Z4I3. Positions 5-103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 8878RRMPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi141 – 22181Ala-richAdd
BLAST

Sequence similaritiesi

Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0149. Eukaryota.
ENOG4111PGT. LUCA.
GeneTreeiENSGT00390000002308.
HOGENOMiHOG000276232.
InParanoidiD3Z4I3.
OMAiSSPYIDY.
OrthoDBiEOG77M8Q4.
PhylomeDBiD3Z4I3.
TreeFamiTF314235.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z4I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTTQKDTTY TKIFVGGLPY HTTDASLRKY FEVFGDIEEA VVITDRQTGK
60 70 80 90 100
SRGYGFVTMA DRAAAERACK DPNPIIDGRK ANVNLAYLGA KPRIMQPGFA
110 120 130 140 150
FGVQQLHPAL IQRPFGIPAH YVYPQAFVQP GVVIPHVQPT AAAASTTPYI
160 170 180 190 200
DYTGAAYAQY SAAAAAAAAA AAYDQYPYAA SPAAAGYVTT GGYSYAVQQP
210 220 230
ITAAAPGTAA AAAAAAAAAA AFGQYQPQQL QTDRMQ
Length:236
Mass (Da):24,822
Last modified:April 20, 2010 - v1
Checksum:i770ECF253A088E25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124411 Genomic DNA. No translation available.
CCDSiCCDS36651.1.
RefSeqiNP_001074894.1. NM_001081425.1.
UniGeneiMm.38269.

Genome annotation databases

EnsembliENSMUST00000037923; ENSMUSP00000043120; ENSMUSG00000038132.
GeneIDi666794.
KEGGimmu:666794.
UCSCiuc007qhe.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124411 Genomic DNA. No translation available.
CCDSiCCDS36651.1.
RefSeqiNP_001074894.1. NM_001081425.1.
UniGeneiMm.38269.

3D structure databases

ProteinModelPortaliD3Z4I3.
SMRiD3Z4I3. Positions 5-103.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043120.

Proteomic databases

EPDiD3Z4I3.
PaxDbiD3Z4I3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000037923; ENSMUSP00000043120; ENSMUSG00000038132.
GeneIDi666794.
KEGGimmu:666794.
UCSCiuc007qhe.1. mouse.

Organism-specific databases

CTDi221662.
MGIiMGI:3610364. Rbm24.

Phylogenomic databases

eggNOGiKOG0149. Eukaryota.
ENOG4111PGT. LUCA.
GeneTreeiENSGT00390000002308.
HOGENOMiHOG000276232.
InParanoidiD3Z4I3.
OMAiSSPYIDY.
OrthoDBiEOG77M8Q4.
PhylomeDBiD3Z4I3.
TreeFamiTF314235.

Miscellaneous databases

NextBioi430851.
PROiD3Z4I3.
SOURCEiSearch...

Gene expression databases

BgeeiD3Z4I3.
GenevisibleiD3Z4I3. MM.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.

Entry informationi

Entry nameiRBM24_MOUSE
AccessioniPrimary (citable) accession number: D3Z4I3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: April 20, 2010
Last modified: May 11, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.