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Protein
Submitted name:

Adhesion G protein-coupled receptor L3

Gene

Adgrl3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor L3Imported
Gene namesi
Name:Adgrl3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:2441950. Adgrl3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei947 – 97024HelicalSequence analysisAdd
BLAST
Transmembranei982 – 100019HelicalSequence analysisAdd
BLAST
Transmembranei1006 – 102823HelicalSequence analysisAdd
BLAST
Transmembranei1049 – 106921HelicalSequence analysisAdd
BLAST
Transmembranei1089 – 111224HelicalSequence analysisAdd
BLAST
Transmembranei1143 – 116523HelicalSequence analysisAdd
BLAST
Transmembranei1171 – 119424HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 13081289Sequence analysisPRO_5003052594Add
BLAST

Proteomic databases

PaxDbiD3Z3X6.

Expressioni

Gene expression databases

BgeeiD3Z3X6.
ExpressionAtlasiD3Z3X6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000072336.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini103 – 19290SUEL-type lectinInterPro annotationAdd
BLAST
Domaini202 – 461260Olfactomedin-likeInterPro annotationAdd
BLAST
Domaini566 – 62257G_PROTEIN_RECEP_F2_3InterPro annotationAdd
BLAST
Domaini883 – 93452GPSInterPro annotationAdd
BLAST
Domaini945 – 1195251G_PROTEIN_RECEP_F2_4InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation
Contains 1 SUEL-type lectin domain.UniRule annotation
Contains GPS domain.SAAS annotation
Contains olfactomedin-like domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3545. Eukaryota.
KOG4193. Eukaryota.
KOG4729. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00830000128227.
HOGENOMiHOG000049065.

Family and domain databases

InterProiIPR032471. GAIN_dom_N.
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003924. GPCR_2_latrophilin.
IPR003334. GPCR_2_latrophilin_rcpt_C.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR015630. Latrophilin-3.
IPR000922. Lectin_gal-bd_dom.
IPR003112. Olfac-like_dom.
[Graphical view]
PANTHERiPTHR12011:SF60. PTHR12011:SF60. 2 hits.
PfamiPF00002. 7tm_2. 1 hit.
PF16489. GAIN. 1 hit.
PF02140. Gal_Lectin. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF02354. Latrophilin. 1 hit.
PF02191. OLF. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
PR01444. LATROPHILIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00284. OLF. 1 hit.
[Graphical view]
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS51132. OLF. 1 hit.
PS50228. SUEL_LECTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z3X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWPPQLLILT MLLAPVVHGG KHNERHPALA APLRHAERSP GGALPPRHLL
60 70 80 90 100
QQPAAERSTA HRGQGPRGAA RGVRGPGAPG AQIAAQAFSR APIPMAVVRR
110 120 130 140 150
ELSCESYPIE LRCPGTDVIM IESANYGRTD DKICDSDPAQ MENIRCYLPD
160 170 180 190 200
AYKIMSQRCN NRTQCAVVAG PDVFPDPCPG TYKYLEVQYE CVPYKVEQKV
210 220 230 240 250
FLCPGLLKGV YQSEHLFESD HQSGAWCKDP LQASDKIYYM PWTPYRTDTL
260 270 280 290 300
TEYSSKDDFI AGRPTTTYKL PHRVDGTGFV VYDGALFFNK ERTRNIVKFD
310 320 330 340 350
LRTRIKSGEA IIANANYHDT SPYRWGGKSD IDLAVDENGL WVIYATEQNN
360 370 380 390 400
GKIVISQLNP YTLRIEGTWD TAYDKRSASN AFMICGILYV VKSVYEDDDN
410 420 430 440 450
EATGNKIDYI YNTDQSKDSL VDVPFPNSYQ YIAAVDYNPR DNLLYVWNNY
460 470 480 490 500
HVVKYSLDFG PLDSRSGPVH HGQVSYISPP IHLDSELERP PVRGISTTGS
510 520 530 540 550
LGMGSTTTST TLRTTTWNIG RSTTASLPGR RNRSTSTPSP AVEVLDDVTT
560 570 580 590 600
HLPSAASQIP AMEESCEAVE AREIMWFKTR QGQVAKQPCP AGTIGVSTYL
610 620 630 640 650
CLAPDGIWDP QGPDLSNCSS PWVNHITQKL KSGETAANIA RELAEQTRNH
660 670 680 690 700
LNAGDITYSV RAMDQLVGLL DVQLRNLTPG GKDSAARSLN KLQKRERSCR
710 720 730 740 750
AYVQAMVETV NNLLQPQALN AWRDLTTSDQ LRAATMLLDT VEESAFVLAD
760 770 780 790 800
NLLKTDIVRE NTDNIQLEVA RLSTEGNLED LKFPENMGHG STIQLSANTL
810 820 830 840 850
KQNGRNGEIR VAFVLYNNLG PYLSTENASM KLGTEAMSTN HSVIVNSPVI
860 870 880 890 900
TAAINKEFSN KVYLADPVVF TVKHIKQSEE NFNPNCSFWS YSKRTMTGYW
910 920 930 940 950
STQGCRLLTT NKTHTTCSCN HLTNFAVLMA HVEVKHSDAV HDLLLDVITW
960 970 980 990 1000
VGILLSLVCL LICIFTFCFF RGLQSDRNTI HKNLCISLFV AELLFLIGIN
1010 1020 1030 1040 1050
RTDQPIACAV FAALLHFFFL AAFTWMFLEG VQLYIMLVEV FESEHSRRKY
1060 1070 1080 1090 1100
FYLVGYGMPA LIVAVSAAVD YRSYGTDKVC WLRLDTYFIW SFIGPATLII
1110 1120 1130 1140 1150
MLNVIFLGIA LYKMFHHTAI LKPESGCLDN INYEDNRPFI KSWVIGAIAL
1160 1170 1180 1190 1200
LCLLGLTWAF GLMYINESTV IMAYLFTIFN SLQGMFIFIF HCVLQKKVRK
1210 1220 1230 1240 1250
EYGKCLRTHC CSGKSTESSI GSGKTSGSRT PGRYSTGSQS RIRRMWNDTV
1260 1270 1280 1290 1300
RKQSESSFIT GDINSSASLN REPYRETSMG VKLNIAYQIG ASEQCQGYKC

HGYSTTEW
Length:1,308
Mass (Da):146,143
Last modified:April 20, 2010 - v1
Checksum:iAAF27E47E03C90A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102517 Genomic DNA. No translation available.
AC104196 Genomic DNA. No translation available.
AC114425 Genomic DNA. No translation available.
AC114622 Genomic DNA. No translation available.
AC121837 Genomic DNA. No translation available.
AC122054 Genomic DNA. No translation available.
AC124825 Genomic DNA. No translation available.
AC155075 Genomic DNA. No translation available.
RefSeqiXP_011247775.1. XM_011249473.1.
UniGeneiMm.273631.
Mm.461016.

Genome annotation databases

EnsembliENSMUST00000118442; ENSMUSP00000113836; ENSMUSG00000037605.
GeneIDi319387.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102517 Genomic DNA. No translation available.
AC104196 Genomic DNA. No translation available.
AC114425 Genomic DNA. No translation available.
AC114622 Genomic DNA. No translation available.
AC121837 Genomic DNA. No translation available.
AC122054 Genomic DNA. No translation available.
AC124825 Genomic DNA. No translation available.
AC155075 Genomic DNA. No translation available.
RefSeqiXP_011247775.1. XM_011249473.1.
UniGeneiMm.273631.
Mm.461016.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000072336.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiD3Z3X6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000118442; ENSMUSP00000113836; ENSMUSG00000037605.
GeneIDi319387.

Organism-specific databases

CTDi23284.
MGIiMGI:2441950. Adgrl3.

Phylogenomic databases

eggNOGiKOG3545. Eukaryota.
KOG4193. Eukaryota.
KOG4729. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00830000128227.
HOGENOMiHOG000049065.

Miscellaneous databases

ChiTaRSiLphn3. mouse.
NextBioi35550875.
SOURCEiSearch...

Gene expression databases

BgeeiD3Z3X6.
ExpressionAtlasiD3Z3X6. baseline and differential.

Family and domain databases

InterProiIPR032471. GAIN_dom_N.
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003924. GPCR_2_latrophilin.
IPR003334. GPCR_2_latrophilin_rcpt_C.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR015630. Latrophilin-3.
IPR000922. Lectin_gal-bd_dom.
IPR003112. Olfac-like_dom.
[Graphical view]
PANTHERiPTHR12011:SF60. PTHR12011:SF60. 2 hits.
PfamiPF00002. 7tm_2. 1 hit.
PF16489. GAIN. 1 hit.
PF02140. Gal_Lectin. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF02354. Latrophilin. 1 hit.
PF02191. OLF. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
PR01444. LATROPHILIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00284. OLF. 1 hit.
[Graphical view]
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS51132. OLF. 1 hit.
PS50228. SUEL_LECTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z3X6_MOUSE
AccessioniPrimary (citable) accession number: D3Z3X6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 11, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.