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Protein
Submitted name:

Solute carrier family 12 member 8

Gene

Slc12a8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 12 member 8Imported
Gene namesi
Name:Slc12a8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2443672. Slc12a8.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 3920HelicalSequence analysisAdd
BLAST
Transmembranei60 – 8223HelicalSequence analysisAdd
BLAST
Transmembranei114 – 14027HelicalSequence analysisAdd
BLAST
Transmembranei332 – 35322HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiD3Z3V1.

Expressioni

Gene expression databases

BgeeiD3Z3V1.
ExpressionAtlasiD3Z3V1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062337.

Structurei

3D structure databases

ProteinModelPortaliD3Z3V1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 161160AA_permeaseInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2083. Eukaryota.
COG0531. LUCA.
GeneTreeiENSGT00760000119053.
HOGENOMiHOG000045198.

Family and domain databases

InterProiIPR004841. AA-permease/SLC12A_dom.
[Graphical view]
PfamiPF00324. AA_permease. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D3Z3V1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGFNMGGDL RDPADSVPLG SLAAVGVSWF LYIIFAFLLG AVCTREALRS
60 70 80 90 100
DFLIAEKVSL VGFLFLLGLY ISSLASCMGG LYGAPRILQC IAQDKVIPAL
110 120 130 140 150
AFLANGKGPN KTPVAAICLT SLVTMAFVLV GQVNVLAPVV TINFMLTYIM
160 170 180 190 200
VDYSYFALSM AHCGLAPSPE PVPRQGPDTL HCSEHLLQDR APSYGSDVPA
210 220 230 240 250
RSLSEGTLLE FTKDMDQFLQ PIEELESRQL GSREGNNPKN QKRKGKKGAK
260 270 280 290 300
QTLQDSFLLD PGSPLSFPTR TSERLSVAFC GEQESYQKQQ TSRSESHDHL
310 320 330 340 350
VPDLRNQPRV NREDFFLKCR LQEQEIQRRP SVFYACMCNP WVSLLGALAS
360 370 380 390 400
LLIMFVIQWL YTLASMGVAA LVYFYIGQAS PGLYLGSASN FSFFQWMKSF
410 420 430 440 450
LVPSCRSLRS AQEQIILAPS PAKVDMAMTQ LTQDNADFAT RDRYHHSSFL

SREQLMPPY
Length:459
Mass (Da):50,785
Last modified:April 20, 2010 - v1
Checksum:iE5BD3E2D1248ACED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121570 Genomic DNA. No translation available.
AC127412 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000122314; ENSMUSP00000113901; ENSMUSG00000035506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121570 Genomic DNA. No translation available.
AC127412 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD3Z3V1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062337.

Proteomic databases

PaxDbiD3Z3V1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000122314; ENSMUSP00000113901; ENSMUSG00000035506.

Organism-specific databases

MGIiMGI:2443672. Slc12a8.

Phylogenomic databases

eggNOGiKOG2083. Eukaryota.
COG0531. LUCA.
GeneTreeiENSGT00760000119053.
HOGENOMiHOG000045198.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiD3Z3V1.
ExpressionAtlasiD3Z3V1. baseline and differential.

Family and domain databases

InterProiIPR004841. AA-permease/SLC12A_dom.
[Graphical view]
PfamiPF00324. AA_permease. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD3Z3V1_MOUSE
AccessioniPrimary (citable) accession number: D3Z3V1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: June 8, 2016
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.