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Protein
Submitted name:

Activated CDC42 kinase 1

Gene

Tnk2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, ReceptorImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Activated CDC42 kinase 1Imported
Submitted name:
Tyrosine kinase, non-receptor, 2, isoform CRA_bImported
Gene namesi
Name:Tnk2Imported
ORF Names:mCG_130126Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1858308 Tnk2

Expressioni

Gene expression databases

BgeeiENSMUSG00000022791

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 24GTPase_bindingInterPro annotationAdd BLAST24
Domaini284 – 349Inhibitor_Mig-6InterPro annotationAdd BLAST66

Phylogenomic databases

eggNOGiKOG0199 Eukaryota
ENOG410XPRC LUCA
GeneTreeiENSGT00760000118799
HOGENOMiHOG000170178

Family and domain databases

InterProiView protein in InterPro
IPR030220 Ack1
IPR015116 Cdc42_binding_dom-like
IPR021619 Mig-6
IPR009060 UBA-like_sf
PANTHERiPTHR14254:SF4 PTHR14254:SF4, 1 hit
PfamiView protein in Pfam
PF09027 GTPase_binding, 1 hit
PF11555 Inhibitor_Mig-6, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z3U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPPDLLSVE LSTSRPTQHL GRVKKPTYDP VSEDPDPLSS DFKRLGLRKP
60 70 80 90 100
ALPRGLWLAK PSARVPGTKA DRSSGGEVTL IDFGEEPVVP TPRPCAPSLA
110 120 130 140 150
QLAMDACSLL DKTPPQSPTR ALPRPLHPTP VVDWDARPLP PPPAYDDVAQ
160 170 180 190 200
DEDDFEVCSI NSTLVGAGLP AGPSQGETNY AFVPEQAQMP PALEDNLFLP
210 220 230 240 250
PQGGGKPPSS VQTAEIFQAL QQECMRQLQV PTGQLTPSPT PGGDDKPQVP
260 270 280 290 300
PRVPIPPRPT RPRVELSPAP SGEEETSRWP GPASPPRVPP REPLSPQGSR
310 320 330 340 350
TPSPLVPPGS SPLPHRLSSS PGKTMPTTQS FASDPKYATP QVIQAPGPRA
360 370 380 390 400
GPCILPIVRD GRKVSSTHYY LLPERPPYLE RYQRFLREAQ SPEEPAALPV
410 420 430 440 450
PPLLPPPSTP APAAPTATVR PMPQAAPDPK ANFSTNNSNP GARPPSLRAT
460 470 480 490 500
ARLPQRGCPG DGQEAARPAD KVQMLQAMVH GVTTEECQAA LQSHSWSVQR
510 520 530 540 550
AAQYLKVEQL FGLGLRPRVE CHKVLEMFDW NLEQAGCHLL GSCGPAHHKR
Length:550
Mass (Da):59,148
Last modified:April 20, 2010 - v1
Checksum:iAE9D84387D6CE5AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161755 Genomic DNA No translation available.
CH466521 Genomic DNA Translation: EDK97802.1
CH466521 Genomic DNA Translation: EDK97806.1
RefSeqiNP_001334114.1, NM_001347185.1
UniGeneiMm.251115

Genome annotation databases

EnsembliENSMUST00000115120; ENSMUSP00000110773; ENSMUSG00000022791
GeneIDi51789
UCSCiuc007yzf.3 mouse

Similar proteinsi

Entry informationi

Entry nameiD3Z3U7_MOUSE
AccessioniPrimary (citable) accession number: D3Z3U7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health